Publications by authors named "Gregory P Tochtrop"

Claim this Profile
R
Rationally Designed, Short-Acting RPE65 Inhibitors for Visual Cycle-Associated Retinopathies.
Marco Bassetto, Yulun Hu, Bowen Li, Xiuyuan Chen, Vivek Saraswat, Gregory P Tochtrop

J Med Chem· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Advances and therapeutic opportunities in visual cycle modulation.
Jordan Zaluski, Marco Bassetto, Philip D Kiser, Gregory P Tochtrop

Prog Retin Eye Res· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The unique reactivity of EKODE lipid peroxidation products allows in vivo detection of inflammation.
Chuan Shi, Roozbeh Eskandari, Jianye Zhang, Guofang Zhang, Li Li, Gregory P Tochtrop

Proc Natl Acad Sci U S A· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An Acid-Controlled Method for the Regioselective Functionalization of Anilines over Aliphatic Amines.
Bowen Li, Yulun Hu, Gregory P Tochtrop

Chemistry· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Tuning the Metabolic Stability of Visual Cycle Modulators through Modification of an RPE65 Recognition Motif.
Marco Bassetto, Jordan Zaluski, Bowen Li, Jianye Zhang, Mohsen Badiee, Gregory P Tochtrop

J Med Chem· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nonretinoid chaperones improve rhodopsin homeostasis in a mouse model of retinitis pigmentosa.
Abhishek Vats, Yibo Xi, Bing Feng, Owen D Clinger, Anthony J St Leger, Gregory P Tochtrop

JCI Insight· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Rapid Access to γ-Amino-α-aryl Alcohol Scaffolds via an Enamine-Based Heck Coupling.
Bowen Li, Gregory P Tochtrop

J Org Chem· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Thioredoxin reductase is a major regulator of metabolism in leukemia cells.
Sheelarani Karunanithi, Ruifu Liu, Yongchun Hou, Giancarlo Gonzalez, Natasha Oldford, Gregory P Tochtrop

Oncogene· August 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis of α,β-unsaturated epoxy ketones utilizing a bifunctional sulfonium/phosphonium ylide.
Roozbeh Eskandari, Jeremy P Hess, Gregory P Tochtrop

Chem Commun (Camb)· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy.
Eliav Blum, Jianye Zhang, Jordan Zaluski, David E Einstein, Edward E Korshin, Gregory P Tochtrop

J Med Chem· June 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
Z
Z-isomerization of retinoids through combination of monochromatic photoisomerization and metal catalysis.
Shirin Kahremany, Christopher Lane Sander, Gregory P Tochtrop, Adam Kubas, Krzysztof Palczewski

Org Biomol Chem· September 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Catalytic synthesis of 9-cis-retinoids: mechanistic insights.
Shirin Kahremany, Adam Kubas, Gregory P Tochtrop, Krzysztof Palczewski

Dalton Trans· July 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Progestin therapy to prevent preterm birth: History and effectiveness of current strategies and development of novel approaches.
Sam A Mesiano, Gregory A Peters, Peyvand Amini, Rachel A Wilson, Gregory P Tochtrop

Placenta· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration.
Yuanyuan Chen, Yu Chen, Beata Jastrzebska, Marcin Golczak, Sahil Gulati, Gregory P Tochtrop

Nat Commun· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function.
Philip D Kiser, Jianye Zhang, Aditya Sharma, Juan M Angueyra, Alexander V Kolesnikov, Gregory P Tochtrop

J Gen Physiol· April 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Potent suppression of both spontaneous and carcinogen-induced colitis-associated colorectal cancer in mice by dietary celastrol supplementation.
Emily C Barker, Byung-Gyu Kim, Ji Hee Yoon, Gregory P Tochtrop, John J Letterio

Carcinogenesis· January 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Bile Acid Recognition by Mouse Ileal Bile Acid Binding Protein.
Mohsen Badiee, Gregory P Tochtrop

ACS Chem Biol· December 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inter-relations between 3-hydroxypropionate and propionate metabolism in rat liver: relevance to disorders of propionyl-CoA metabolism.
Kirkland A Wilson, Yong Han, Miaoqi Zhang, Jeremy P Hess, Kimberly A Chapman, Gregory P Tochtrop

Am J Physiol Endocrinol Metab· October 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Rational Tuning of Visual Cycle Modulator Pharmacodynamics.
Philip D Kiser, Jianye Zhang, Mohsen Badiee, Junzo Kinoshita, Neal S Peachey, Gregory P Tochtrop

J Pharmacol Exp Ther· July 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure and Spectroscopy of Alkene-Cleaving Dioxygenases Containing an Atypically Coordinated Non-Heme Iron Center.
Xuewu Sui, Andrew C Weitz, Erik R Farquhar, Mohsen Badiee, Surajit Banerjee, Gregory P Tochtrop

Biochemistry· June 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Photocyclic behavior of rhodopsin induced by an atypical isomerization mechanism.
Sahil Gulati, Beata Jastrzebska, Surajit Banerjee, Ángel L Placeres, Przemyslaw Miszta, Gregory P Tochtrop

Proc Natl Acad Sci U S A· March 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural determinants of ligand binding in the ternary complex of human ileal bile acid binding protein with glycocholate and glycochenodeoxycholate obtained from solution NMR.
Gergő Horváth, Ákos Bencsura, Ágnes Simon, Gregory P Tochtrop, Gregory T DeKoster

FEBS J· February 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
Jianye Zhang, Philip D Kiser, Mohsen Badiee, Grazyna Palczewska, Zhiqian Dong, Gregory P Tochtrop

J Clin Invest· July 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.
Philip D Kiser, Jianye Zhang, Mohsen Badiee, Qingjiang Li, Wuxian Shi, Gregory P Tochtrop

Nat Chem Biol· June 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Catabolism of (2E)-4-hydroxy-2-nonenal via ω- and ω-1-oxidation stimulated by ketogenic diet.
Zhicheng Jin, Jessica M Berthiaume, Qingling Li, Fabrice Henry, Zhong Huang, Gregory P Tochtrop

J Biol Chem· November 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis