Publications by authors named "Gulab Zode"

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Therapeutic mRNA delivery of CRISPR-Cas9 to the trabecular meshwork reverses ocular hypertension in myocilin glaucoma.
Sam Yacoub, Balasankara Reddy Kaipa, Linya Li, Sarahi Rios, Ramesh Kasetti, Gulab S Zode

Mol Ther Methods Clin Dev· December 2025

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TIGER: A tdTomato in vivo genome-editing reporter mouse for investigating precision-editor delivery approaches.
Samuel W Du, Grazyna Palczewska, Zhiqian Dong, Julie C Lauterborn, Balasankara Reddy Kaipa, Gulab Zode

Proc Natl Acad Sci U S A· September 2025

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Genetic and pharmacological correction of impaired mitophagy in retinal ganglion cells rescues glaucomatous neurodegeneration.
Prabhavathi Maddineni, Bindu Kodati, Balasankara Reddy Kaipa, Karthikeyan Kesavan, J Cameron Millar, Gulab S Zode

bioRxiv· February 2025

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C/EBP Homologous Protein Expression in Retinal Ganglion Cells Induces Neurodegeneration in Mice.
William C Mayhew, Balasankara Reddy Kaipa, Linya Li, Prabhavathi Maddineni, Yogapriya Sundaresan, Gulab S Zode

Int J Mol Sci· February 2025

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Impaired axonal transport contributes to neurodegeneration in a Cre-inducible mouse model of myocilin-associated glaucoma.
Balasankara Reddy Kaipa, Ramesh Kasetti, Yogapriya Sundaresan, Linya Li, Sam Yacoub, Gulab S Zode

JCI Insight· January 2025

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A Reduction in Mitophagy Is Associated with Glaucomatous Neurodegeneration in Rodent Models of Glaucoma.
Renuka M Chaphalkar, Bindu Kodati, Prabhavathi Maddineni, Shaoqing He, Calvin D Brooks, Gulab Zode

Int J Mol Sci· December 2024

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Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches.
Ted S Acott, Michael P Fautsch, Weiming Mao, C Ross Ethier, Alex S Huang, Gulab S Zode

Invest Ophthalmol Vis Sci· December 2024

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Impaired axonal transport at the optic nerve head contributes to neurodegeneration in a novel Cre-inducible mouse model of myocilin glaucoma.
Balasankara Reddy Kaipa, Ramesh Kasetti, Yogapriya Sundaresan, Linya Li, Sam Yacoub, Gulab Zode

bioRxiv· November 2024

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Mouse Model of Glucocorticoid-Induced Glaucoma.
Prabhavathi Maddineni, Yogapriya Sundaresan, Gulab Zode

Methods Mol Biol· October 2024

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Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma.
Shruti V Patil, Balasankara Reddy Kaipa, Sujata Ranshing, Yogapriya Sundaresan, J Cameron Millar, Gulab S Zode

Sci Rep· March 2024

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Steroid-Induced Ocular Hypertension in Mice Is Differentially Reduced by Selective EP2, EP3, EP4, and IP Prostanoid Receptor Agonists.
Najam A Sharif, J Cameron Millar, Gulab Zode, Takashi Ota

Int J Mol Sci· March 2024

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Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma.
Shruti V Patil, Balasankara Reddy Kaipa, Sujata Ranshing, Yogapriya Sundaresan, J Cameron Millar, Gulab S Zode

Res Sq· December 2023

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Therapeutic applications of CRISPR/Cas9 gene editing technology for the treatment of ocular diseases.
Yogapriya Sundaresan, Sam Yacoub, Bindu Kodati, Charles E Amankwa, Akash Raola, Gulab Zode

FEBS J· November 2023

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Viral Vector-Induced Ocular Hypertension in Mice.
J Cameron Millar, Yogapriya Sundaresan, Gulab S Zode, Abbot F Clark

Methods Mol Biol· August 2023

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Modulation of Mitochondrial Metabolic Parameters and Antioxidant Enzymes in Healthy and Glaucomatous Trabecular Meshwork Cells with Hybrid Small Molecule SA-2.
Charles E Amankwa, Olivia Young, Biddut DebNath, Sudershan R Gondi, Rajiv Rangan, Gulab Zode

Int J Mol Sci· July 2023

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Neogenin pathway positively regulates fibronectin production by glomerular mesangial cells.
Sarika Chaudhari, Parisa Yazdizadeh Shotorbani, Yu Tao, Ramesh Kasetti, Gulab Zode

Am J Physiol Cell Physiol· July 2022

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Enhanced Orai1-mediated store-operated Ca channel/calpain signaling contributes to high glucose-induced podocyte injury.
Yu Tao, Sarika Chaudhari, Parisa Yazdizadeh Shotorbani, Yanfeng Ding, Zhenglan Chen, Gulab Zode

J Biol Chem· June 2022

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A Novel Mouse Model of TGFβ2-Induced Ocular Hypertension Using Lentiviral Gene Delivery.
Shruti V Patil, Ramesh B Kasetti, J Cameron Millar, Gulab S Zode

Int J Mol Sci· June 2022

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Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms.
Colleen M McDowell, Krishnakumar Kizhatil, Michael H Elliott, Darryl R Overby, Joseph van Batenburg-Sherwood, Gulab Zode

Invest Ophthalmol Vis Sci· February 2022

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Sodium 4-Phenylbutyrate Reduces Ocular Hypertension by Degrading Extracellular Matrix Deposition via Activation of MMP9.
Prabhavathi Maddineni, Ramesh B Kasetti, Bindu Kodati, Sam Yacoub, Gulab S Zode

Int J Mol Sci· September 2021

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GLIS1 regulates trabecular meshwork function and intraocular pressure and is associated with glaucoma in humans.
K Saidas Nair, Chitrangda Srivastava, Robert V Brown, Swanand Koli, Hélène Choquet, Gulab Zode

Nat Commun· August 2021

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Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma.
Pinkal D Patel, Yen-Lin Chen, Ramesh B Kasetti, Prabhavathi Maddineni, William Mayhew, Gulab S Zode

Proc Natl Acad Sci U S A· April 2021

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Caveolar peroxynitrite formation impairs endothelial TRPV4 channels and elevates pulmonary arterial pressure in pulmonary hypertension.
Zdravka Daneva, Corina Marziano, Matteo Ottolini, Yen-Lin Chen, Thomas M Baker, Gulab S Zode

Proc Natl Acad Sci U S A· April 2021

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Autophagy stimulation reduces ocular hypertension in a murine glaucoma model via autophagic degradation of mutant myocilin.
Ramesh B Kasetti, Prabhavathi Maddineni, Charles Kiehlbauch, Shruti Patil, Charles C Searby, Gulab S Zode

JCI Insight· March 2021

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ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load.
Ramesh B Kasetti, Pinkal D Patel, Prabhavathi Maddineni, Shruti Patil, Charles Kiehlbauch, Gulab S Zode

Nat Commun· November 2020

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