Publications by authors named "Guowu Lin"

Claim this Profile
T
Time-Resolved Crystallography Reveals the Mechanisms of GTP hydrolysis for N-RAS and the Oncogenic Mutants G12C, G12V and Q61L.
Guowu Lin, Paola Zinser-Peniche, Xiaohong Zhou, Ulises Santiago, Igor Kurnikov

bioRxiv· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Molecular Basis of Interchain Disulfide Bond Formation in BMP-9 and BMP-10.
Tristin A Schwartze, Stefanie A Morosky, Teresa L Rosato, Amy Henrickson, Guowu Lin

J Mol Biol· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Molecular basis of interchain disulfide-bond formation in BMP-9 and BMP-10.
Tristin A Schwartze, Stefanie A Morosky, Teresa L Rosato, Amy Henrickson, Guowu Lin

bioRxiv· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser.
Guowu Lin, Christopher O Barnes, Simon Weiss, Bercem Dutagaci, Chenxi Qiu

Proc Natl Acad Sci U S A· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Preclinical assessment of a novel human antibody VH domain targeting mesothelin as an antibody-drug conjugate.
Zehua Sun, Xiaojie Chu, Cynthia Adams, Tatiana V Ilina, Michel Guerrero, Guowu Lin

Mol Ther Oncolytics· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural basis of transcription: RNA Polymerase II substrate binding and metal coordination at 3.0 Å using a free-electron laser.
Guowu Lin, Christopher O Barnes, Simon Weiss, Bercem Dutagaci, Chenxi Qiu

bioRxiv· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Detection of Microcrystals for CryoEM.
Simon Weiss, Sandra Vergara, Guowu Lin, Guillermo Calero

Methods Mol Biol· March 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Christopher O Barnes, Ying Wu, Jinhu Song, Guowu Lin, Elizabeth L Baxter

Proc Natl Acad Sci U S A· May 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Transcription with a laser: Radiation-damage-free diffraction of RNA Polymerase II crystals.
Guowu Lin, Simon C Weiss, Sandra Vergara, Carlos Camacho, Guillermo Calero

Methods· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of 4-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-N-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrazole-3-carboxamide (FN-1501), an FLT3- and CDK-Kinase Inhibitor with Potentially High Efficiency against Acute Myelocytic Leukemia.
Yue Wang, Yanle Zhi, Qiaomei Jin, Shuai Lu, Guowu Lin, Jun Ling, Jianlin Jin

J Med Chem· February 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
MicroED Structure of Au(p-MBA) at Subatomic Resolution Reveals a Twinned FCC Cluster.
Sandra Vergara, Dylan A Lukes, Michael W Martynowycz, Ulises Santiago, Germán Plascencia-Villa, Guowu Lin

J Phys Chem Lett· November 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Transmission electron microscopy for the evaluation and optimization of crystal growth.
Hilary P Stevenson, Guowu Lin, Christopher O Barnes, Ieva Sutkeviciute, Troy Krzysiak

Acta Crystallogr D Struct Biol· May 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Christopher O Barnes, Monica Calero, Indranil Malik, Brian W Graham, Henrik Spahr, Guowu Lin

Mol Cell· July 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel 1H-pyrazole-3-carboxamide derivatives: synthesis, anticancer evaluation and identification of their DNA-binding interaction.
Yi Lu, Ting Ran, Guowu Lin, Qiaomei Jin, Jianling Jin

Chem Pharm Bull (Tokyo)· January 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Goniometer-based femtosecond crystallography with X-ray free electron lasers.
Aina E Cohen, S Michael Soltis, Ana González, Laura Aguila, Roberto Alonso-Mori, Guowu Lin, Diling Zhu

Proc Natl Acad Sci U S A· December 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Use of transmission electron microscopy to identify nanocrystals of challenging protein targets.
Hilary P Stevenson, Alexander M Makhov, Monica Calero, Andrea L Edwards, Oliver B Zeldin, Guowu Lin

Proc Natl Acad Sci U S A· June 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and structure of the β-carboline derivatives and their binding intensity with cyclin-dependent kinase 2.
Yue Wang, Qiaomei Jin, Guowu Lin, Taotao Yang, Zhanwei Wang

Chem Pharm Bull (Tokyo)· July 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design, synthesis and biological evaluation of β-carboline derivatives as novel inhibitors targeting B-Raf kinase.
Botao Xin, Weifang Tang, Yue Wang, Guowu Lin, Haichun Liu

Bioorg Med Chem Lett· July 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A selectivity study on mTOR/PI3Kα inhibitors by homology modeling and 3D-QSAR.
Ting Ran, Tao Lu, Haoliang Yuan, Haichun Liu, Jian Wang, Guowu Lin, Shulin Zhuang

J Mol Model· January 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A facile synthesis of 3-substituted 9H-pyrido[3,4-b]indol-1(2H)-one derivatives from 3-substituted beta-carbolines.
Guowu Lin, Yue Wang, Qingfa Zhou, Weifang Tang, Jian Wang

Molecules· August 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
(
(N-{[4-(1,3-benzothiazol-2-yl)anilino]carbonylmethyl-kappaO}iminodiacetato-kappa(3)O,N,O')(1,10-phenanthroline-kappa(2)N,N')cobalt(II) pentahydrate.
Guo-Wu Lin, Yue Wang, Tao Lu

Acta Crystallogr C· April 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
[
[Treatment of second primary malignant tumor induced by radiotherapy].
Guo-hao Wu, Fu-jin Chen, Zong-yuan Zeng, Hao Li, Guo-wu Lin

Zhonghua Zhong Liu Za Zhi· May 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis