Publications by authors named "Qingfa Zhou"

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Discovery of 5-Phenylthiazol-2-amine Derivatives as Novel PI4KIIIβ Inhibitors with Efficacious Antitumor Activity by Inhibiting the PI3K/AKT Axis.
Bichuan Wang, Siyuan Hao, Fang Han, Tianzhi Wu, Shuolei Jia, Qingfa Zhou

J Med Chem· March 2025

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Indolo[3,2-]isoquinoline Hydroxamic Acid Derivatives as Novel Orally Topoisomerase-Histone Deacetylase Dual Inhibitors for NSCLC Therapy.
Bichuan Wang, Ting Shi, Shuolei Jia, Enyuan Wang, Xiuqin Ruan, Qingfa Zhou

J Med Chem· January 2025

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Stabilized Carbon Radical-Mediated Assembly of Arylthianthrenium Salts, Alkenes and Amino Acid/Peptide Derivatives.
Bo Dong, Weiguan Qi, Yifeng Chen, Yufei Zhang, Shiyu Gu, Qingfa Zhou

Adv Sci (Weinh)· January 2025

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Phosphine-Catalyzed [3 + 4] Annulations of Salicylaldehyde Schiff Bases with α-Substituted Allenes: Construction of Functionalized Benzoxepine Fused Succinimide Derivatives.
Ke Wu, Xiuqin Ruan, Quanxin Li, Qihe Jiang, Shaofei Ni, Qingfa Zhou

Org Lett· November 2024

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Discovery of Indolo[3,2-]isoquinoline Derivatives as Novel Top1/2 Dual Inhibitors with Orally Efficacious Antitumor Activity and Low Toxicity.
Bichuan Wang, Shanchao Wu, Shuolei Jia, Xiuqin Ruan, Chunquan Sheng, Qingfa Zhou

J Med Chem· August 2024

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Discovery of novel itaconimide-based derivatives as potent HDAC inhibitors for the efficient treatment of prostate cancer.
Qihe Jiang, Yujiang Tang, Qinglan Hu, Bichuan Wang, Xiuqin Ruan, Qingfa Zhou

Eur J Med Chem· April 2024

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Small molecule modulators of cystic fibrosis transmembrane conductance regulator (CFTR): Structure, classification, and mechanisms.
Luyang Cao, Yong Wu, Yanchun Gong, Qingfa Zhou

Eur J Med Chem· February 2024

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Experimental and Theoretical Study of Phosphine-Catalyzed Reaction Modes in the Reaction of α-Substituted Allenes with Aryl Imines.
Ke Wu, Quanxin Li, Wenbo Su, Shaofei Ni, Qingfa Zhou

Angew Chem Int Ed Engl· December 2023

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Metal-Free Regioselective Hydrophosphorodithioation of Spirovinylcyclopropyl Oxindoles: Rapid Access to Allyl Dialkylphosphorodithioates.
Jiahua Wang, Fang Han, Siyuan Hao, Yu-Jiang Tang, Cheng Xiong, Qingfa Zhou

J Org Chem· October 2022

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An FGFR1-Binding Peptide Modified Liposome for siRNA Delivery in Lung Cancer.
Zhipeng Dong, Yunxue Yin, Jun Luo, Bingxia Li, Fangning Lou, Qingfa Zhou

Int J Mol Sci· July 2022

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Phosphine-Catalyzed Stereoselective Tandem Annulation Reaction for the Synthesis of Chromeno[4,3-]pyrroles.
Zonghao Dai, Jin Zhu, Wenbo Su, Wuxian Zeng, Ziqi Liu, Qingfa Zhou

Org Lett· September 2020

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Iodine-Catalyzed Aerobic Oxidation of Spirovinylcyclopropyl Oxindoles to Form Spiro-1,2-dioxolanes Diastereoselectively.
Cheng Xiong, Kunpeng Cheng, Jiahua Wang, Fulai Yang, Jinrong Lu, Qingfa Zhou

J Org Chem· July 2020

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Catalyst-Free [3+2] Cycloaddition of Electron-Deficient Alkynes and -Hydroxyaryl Azomethine Ylides in Water.
Jin Zhu, Wenbo Su, Cheng Xiong, Ruifang Bai, Qingfa Zhou

ACS Omega· July 2020

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Umpolung of o-Hydroxyaryl Azomethine Ylides: Entry to Functionalized γ-Aminobutyric Acid under Phosphine Catalysis.
Qingqing Chen, Yishu Bao, Xiuqin Yang, Zonghao Dai, Fulai Yang, Qingfa Zhou

Org Lett· September 2018

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Synthesis of functionalized 2,5-dihydropyrrole derivatives via a convenient [3 + 2] annulation of azomethine ylides with allenoates.
Zhusheng Huang, Zonghao Dai, Jin Zhu, Fulai Yang, Qingfa Zhou

Org Biomol Chem· September 2018

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Iodine-Promoted Deoxygenative Iodization/Olefination/Sulfenylation of Ketones with Sulfonyl Hydrazides: Access to β-Iodoalkenyl Sulfides.
Yishu Bao, Xiuqin Yang, Qingfa Zhou, Fulai Yang

Org Lett· April 2018

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Stereoselective Synthesis of Functionalized Benzooxazepino[5,4- a]isoindolone Derivatives via Cesium Carbonate Catalyzed Formal [5 + 2] Annulation of 2-(2-Hydroxyphenyl)isoindoline-1,3-dione with Allenoates.
Chao Yao, Yishu Bao, Tao Lu, Qingfa Zhou

Org Lett· April 2018

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Physiologically stable F127-GO supramolecular hydrogel with sustained drug release characteristic for chemotherapy and photothermal therapy.
Bingxia Li, Luna Zhang, Zichen Zhang, Ruoqing Gao, Hongmei Li, Qingfa Zhou

RSC Adv· January 2018

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Hydroxy-Assisted Regio- and Stereoselective Synthesis of Functionalized 4-Methylenepyrrolidine Derivatives via Phosphine-Catalyzed [3 + 2] Cycloaddition of Allenoates with o-Hydroxyaryl Azomethine Ylides.
Zhusheng Huang, Yishu Bao, Yu Zhang, Fulai Yang, Tao Lu, Qingfa Zhou

J Org Chem· December 2017

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Phosphine-Catalyzed Domino β/γ-Additions of Benzofuranones with Allenoates: A Method for Unsymmetrical 3,3-Disubstituted Benzofuranones.
Zhusheng Huang, Xiuqin Yang, Fulai Yang, Tao Lu, Qingfa Zhou

Org Lett· July 2017

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Phosphine-Catalyzed Intramolecular Cyclizations of α-Nitroethylallenoates Forming (Z)-Furanone Oximes.
Qing-Fa Zhou, Kui Zhang, Lingchao Cai, Ohyun Kwon

Org Lett· June 2016

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Stereoselective Syntheses of α,β-Unsaturated γ-Amino Esters Through Phosphine-Catalyzed γ-Umpolung Additions of Sulfonamides to γ-Substituted Allenoates.
Qing-Fa Zhou, Kui Zhang, Ohyun Kwon

Tetrahedron Lett· June 2015

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Stereoselective synthesis of 3-methyleneisoindolin-1-ones via base-catalyzed intermolecular reactions of electron-deficient alkynes with N-hydroxyphthalimides.
Xin Chen, Fei-Fei Ge, Tao Lu, Qing-Fa Zhou

J Org Chem· March 2015

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Stereoselective syntheses of functionalized spirocyclopenteneoxindoles via triphenylphosphine-catalyzed [3+2] cycloaddition reactions.
Qing-Fa Zhou, Xue-Ping Chu, Fei-Fei Ge, Cheng Li, Tao Lu

Mol Divers· August 2013

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A facile synthesis of 3-substituted 9H-pyrido[3,4-b]indol-1(2H)-one derivatives from 3-substituted beta-carbolines.
Guowu Lin, Yue Wang, Qingfa Zhou, Weifang Tang, Jian Wang

Molecules· August 2010

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