Publications by authors named "Han B Ong"

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Comparative metabolism of conjugated and unconjugated pterins in Crithidia, Leishmania and African trypanosomes.
Han B Ong, Susan Wyllie, Alan H Fairlamb

PLoS Negl Trop Dis· July 2025

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A panel of recombinant cell surface and secreted proteins identifies LdBPK_323600.1 as a serological marker of symptomatic infection.
Adam J Roberts, Han Boon Ong, Simon Clare, Cordelia Brandt, Katherine Harcourt

mBio· May 2024

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Systematic identification of genes encoding cell surface and secreted proteins that are essential for in vitro growth and infection in Leishmania donovani.
Adam J Roberts, Han B Ong, Simon Clare, Cordelia Brandt, Katherine Harcourt

PLoS Pathog· February 2022

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Author Correction: Establishment, optimisation and quantitation of a bioluminescent murine infection model of visceral leishmaniasis for systematic vaccine screening.
Han Boon Ong, Simon Clare, Adam Jonathan Roberts, Mary Edythe Wilson, Gavin James Wright

Sci Rep· April 2021

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Establishment, optimisation and quantitation of a bioluminescent murine infection model of visceral leishmaniasis for systematic vaccine screening.
Han Boon Ong, Simon Clare, Adam Jonathan Roberts, Mary Edythe Wilson, Gavin James Wright

Sci Rep· March 2020

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Characterisation of a putative glutamate 5-kinase from Leishmania donovani.
Natasha Sienkiewicz, Han B Ong, Alan H Fairlamb

FEBS J· July 2018

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The Role of Folate Transport in Antifolate Drug Action in Trypanosoma brucei.
Simon Dewar, Natasha Sienkiewicz, Han B Ong, Richard J Wall, David Horn

J Biol Chem· November 2016

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Trypanosoma brucei DHFR-TS Revisited: Characterisation of a Bifunctional and Highly Unstable Recombinant Dihydrofolate Reductase-Thymidylate Synthase.
Marc W Gibson, Simon Dewar, Han B Ong, Natasha Sienkiewicz, Alan H Fairlamb

PLoS Negl Trop Dis· May 2016

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Genomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African Trypanosome.
Deuan C Jones, Bernardo J Foth, Michael D Urbaniak, Stephen Patterson, Han B Ong

PLoS Negl Trop Dis· December 2015

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Homoserine and quorum-sensing acyl homoserine lactones as alternative sources of threonine: a potential role for homoserine kinase in insect-stage Trypanosoma brucei.
Han B Ong, Wai S Lee, Stephen Patterson, Susan Wyllie, Alan H Fairlamb

Mol Microbiol· January 2015

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Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy.
Han B Ong, Natasha Sienkiewicz, Susan Wyllie, Stephen Patterson, Alan H Fairlamb

Mol Microbiol· October 2013

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Dissecting the metabolic roles of pteridine reductase 1 in Trypanosoma brucei and Leishmania major.
Han B Ong, Natasha Sienkiewicz, Susan Wyllie, Alan H Fairlamb

J Biol Chem· March 2011

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Design, synthesis and biological evaluation of novel inhibitors of Trypanosoma brucei pteridine reductase 1.
Daniel Spinks, Han B Ong, Chidochangu P Mpamhanga, Emma J Shanks, David A Robinson

ChemMedChem· February 2011

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Trypanosoma brucei pteridine reductase 1 is essential for survival in vitro and for virulence in mice.
Natasha Sienkiewicz, Han B Ong, Alan H Fairlamb

Mol Microbiol· August 2010

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Development and validation of a cytochrome c-coupled assay for pteridine reductase 1 and dihydrofolate reductase.
Emma J Shanks, Han B Ong, David A Robinson, Stephen Thompson, Natasha Sienkiewicz

Anal Biochem· January 2010

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