Publications by authors named "Hanfeng Lin"

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Design, Optimization, and Development of RIPK1 Degraders with Improved Pharmacokinetic and Pharmacodynamic Properties.
Dong Lu, Xin Yu, Hanfeng Lin, Ran Cheng, Bin Yang

J Med Chem· November 2025

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COOKIE-Pro: covalent inhibitor binding kinetics profiling on the proteome scale.
Hanfeng Lin, Bin Yang, Lang Ding, Yen-Yu Yang, Matthew V Holt

Nat Commun· September 2025

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Beyond the G-Loop: CRBN Molecular Glues Potently Target VAV1 via a Novel SH3 RT-Loop Degron.
Hanfeng Lin, Xin Yu, Haiyang, Ran Cheng, Xiaoli Qi

bioRxiv· June 2025

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COOKIE-Pro: Covalent Inhibitor Binding Kinetics Profiling on the Proteome Scale.
Hanfeng Lin, Bin Yang, Lang Ding, Yen-Yu Yang, Matthew V Holt

bioRxiv· June 2025

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Development of a RIPK1 degrader to enhance antitumor immunity.
Xin Yu, Dong Lu, Xiaoli Qi, Rishi Ram Paudel, Hanfeng Lin

Nat Commun· December 2024

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Glutathione dynamics in subcellular compartments and implications for drug development.
Hanfeng Lin, Lingfei Wang, Xiqian Jiang, Jin Wang

Curr Opin Chem Biol· August 2024

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Development of a Novel Amplifiable System to Quantify Hydrogen Peroxide in Living Cells.
Lingfei Wang, Hanfeng Lin, Bin Yang, Xiqian Jiang, Jianwei Chen

J Am Chem Soc· August 2024

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Lysineless HiBiT and NanoLuc Tagging Systems as Alternative Tools for Monitoring Targeted Protein Degradation.
Hanfeng Lin, Kristin Riching, May Poh Lai, Dong Lu, Ran Cheng

ACS Med Chem Lett· August 2024

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Development of Biochemical and Cellular Probes to Study RIPK1 Target Engagement.
Xin Yu, Hanfeng Lin, Feng Li, Jin Wang, Dong Lu

ACS Med Chem Lett· June 2024

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Lysineless HiBiT and NanoLuc Tagging Systems as Alternative Tools Monitoring Targeted Protein Degradation.
Hanfeng Lin, Kristin Riching, May Poh Lai, Dong Lu, Ran Cheng

bioRxiv· May 2024

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Development of a First-in-Class RIPK1 Degrader to Enhance Antitumor Immunity.
Jin Wang, Dong Lu, Xin Yu, Xiaoli Qi, Hanfeng Lin

Res Sq· April 2024

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Development of a First-in-Class RIPK1 Degrader to Enhance Antitumor Immunity.
Xin Yu, Dong Lu, Xiaoli Qi, Hanfeng Lin, Bryan L Holloman

bioRxiv· March 2024

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Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops.
Zhizeng Sun, Hanfeng Lin, Liya Hu, Neetu Neetu, Banumathi Sankaran

J Biol Chem· January 2024

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Quantification of glutathione with high throughput live-cell imaging.
Xiaoli Qi, Jianwei Chen, Xiqian Jiang, Dong Lu, Xin Yu, Hanfeng Lin

bioRxiv· July 2023

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Applications of covalent chemistry in targeted protein degradation.
Dong Lu, Xin Yu, Hanfeng Lin, Ran Cheng, Erika Y Monroy

Chem Soc Rev· November 2022

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An active site loop toggles between conformations to control antibiotic hydrolysis and inhibition potency for CTX-M β-lactamase drug-resistance enzymes.
Shuo Lu, Liya Hu, Hanfeng Lin, Allison Judge, Paola Rivera

Nat Commun· November 2022

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Discovery of a potent BTK and IKZF1/3 triple degrader through reversible covalent BTK PROTAC development.
Xin Yu, Wen-Hao Guo, Hanfeng Lin, Ran Cheng, Erika Y Monroy

Curr Res Chem Biol· May 2022

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Suppression of Berberine and Probiotics ( and ) on the Growth of Colon Cancer With Modulation of Gut Microbiota and Butyrate Production.
Chao Huang, Ying Sun, Sheng-Rong Liao, Zhao-Xin Chen, Han-Feng Lin

Front Microbiol· April 2022

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L. Leaves - Integration of Their Transcriptome and Metabolomics Dataset: Investigating Potential Genes Involved in Flavonoid Biosynthesis at Different Harvest Times.
Ding-Qiao Xu, Shu-Yan Cheng, Jun-Qing Zhang, Han-Feng Lin, Yan-Yan Chen

Front Plant Sci· November 2021

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Complete chloroplast genome sequencing support is an independent species from .
Long Wang, Xiangxu Yu, Wenbo Xu, Junqing Zhang, Hanfeng Lin

Physiol Mol Biol Plants· November 2021

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The next steps in academic integrity - education, awareness, norms, duty and law.
Yuehong Helen Zhang, Hanfeng Lin, Xinxin Zhang, Qing Ye

Forensic Sci Res· September 2021

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Integration of full-length transcriptomics and targeted metabolomics to identify benzylisoquinoline alkaloid biosynthetic genes in Corydalis yanhusuo.
Dingqiao Xu, Hanfeng Lin, Yuping Tang, Lu Huang, Jian Xu

Hortic Res· January 2021

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Biodegradation of polyethylene microplastic particles by the fungus Aspergillus flavus from the guts of wax moth Galleria mellonella.
Junqing Zhang, Danling Gao, Quanhao Li, Yixuan Zhao, Li Li, Hanfeng Lin

Sci Total Environ· February 2020

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Identification and Selection of Reference Genes for Quantitative Transcript Analysis in .
Zhenzhen Bao, Kaidi Zhang, Hanfeng Lin, Changjian Li, Xiurong Zhao

Genes (Basel)· January 2020

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Selection and validation of appropriate reference genes for real-time quantitative PCR analysis in Momordica charantia.
Zhenglong Wang, Jiyang Xu, Yihan Liu, Jiyu Chen, Hanfeng Lin

Phytochemistry· August 2019

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