Publications by authors named "Harshil D Dhruv"

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Glioblastoma vulnerability to neddylation inhibition is dependent on PTEN status, and dysregulation of the cell cycle and DNA replication.
Brett Taylor, Nanyun Tang, Yue Hao, Matthew Lee, Sen Peng, Harshil D Dhruv

Neurooncol Adv· June 2024

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PTEN loss drives resistance to the neddylation inhibitor MLN4924 in glioblastoma and can be overcome with TOP2A inhibitors.
Shayesteh R Ferdosi, Brett Taylor, Matthew Lee, Nanyun Tang, Sen Peng, Harshil D Dhruv

Neuro Oncol· November 2022

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Genomic and Phenotypic Characterization of a Broad Panel of Patient-Derived Xenografts Reflects the Diversity of Glioblastoma.
Rachael A Vaubel, Shulan Tian, Dioval Remonde, Mark A Schroeder, Ann C Mladek, Harshil D Dhruv

Clin Cancer Res· March 2020

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Phase 0 Trial of AZD1775 in First-Recurrence Glioblastoma Patients.
Nader Sanai, Jing Li, Julie Boerner, Karri Stark, Jianmei Wu, Harshil D Dhruv

Clin Cancer Res· August 2018

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EGFRvIII-Stat5 Signaling Enhances Glioblastoma Cell Migration and Survival.
Alison Roos, Harshil D Dhruv, Sen Peng, Landon J Inge, Serdar Tuncali

Mol Cancer Res· July 2018

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Evaluation of pre-analytical factors affecting plasma DNA analysis.
Havell Markus, Tania Contente-Cuomo, Maria Farooq, Winnie S Liang, Mitesh J Borad, Harshil D Dhruv

Sci Rep· May 2018

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When the Ends Are Really the Beginnings: Targeting Telomerase for Treatment of GBM.
Saumya R Bollam, Michael E Berens, Harshil D Dhruv

Curr Neurol Neurosci Rep· March 2018

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Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation.
Jonathan B Bell, Frank Eckerdt, Harshil D Dhruv, Darren Finlay, Sen Peng

Mol Cancer Res· January 2018

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Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition.
Matthew J Hangauer, Vasanthi S Viswanathan, Matthew J Ryan, Dhruv Bole, John K Eaton, Harshil D Dhruv

Nature· November 2017

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Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma.
Robert S McNeill, Demitra A Canoutas, Timothy J Stuhlmiller, Harshil D Dhruv, David M Irvin

Neuro Oncol· October 2017

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Genomic profiles of low-grade murine gliomas evolve during progression to glioblastoma.
Mark Vitucci, David M Irvin, Robert S McNeill, Ralf S Schmid, Jeremy M Simon, Harshil D Dhruv

Neuro Oncol· September 2017

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Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway.
Vasanthi S Viswanathan, Matthew J Ryan, Harshil D Dhruv, Shubhroz Gill, Ossia M Eichhoff

Nature· July 2017

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Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells.
Alison Roos, Harshil D Dhruv, Ian T Mathews, Landon J Inge, Serdar Tuncali

Oncotarget· February 2017

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SGEF Is Regulated via TWEAK/Fn14/NF-κB Signaling and Promotes Survival by Modulation of the DNA Repair Response to Temozolomide.
Shannon P Fortin Ensign, Alison Roos, Ian T Mathews, Harshil D Dhruv, Serdar Tuncali

Mol Cancer Res· March 2016

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Propentofylline inhibits glioblastoma cell invasion and survival by targeting the TROY signaling pathway.
Harshil D Dhruv, Alison Roos, Patrick J Tomboc, Serdar Tuncali, Ashley Chavez

J Neurooncol· February 2016

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Intravenous delivery of camptothecin-loaded PLGA nanoparticles for the treatment of intracranial glioma.
Kyle T Householder, Danielle M DiPerna, Eugene P Chung, Gregory M Wohlleb, Harshil D Dhruv

Int J Pharm· February 2015

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Reciprocal activation of transcription factors underlies the dichotomy between proliferation and invasion of glioma cells.
Harshil D Dhruv, Wendy S McDonough Winslow, Brock Armstrong, Serdar Tuncali, Jenny Eschbacher

PLoS One· September 2014

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FN14 expression correlates with MET in NSCLC and promotes MET-driven cell invasion.
Timothy G Whitsett, Shannon P Fortin Ensign, Harshil D Dhruv, Landon J Inge, Paul Kurywchak

Clin Exp Metastasis· August 2014

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Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) promotes glioblastoma cell chemotaxis via Lyn activation.
Harshil D Dhruv, Timothy G Whitsett, Nathan M Jameson, Falak Patel, Jeffrey A Winkles

Carcinogenesis· January 2014

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Molecular determinants of lung cancer metastasis to the central nervous system.
Timothy G Whitsett, Landon J Inge, Harshil D Dhruv, Philip Y Cheung, Glen J Weiss

Transl Lung Cancer Res· August 2013

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Bioresponsive copolymers of poly(N-isopropylacrylamide) with enzyme-dependent lower critical solution temperatures.
Derek J Overstreet, Harshil D Dhruv, Brent L Vernon

Biomacromolecules· May 2010

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