Publications by authors named "Jeffrey A Winkles"

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Post-transcriptional control of HIF-1α by MBNL1 restrains hypoxia-driven stemness in GBM.
Blair P Rendina, Fahim Ahmad, Luka Akerman, Ian Mills, Nina C Lee, Jeffrey A Winkles

Neoplasia· December 2025

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Chimeric switch and inverted cytokine receptors in T cell therapy: reprogramming T cells to overcome immune suppression in the solid tumor microenvironment.
Riley Rane, Fengqiao Li, Alexis Williams, Avaneesh Jayadev, Nhan L Tran, Jeffrey A Winkles

Front Immunol· October 2025

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Fn14-Targeted Gold Nanorods for Augmenting Laser Thermal Therapy for High-Grade Gliomas.
Sumiao Pang, Rebecca J Johnson, Nikhil Pandey, Anshika Kapur, Pavlos Anastasiadis, Jeffrey A Winkles

Langmuir· July 2025

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Toward the scale-up production of polymeric nanotherapeutics for cancer clinical trials.
Md Musavvir Mahmud, Nikhil Pandey, Jeffrey A Winkles, Graeme F Woodworth, Anthony J Kim

Nano Today· June 2024

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Microbubble-Enhanced Focused Ultrasound for Infiltrating Gliomas.
Alexandra A Seas, Adarsha P Malla, Nima Sharifai, Jeffrey A Winkles, Graeme F Woodworth

Biomedicines· June 2024

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Impact of Targeting Moiety Type and Protein Corona Formation on the Uptake of Fn14-Targeted Nanoparticles by Cancer Cells.
Christine P Carney, Nikhil Pandey, Anshika Kapur, Hassan Saadi, Hwei Ling Ong, Jeffrey A Winkles

ACS Nano· October 2023

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Fn14-Directed DART Nanoparticles Selectively Target Neoplastic Cells in Preclinical Models of Triple-Negative Breast Cancer Brain Metastasis.
Christine P Carney, Anshika Kapur, Pavlos Anastasiadis, Rodney M Ritzel, Chixiang Chen, Jeffrey A Winkles

Mol Pharm· January 2023

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DHODH inhibition impedes glioma stem cell proliferation, induces DNA damage, and prolongs survival in orthotopic glioblastoma xenografts.
Raffaella Spina, Ian Mills, Fahim Ahmad, Chixiang Chen, Heather M Ames, Jeffrey A Winkles

Oncogene· December 2022

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Emerging translational approaches for brain cancer therapeutics.
Anthony J Kim, Jeffrey A Winkles, Graeme F Woodworth

Adv Drug Deliv Rev· October 2022

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Nanoparticle-assisted, image-guided laser interstitial thermal therapy for cancer treatment.
Sumiao Pang, Anshika Kapur, Keri Zhou, Pavlos Anastasiadis, Nicholas Ballirano, Jeffrey A Winkles

Wiley Interdiscip Rev Nanomed Nanobiotechnol· September 2022

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Nanotherapeutic treatment of the invasive glioblastoma tumor microenvironment.
Nikhil Pandey, Pavlos Anastasiadis, Christine P Carney, Pranjali P Kanvinde, Graeme F Woodworth, Jeffrey A Winkles

Adv Drug Deliv Rev· September 2022

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Harnessing nanomedicine for enhanced immunotherapy for breast cancer brain metastases.
Christine P Carney, Nikhil Pandey, Anshika Kapur, Graeme F Woodworth, Jeffrey A Winkles

Drug Deliv Transl Res· December 2021

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Leveraging the replication-competent avian-like sarcoma virus/tumor virus receptor-A system for modeling human gliomas.
Pranjali P Kanvinde, Adarsha P Malla, Nina P Connolly, Frank Szulzewsky, Pavlos Anastasiadis, Jeffrey A Winkles

Glia· September 2021

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Elevated fibroblast growth factor-inducible 14 expression transforms proneural-like gliomas into more aggressive and lethal brain cancer.
Nina P Connolly, Rebeca Galisteo, Su Xu, Eli E Bar, Sen Peng, Jeffrey A Winkles

Glia· September 2021

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Therapeutic efficacy and safety of a human fusion construct targeting the TWEAK receptor Fn14 and containing a modified granzyme B.
Ana Alvarez de Cienfuegos, Lawrence H Cheung, Khalid A Mohamedali, Timothy G Whitsett, Jeffrey A Winkles

J Immunother Cancer· September 2020

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Decreased nonspecific adhesivity, receptor-targeted therapeutic nanoparticles for primary and metastatic breast cancer.
Jimena G Dancy, Aniket S Wadajkar, Nina P Connolly, Rebeca Galisteo, Heather M Ames, Jeffrey A Winkles

Sci Adv· January 2020

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Leveraging Surface Plasmon Resonance to Dissect the Interfacial Properties of Nanoparticles: Implications for Tissue Binding and Tumor Penetration.
Aniket S Wadajkar, Jimena G Dancy, Christine P Carney, Brian S Hampton, Heather M Ames, Jeffrey A Winkles

Nanomedicine· August 2019

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Oxaliplatin disrupts pathological features of glioma cells and associated macrophages independent of apoptosis induction.
Nathan B Roberts, Aymen Alqazzaz, Jacqueline R Hwang, Xiulan Qi, Achsah D Keegan, Jeffrey A Winkles

J Neurooncol· December 2018

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Developments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma.
Bryan G Harder, Mylan R Blomquist, Junwen Wang, Anthony J Kim, Graeme F Woodworth, Jeffrey A Winkles

Front Oncol· October 2018

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The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance.
David S Hersh, Bryan G Harder, Alison Roos, Sen Peng, Jonathan E Heath, Jeffrey A Winkles

Neuro Oncol· September 2018

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EGFRvIII-Stat5 Signaling Enhances Glioblastoma Cell Migration and Survival.
Alison Roos, Harshil D Dhruv, Sen Peng, Landon J Inge, Serdar Tuncali, Jeffrey A Winkles

Mol Cancer Res· July 2018

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Differential expression of the TWEAK receptor Fn14 in IDH1 wild-type and mutant gliomas.
David S Hersh, Sen Peng, Jimena G Dancy, Rebeca Galisteo, Jennifer M Eschbacher, Jeffrey A Winkles

J Neurooncol· June 2018

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MR-guided transcranial focused ultrasound safely enhances interstitial dispersion of large polymeric nanoparticles in the living brain.
David S Hersh, Pavlos Anastasiadis, Ali Mohammadabadi, Ben A Nguyen, Sijia Guo, Jeffrey A Winkles

PLoS One· April 2018

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Cross-species transcriptional analysis reveals conserved and host-specific neoplastic processes in mammalian glioma.
Nina P Connolly, Amol C Shetty, Jesse A Stokum, Ina Hoeschele, Marni B Siegel, Jeffrey A Winkles

Sci Rep· January 2018

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Decreased non-specific adhesivity, receptor targeted (DART) nanoparticles exhibit improved dispersion, cellular uptake, and tumor retention in invasive gliomas.
Aniket S Wadajkar, Jimena G Dancy, Nathan B Roberts, Nina P Connolly, Dudley K Strickland, Jeffrey A Winkles

J Control Release· December 2017

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