Publications by authors named "Hartmut Schirok"

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Synthesis of 1,2-Benzothiazine via Nickel-Catalyzed Electrochemical Intramolecular Amination.
Zhao-Ran Liu, Simon Herbert, Hartmut Schirok, Cong Ma, Tian-Sheng Mei

Org Lett· October 2024

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Paired electrolysis-enabled nickel-catalyzed enantioselective reductive cross-coupling between α-chloroesters and aryl bromides.
Dong Liu, Zhao-Ran Liu, Zhen-Hua Wang, Cong Ma, Simon Herbert, Hartmut Schirok

Nat Commun· November 2022

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Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase.
Volker K Schulze, Ulrich Klar, Dirk Kosemund, Antje M Wengner, Gerhard Siemeister, Hartmut Schirok

J Med Chem· August 2020

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Discovery of Rogaratinib (BAY 1163877): a pan-FGFR Inhibitor.
Marie-Pierre Collin, Mario Lobell, Walter Hübsch, Dirk Brohm, Hartmut Schirok

ChemMedChem· March 2018

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Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment of Chronic Heart Failure.
Markus Follmann, Jens Ackerstaff, Gorden Redlich, Frank Wunder, Dieter Lang, Hartmut Schirok

J Med Chem· June 2017

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The chemistry and biology of soluble guanylate cyclase stimulators and activators.
Markus Follmann, Nils Griebenow, Michael G Hahn, Ingo Hartung, Franz-Josef Mais, Hartmut Schirok

Angew Chem Int Ed Engl· September 2013

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Identification of acidic heterocycle-substituted 1H-pyrazolo[3,4-b]pyridines as soluble guanylate cyclase stimulators.
Nils Griebenow, Hartmut Schirok, Joachim Mittendorf, Alexander Straub, Markus Follmann

Bioorg Med Chem Lett· March 2013

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Bay846, a new irreversible small molecule inhibitor of EGFR and Her2, is highly effective against malignant brain tumor models.
Sharon L Longo, David J Padalino, Sandra McGillis, Kirstin Petersen, Hartmut Schirok

Invest New Drugs· December 2012

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Discovery of riociguat (BAY 63-2521): a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension.
Joachim Mittendorf, Stefan Weigand, Cristina Alonso-Alija, Erwin Bischoff, Achim Feurer, Hartmut Schirok

ChemMedChem· May 2009

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Design and synthesis of potent and selective azaindole-based Rho kinase (ROCK) inhibitors.
Hartmut Schirok, Raimund Kast, Santiago Figueroa-Pérez, Samir Bennabi, Mark J Gnoth

ChemMedChem· December 2008

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Microwave-assisted flexible synthesis of 7-azaindoles.
Hartmut Schirok

J Org Chem· July 2006

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Efficient regioselective synthesis of 6-amino-5-benzoyl-1-substituted 2(1H)-pyridinones.
Hartmut Schirok, Cristina Alonso-Alija, Jordi Benet-Buchholz, Andreas H Göller, Rolf Grosser

J Org Chem· November 2005

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On the diastereoselectivity of ru-catalyzed [5 + 2] cycloadditions.
Barry M Trost, Hong C Shen, Tobias Schulz, Christopher Koradin, Hartmut Schirok

Org Lett· October 2003

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