Publications by authors named "Hartmuth Nowak"

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Machine learning identifies clinical sepsis phenotypes that translate to the plasma proteome.
Thilo Bracht, Maike Weber, Kerstin Kappler, Lars Palmowski, Malte Bayer, Hartmuth Nowak

Infection· December 2025

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AIMing for survival: The impact of the free and total AIM concentration in septic patients.
Birte Dyck, Ulrich Bosch Dos Santos, Corinna Müller, Hartmuth Nowak, Tim Rahmel

Front Immunol· November 2025

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Positive suggestions via headphones during general anesthesia for the improvement of vegetative & cognitive postoperative course parameters in elderly orthopedic patients - a randomized controlled double-blinded trial (POSSUDEL).
Lena Heiß, Saskia Neitzert, Ernil Hansen, Hartmuth Nowak, Renate Neitzert

Trials· October 2025

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Plasma proteomics identifies molecular subtypes in sepsis.
Thilo Bracht, Kerstin Kappler, Malte Bayer, Franziska Grell, Karin Schork, Hartmuth Nowak

Crit Care· September 2025

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Computer-Interpretable Quality Indicators for Intensive Care Medicine: Development and Validation Study.
Falk von Dincklage, Viktor Karl Bublitz, Oliver Kumpf, Carlo Jurth, Reimer Riessen, Hartmuth Nowak

J Med Internet Res· September 2025

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Host Biomarkers and Antibiotic Tissue Penetration in Sepsis: Insights from Moxifloxacin.
Maria Sanz-Codina, Hartmuth Nowak, Markus Zeitlinger

Eur J Drug Metab Pharmacokinet· July 2025

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Improving AI-Based Clinical Decision Support Systems and Their Integration Into Care From the Perspective of Experts: Interview Study Among Different Stakeholders.
Godwin Denk Giebel, Pascal Raszke, Hartmuth Nowak, Lars Palmowski, Michael Adamzik

JMIR Med Inform· July 2025

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Impact of glucocorticoid receptor polymorphism rs6198 on sepsis survival in a prospective multicenter cohort.
Christoph Sombetzki, Lars Palmowski, Dominik Ziehe, Hartmuth Nowak, Tim Rahmel

Sci Rep· July 2025

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The protein interaction of mitochondrial transcription factors A and B2 is associated with 30-day survival in critical COVID-19.
Britta Westhus, Patrick Thon, Lars Palmowski, Katharina Rump, Björn Koos, Hartmuth Nowak

Front Immunol· June 2025

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The Actual Clinical Situation Ruthlessly Exposes the Challenge of Rational Care for Nosocomial and Community-Acquired Infections and Requires Even More Efforts for Satisfactory Antibiotic Stewardship.
Hans H Diebner, A Melina Wallrafen, Nina Timmesfeld, Tim Rahmel, Hartmuth Nowak

Antibiotics (Basel)· May 2025

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Subphenotypes and the De Ritis ratio for mortality risk stratification in sepsis-associated acute liver injury: a retrospective cohort study.
Lars Palmowski, Britta Westhus, Andrea Witowski, Hartmuth Nowak, Isabella Traut

EClinicalMedicine· April 2025

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Activation of the MAPK network provides a survival advantage during the course of COVID-19-induced sepsis: a real-world evidence analysis of a multicenter COVID-19 Sepsis Cohort.
Andrea Witowski, Lars Palmowski, Tim Rahmel, Hartmuth Nowak, Stefan F Ehrentraut

Infection· February 2025

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Problems and Barriers Related to the Use of AI-Based Clinical Decision Support Systems: Interview Study.
Godwin Denk Giebel, Pascal Raszke, Hartmuth Nowak, Lars Palmowski, Michael Adamzik

J Med Internet Res· February 2025

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Mortality-associated plasma proteome dynamics in a prospective multicentre sepsis cohort.
Lars Palmowski, Maike Weber, Malte Bayer, Yuxin Mi, Karin Schork, Hartmuth Nowak

EBioMedicine· January 2025

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User-Oriented Requirements for Artificial Intelligence-Based Clinical Decision Support Systems in Sepsis: Protocol for a Multimethod Research Project.
Pascal Raszke, Godwin Denk Giebel, Carina Abels, Jürgen Wasem, Michael Adamzik, Hartmuth Nowak

JMIR Res Protoc· January 2025

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Concentrations of ceftazidime and avibactam in bile fluid-a prospective phase IIb study.
Andrea Witowski, Lars Palmowski, Iris K Minichmayr, Markus Zeitlinger, Christoph Dorn, Hartmuth Nowak

J Antimicrob Chemother· December 2024

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Employing artificial intelligence for optimising antibiotic dosages in sepsis on intensive care unit: a study protocol for a prospective observational study (KI.SEP).
Britta Marko, Lars Palmowski, Hartmuth Nowak, Andrea Witowski, Björn Koos

BMJ Open· December 2024

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High expression of L-GILZ transcript variant 1 (GILZ TV 1) is associated with increased 30-day sepsis mortality, and a high expression ratio possibly contraindicates hydrocortisone administration.
Stefan Rusev, Patrick Thon, Birte Dyck, Dominik Ziehe, Tim Rahmel, Hartmuth Nowak

Crit Care· August 2024

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Predictive enrichment for the need of renal replacement in sepsis-associated acute kidney injury: combination of furosemide stress test and urinary biomarkers TIMP-2 and IGFBP-7.
Lars Palmowski, Simone Lindau, Laura Contreras Henk, Britta Marko, Andrea Witowski, Hartmuth Nowak

Ann Intensive Care· July 2024

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Exploring the relationship between HCMV serostatus and outcomes in COVID-19 sepsis.
Dominik Ziehe, Alexander Wolf, Tim Rahmel, Hartmuth Nowak, Helge Haberl

Front Immunol· May 2024

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Assessing SOFA score trajectories in sepsis using machine learning: A pragmatic approach to improve the accuracy of mortality prediction.
Lars Palmowski, Hartmuth Nowak, Andrea Witowski, Björn Koos, Alexander Wolf

PLoS One· April 2024

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The Association between the rs3747406 Polymorphism in the Glucocorticoid-Induced Leucine Zipper Gene and Sepsis Survivals Depends on the SOFA Score.
Stefan Rusev, Patrick Thon, Tim Rahmel, Dominik Ziehe, Britta Marko, Hartmuth Nowak

Int J Mol Sci· March 2024

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AQP3 and AQP9-Contrary Players in Sepsis?
Patrick Thon, Tim Rahmel, Dominik Ziehe, Lars Palmowski, Britta Marko, Hartmuth Nowak

Int J Mol Sci· January 2024

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The Aquaporin 3 Polymorphism (rs17553719) Is Associated with Sepsis Survival and Correlated with IL-33 Secretion.
Dominik Ziehe, Britta Marko, Patrick Thon, Tim Rahmel, Lars Palmowski, Hartmuth Nowak

Int J Mol Sci· January 2024

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Increased prevalence of clonal hematopoiesis of indeterminate potential in hospitalized patients with COVID-19.
Judith Schenz, Katharina Rump, Benedikt Hermann Siegler, Inga Hemmerling, Tim Rahmel, Hartmuth Nowak

Front Immunol· November 2022

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