Publications by authors named "Tim Rahmel"

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[
[S3 guideline on sepsis-prevention, diagnosis, therapy, and follow-up care-update 2025].
Frank M Brunkhorst, Michael Adamzik, Hubertus Axer, Michael Bauer, Christian Bode, Tim Rahmel

Med Klin Intensivmed Notfmed· December 2025

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Machine learning identifies clinical sepsis phenotypes that translate to the plasma proteome.
Thilo Bracht, Maike Weber, Kerstin Kappler, Lars Palmowski, Malte Bayer, Tim Rahmel

Infection· December 2025

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A preventive care strategy to reduce moderate or severe acute kidney injury after major surgery (BigpAK-2); a multinational, randomised clinical trial.
Alexander Zarbock, Marlies Ostermann, Lui Forni, Christian Bode, Lennart Wild, Tim Rahmel

Lancet· December 2025

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AIMing for survival: The impact of the free and total AIM concentration in septic patients.
Birte Dyck, Ulrich Bosch Dos Santos, Corinna Müller, Hartmuth Nowak, Tim Rahmel

Front Immunol· November 2025

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Plasma proteomics identifies molecular subtypes in sepsis.
Thilo Bracht, Kerstin Kappler, Malte Bayer, Franziska Grell, Karin Schork, Tim Rahmel

Crit Care· September 2025

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Randomised controlled study investigating standard dose continuous renal replacement therapy (CRRT) versus low-dose CRRT in critically ill patients with acute kidney injury (AKI): study protocol for a prospective, randomised, controlled, international, multicentre trial (the 'Ketzerei' trial).
Christian Strauß, Mahan Sadjadi, Thilo von Groote, Hendrik Booke, Ludwig Maximilian Schöne, Tim Rahmel

BMJ Open· September 2025

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Impact of glucocorticoid receptor polymorphism rs6198 on sepsis survival in a prospective multicenter cohort.
Christoph Sombetzki, Lars Palmowski, Dominik Ziehe, Hartmuth Nowak, Tim Rahmel

Sci Rep· July 2025

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The protein interaction of mitochondrial transcription factors A and B2 is associated with 30-day survival in critical COVID-19.
Britta Westhus, Patrick Thon, Lars Palmowski, Katharina Rump, Björn Koos, Tim Rahmel

Front Immunol· June 2025

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The Actual Clinical Situation Ruthlessly Exposes the Challenge of Rational Care for Nosocomial and Community-Acquired Infections and Requires Even More Efforts for Satisfactory Antibiotic Stewardship.
Hans H Diebner, A Melina Wallrafen, Nina Timmesfeld, Tim Rahmel, Hartmuth Nowak

Antibiotics (Basel)· May 2025

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Subphenotypes and the De Ritis ratio for mortality risk stratification in sepsis-associated acute liver injury: a retrospective cohort study.
Lars Palmowski, Britta Westhus, Andrea Witowski, Hartmuth Nowak, Isabella Traut, Tim Rahmel

EClinicalMedicine· April 2025

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Persistent mortality in critical COVID-19 ICU cases from wild-type to delta variant: A descriptive cohort study.
Lars Palmowski, André Hagedorn, Andrea Witowski, Helge Haberl, Felix Kraft, Tim Rahmel

Sci Rep· March 2025

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Activation of the MAPK network provides a survival advantage during the course of COVID-19-induced sepsis: a real-world evidence analysis of a multicenter COVID-19 Sepsis Cohort.
Andrea Witowski, Lars Palmowski, Tim Rahmel, Hartmuth Nowak, Stefan F Ehrentraut

Infection· February 2025

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[Ways to Airway Safety are Changing: S1 Guideline on Airway Management].
Lars Palmowski, Lars Bergmann, Michael Adamzik, Tim Rahmel

Anasthesiol Intensivmed Notfallmed Schmerzther· February 2025

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Mortality-associated plasma proteome dynamics in a prospective multicentre sepsis cohort.
Lars Palmowski, Maike Weber, Malte Bayer, Yuxin Mi, Karin Schork, Tim Rahmel

EBioMedicine· January 2025

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Concentrations of ceftazidime and avibactam in bile fluid-a prospective phase IIb study.
Andrea Witowski, Lars Palmowski, Iris K Minichmayr, Markus Zeitlinger, Christoph Dorn, Tim Rahmel

J Antimicrob Chemother· December 2024

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Employing artificial intelligence for optimising antibiotic dosages in sepsis on intensive care unit: a study protocol for a prospective observational study (KI.SEP).
Britta Marko, Lars Palmowski, Hartmuth Nowak, Andrea Witowski, Björn Koos, Tim Rahmel

BMJ Open· December 2024

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Landiolol for heart rate control in patients with septic shock and persistent tachycardia. A multicenter randomized clinical trial (Landi-SEP).
Sebastian Rehberg, Sandra Frank, Vladimír Černý, Radek Cihlář, Rainer Borgstedt, Tim Rahmel

Intensive Care Med· October 2024

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High expression of L-GILZ transcript variant 1 (GILZ TV 1) is associated with increased 30-day sepsis mortality, and a high expression ratio possibly contraindicates hydrocortisone administration.
Stefan Rusev, Patrick Thon, Birte Dyck, Dominik Ziehe, Tim Rahmel

Crit Care· August 2024

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An open-label, randomized controlled trial to assess a ketogenic diet in critically ill patients with sepsis.
Tim Rahmel, David Effinger, Thilo Bracht, Leonore Griep, Björn Koos

Sci Transl Med· July 2024

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Predictive enrichment for the need of renal replacement in sepsis-associated acute kidney injury: combination of furosemide stress test and urinary biomarkers TIMP-2 and IGFBP-7.
Lars Palmowski, Simone Lindau, Laura Contreras Henk, Britta Marko, Andrea Witowski, Tim Rahmel

Ann Intensive Care· July 2024

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Exploring the relationship between HCMV serostatus and outcomes in COVID-19 sepsis.
Dominik Ziehe, Alexander Wolf, Tim Rahmel, Hartmuth Nowak, Helge Haberl

Front Immunol· May 2024

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Assessing SOFA score trajectories in sepsis using machine learning: A pragmatic approach to improve the accuracy of mortality prediction.
Lars Palmowski, Hartmuth Nowak, Andrea Witowski, Björn Koos, Alexander Wolf, Tim Rahmel

PLoS One· April 2024

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Epirubicin for the Treatment of Sepsis and Septic Shock (EPOS-1): study protocol for a randomised, placebo-controlled phase IIa dose-escalation trial.
Daniel Thomas-Rüddel, Michael Bauer, Luís Ferreira Moita, Christiane Helbig, Peter Schlattmann, Tim Rahmel

BMJ Open· April 2024

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The Association between the rs3747406 Polymorphism in the Glucocorticoid-Induced Leucine Zipper Gene and Sepsis Survivals Depends on the SOFA Score.
Stefan Rusev, Patrick Thon, Tim Rahmel, Dominik Ziehe, Britta Marko

Int J Mol Sci· March 2024

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[Immunometabolism in Sepsis].
Björn Koos, Matthias Unterberg, Tim Rahmel, Michael Adamzik

Anasthesiol Intensivmed Notfallmed Schmerzther· February 2024

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