Publications by authors named "Hayoung Hwang"

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Discovery of the therapeutic potential of PPARδ agonist bearing 1,3,4- thiadiazole in inflammatory disorders.
Jina Kim, Tara Man Kadayat, Jae-Eon Lee, Sugyeong Kwon, Kyungjin Jung, Ji Sun Hwang, Hayoung Hwang

Eur J Med Chem· December 2024

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Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease.
Hyeon Jeong Kim, Haelee Kim, Jaeyoung Song, Jun Young Hong, Elijah Hwejin Lee, Hoosang Hwang, Hayoung Hwang

Theranostics· October 2024

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Engineering small-molecule analogues of altiratinib via CREB-regulated transcription co-activator 3-target screening for the development of potent and safe topical therapeutics against skin hyperpigmentary diseases.
Jeong Hyeon Lee, Hongchan An, HyeJi Kwon, Su-Jeong Lee, Young Hye Park, Ji Sun Hwang, Hayoung Hwang

Clin Transl Med· March 2024

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Exploration of Tetrahydroisoquinoline- and Benzo[]azepine-Based Sphingosine 1-Phosphate Receptor 1 Agonists for the Treatment of Multiple Sclerosis.
Eunji Cha, Jushin Kim, Lizaveta Gotina, Jaehwan Kim, Hyeon Jeong Kim, Hayoung Hwang

J Med Chem· August 2023

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Estrogen-Related Receptor γ Maintains Pancreatic Acinar Cell Function and Identity by Regulating Cellular Metabolism.
Jinhyuk Choi, Tae Gyu Oh, Hee-Won Jung, Kun-Young Park, Hyemi Shin, Hayoung Hwang

Gastroenterology· July 2022

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Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis.
Sun Jun Park, Seul Ki Yeon, Yoowon Kim, Hyeon Jeong Kim, Siwon Kim, Hayoung Hwang

J Med Chem· February 2022

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Trafficking-defective mutant PROKR2 cycles between endoplasmic reticulum and Golgi to attenuate endoplasmic reticulum stress.
Yong Bhum Song, Seung-Yeol Park, Kunyou Park, Hayoung Hwang, Rona S Carroll

Proc Natl Acad Sci U S A· February 2022

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The translocator protein ligands as mitochondrial functional modulators for the potential anti-Alzheimer agents.
TaeHun Kim, Mohammad N Morshed, Ashwini M Londhe, Ji W Lim, Ha E Lee, Hayoung Hwang

J Enzyme Inhib Med Chem· December 2021

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Discovery and Biological Evaluation of -Methyl-pyrrolo[2,3-]pyridine-5-carboxamide Derivatives as JAK1-Selective Inhibitors.
Eunsun Park, Sun Joo Lee, Heegyum Moon, Jongmi Park, Hyeonho Jeon, Ji Sun Hwang, Hayoung Hwang

J Med Chem· January 2021

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An orally available inverse agonist of estrogen-related receptor gamma showed expanded efficacy for the radioiodine therapy of poorly differentiated thyroid cancer.
Jina Kim, Hayoung Hwang, Heeseok Yoon, Jae-Eon Lee, Ji Min Oh

Eur J Med Chem· November 2020

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Nrf2 activator via interference of Nrf2-Keap1 interaction has antioxidant and anti-inflammatory properties in Parkinson's disease animal model.
Siwon Kim, Ambily Nath Indu Viswanath, Jong-Hyun Park, Ha Eun Lee, A Yeong Park, Hayoung Hwang

Neuropharmacology· May 2020

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A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERRγ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer.
Thoudam Debraj Singh, Jaeyoung Song, Jina Kim, Jungwook Chin, Hyun Dong Ji, Hayoung Hwang

Clin Cancer Res· August 2019

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Discovery of BR102375, a new class of non-TZD PPARγ full agonist for the treatment of type 2 diabetes.
Wonken Choung, Deokmo Yang, Hakdo Kim, Hyukjoon Choi, Bo Ram Lee, Hayoung Hwang

Bioorg Med Chem Lett· August 2019

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Discovery of Potent, Selective, and Orally Bioavailable Estrogen-Related Receptor-γ Inverse Agonists To Restore the Sodium Iodide Symporter Function in Anaplastic Thyroid Cancer.
Jina Kim, Jaeyoung Song, Hyun Dong Ji, Eun Kyung Yoo, Jae-Eon Lee, Ji Sun Hwang, Hayoung Hwang

J Med Chem· February 2019

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Saccharoquinoline, a Cytotoxic Alkaloidal Meroterpenoid from Marine-Derived Bacterium sp.
Tu Cam Le, Eun Ju Lee, Jihye Lee, Ahreum Hong, Chae-Yoon Yim, Hayoung Hwang

Mar Drugs· February 2019

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Identification of crizotinib derivatives as potent SHIP2 inhibitors for the treatment of Alzheimer's disease.
Ji Woong Lim, Seok Kyu Kim, Seo Yun Choi, Dong Hoi Kim, Changdev G Gadhe, Hayoung Hwang

Eur J Med Chem· September 2018

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Synthesis and evaluation of an orally available "Y"-shaped biaryl peroxisome proliferator-activated receptor δ agonist.
Dong-Su Kim, Jaehwan Lee, Ashwini M Londhe, Tara Man Kadayat, Jeongmin Joo, Hayoung Hwang

Bioorg Med Chem· August 2018

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Antartin, a Cytotoxic Zizaane-Type Sesquiterpenoid from a sp. Isolated from an Antarctic Marine Sediment.
Dayoung Kim, Eun Ju Lee, Jihye Lee, Alain S Leutou, Yern-Hyerk Shin, Ji Sun Hwang, Hayoung Hwang

Mar Drugs· April 2018

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Scalable Synthesis of Triple-Core-Shell Nanostructures of TiO @MnO @C for High Performance Supercapacitors Using Structure-Guided Combustion Waves.
Dongjoon Shin, Jungho Shin, Taehan Yeo, Hayoung Hwang, Seonghyun Park

Small· March 2018

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Non-targeted metabolomics-guided sildenafil metabolism study in human liver microsomes.
Ju-Hyun Kim, Jun Hyun Jo, Kyung-Ah Seo, Hayoung Hwang, Hye Suk Lee

J Chromatogr B Analyt Technol Biomed Life Sci· January 2018

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Identification of Antiangiogenic Potential and Cellular Mechanisms of Napyradiomycin A1 Isolated from the Marine-Derived Streptomyces sp. YP127.
Ji Sun Hwang, Geum Jin Kim, Hyun Gyu Choi, Min Cheol Kim, Dongyup Hahn, Hayoung Hwang

J Nat Prod· August 2017

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Thermoelectric-pyroelectric hybrid energy generation from thermopower waves in core-shell structured carbon nanotube-PZT nanocomposites.
Taehan Yeo, Hayoung Hwang, Dongjoon Shin, Byungseok Seo, Wonjoon Choi

Nanotechnology· February 2017

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Recent Progress in the Development of Transglutaminase 2 (TGase2) Inhibitors.
Minsoo Song, Hayoung Hwang, Chun Young Im, Soo-Youl Kim

J Med Chem· January 2017

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Thermopower Wave-Driven Hybrid Supercapacitor Charging System.
Dongjoon Shin, Hayoung Hwang, Taehan Yeo, Byungseok Seo, Wonjoon Choi

ACS Appl Mater Interfaces· November 2016

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Insights of a Lead Optimization Study and Biological Evaluation of Novel 4-Hydroxytamoxifen Analogs as Estrogen-Related Receptor γ (ERRγ) Inverse Agonists.
Jina Kim, Seo Yeon Woo, Chun Young Im, Eun Kyung Yoo, Seungmi Lee, Hee-Jong Hwang, Hayoung Hwang, Sung Yeoun Hwang

J Med Chem· November 2016

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