Publications by authors named "Hazel Quek"

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Exploring a patient-specific in vitro pipeline for stratification and drug response prediction of microglia-based therapeutics.
Carla Cuní-López, Romal Stewart, Satomi Okano, Garry L Redlich, Mark W Appleby, Hazel Quek

Sci Rep· March 2025

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The Role of Air Pollution and Olfactory Dysfunction in Alzheimer's Disease Pathogenesis.
Louise Odendaal, Hazel Quek, Carla Cuní-López, Anthony R White, Romal Stewart

Biomedicines· January 2025

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Differential Cytokine Responses of APOE3 and APOE4 Blood-brain Barrier Cell Types to SARS-CoV-2 Spike Proteins.
Juliana C S Chaves, Laura A Milton, Romal Stewart, Tarosi Senapati, Laura M Rantanen, Hazel Quek

J Neuroimmune Pharmacol· May 2024

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Patient-Derived Blood-Brain Barrier Model for Screening Copper Bis(thiosemicarbazone) Complexes as Potential Therapeutics in Alzheimer's Disease.
Joanna M Wasielewska, Kathryn Szostak, Lachlan E McInnes, Hazel Quek, Juliana C S Chaves

ACS Chem Neurosci· April 2024

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Correction: Advanced patient-specific microglia cell models for pre-clinical studies in Alzheimer's disease.
Carla Cuní-López, Romal Stewart, Lotta E Oikari, Tam Hong Nguyen, Tara L Roberts, Hazel Quek

J Neuroinflammation· April 2024

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Advanced patient-specific microglia cell models for pre-clinical studies in Alzheimer's disease.
Carla Cuní-López, Romal Stewart, Lotta E Oikari, Tam Hong Nguyen, Tara L Roberts, Hazel Quek

J Neuroinflammation· February 2024

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Patient-specific monocyte-derived microglia as a screening tool for neurodegenerative diseases.
Hazel Quek, Anthony R White

Neural Regen Res· May 2023

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3D in vitro modelling of human patient microglia: A focus on clinical translation and drug development in neurodegenerative diseases.
Carla Cuní-López, Romal Stewart, Anthony R White, Hazel Quek

J Neuroimmunol· February 2023

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A robust approach to differentiate human monocyte-derived microglia from peripheral blood mononuclear cells.
Hazel Quek, Carla Cuní-López, Romal Stewart, Yi Chieh Lim, Tara L Roberts

STAR Protoc· December 2022

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An Alzheimer's Disease Patient-Derived Olfactory Stem Cell Model Identifies Gene Expression Changes Associated with Cognition.
Laura M Rantanen, Maina Bitar, Riikka Lampinen, Romal Stewart, Hazel Quek

Cells· October 2022

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Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone-Pyridylhydrazone Copper(II) Complex.
Xin Yi Choo, Lachlan E McInnes, Alexandra Grubman, Joanna M Wasielewska, Irina Belaya, Hazel Quek

Int J Mol Sci· September 2022

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Recent Advances in Microglia Modelling to Address Translational Outcomes in Neurodegenerative Diseases.
Carla Cuní-López, Romal Stewart, Hazel Quek, Anthony R White

Cells· May 2022

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ALS monocyte-derived microglia-like cells reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression.
Hazel Quek, Carla Cuní-López, Romal Stewart, Tiziana Colletti, Antonietta Notaro

J Neuroinflammation· February 2022

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Therapeutic Opportunities of Disrupting Genome Integrity in Adult Diffuse Glioma.
Diana Aguilar-Morante, Daniel Gómez-Cabello, Hazel Quek, Tianqing Liu, Petra Hamerlik

Biomedicines· January 2022

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The Role of Chaperone-Mediated Autophagy in Bortezomib Resistant Multiple Myeloma.
Nicholas Nikesitch, Patricia Rebeiro, Lye Lin Ho, Srinivasa Pothula, Xin Maggie Wang, Hazel Quek

Cells· December 2021

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Chronic stress and Alzheimer's disease: the interplay between the hypothalamic-pituitary-adrenal axis, genetics and microglia.
Ayeisha Milligan Armstrong, Tenielle Porter, Hazel Quek, Anthony White, John Haynes

Biol Rev Camb Philos Soc· October 2021

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Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.
Lin Xiao, Klaartje Somers, Jayne Murray, Ruby Pandher, Mawar Karsa, Hazel Quek

Clin Cancer Res· August 2021

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Regulation of RNA degradation pathways during the lipopolysaccharide response in Macrophages.
Hui-Chi Lai, Alexander James, John Luff, Paul De Souza, Hazel Quek

J Leukoc Biol· March 2021

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Altered Brain Endothelial Cell Phenotype from a Familial Alzheimer Mutation and Its Potential Implications for Amyloid Clearance and Drug Delivery.
Lotta E Oikari, Rucha Pandit, Romal Stewart, Carla Cuní-López, Hazel Quek

Stem Cell Reports· May 2020

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Simultaneous targeting of DNA replication and homologous recombination in glioblastoma with a polyether ionophore.
Yi Chieh Lim, Kathleen S Ensbey, Carolin Offenhäuser, Rochelle C J D'souza, Jason K Cullen, Hazel Quek

Neuro Oncol· February 2020

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SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress.
Uda Ho, John Luff, Alexander James, Cheok Soon Lee, Hazel Quek

J Cell Mol Med· December 2019

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Cu(atsm) Attenuates Neuroinflammation.
Xin Yi Choo, Jeffrey R Liddell, Mikko T Huuskonen, Alexandra Grubman, Diane Moujalled, Hazel Quek

Front Neurosci· September 2018

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ATM inhibition prevents interleukin-6 from contributing to the proliferation of glioblastoma cells after ionizing radiation.
Yi Chieh Lim, Hazel Quek, Carolin Offenhäuser, Shazrul Fazry, Andrew Boyd

J Neurooncol· July 2018

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PIKKing a way to regulate inflammation.
Hazel Quek, Yi Chieh Lim, Martin F Lavin, Tara L Roberts

Immunol Cell Biol· January 2018

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A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype.
Hazel Quek, John Luff, KaGeen Cheung, Sergei Kozlov, Magtouf Gatei

Hum Mol Genet· January 2017

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