Publications by authors named "John Luff"

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Regulation of RNA degradation pathways during the lipopolysaccharide response in Macrophages.
Hui-Chi Lai, Alexander James, John Luff, Paul De Souza, Hazel Quek

J Leukoc Biol· March 2021

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SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress.
Uda Ho, John Luff, Alexander James, Cheok Soon Lee, Hazel Quek

J Cell Mol Med· December 2019

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Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage.
Hazel Quek, John Luff, KaGeen Cheung, Sergei Kozlov, Magtouf Gatei

J Leukoc Biol· April 2017

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A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype.
Hazel Quek, John Luff, KaGeen Cheung, Sergei Kozlov, Magtouf Gatei

Hum Mol Genet· January 2017

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Senataxin controls meiotic silencing through ATR activation and chromatin remodeling.
Abrey J Yeo, Olivier J Becherel, John E Luff, Mark E Graham, Derek Richard

Cell Discov· July 2016

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R-loops in proliferating cells but not in the brain: implications for AOA2 and other autosomal recessive ataxias.
Abrey J Yeo, Olivier J Becherel, John E Luff, Jason K Cullen, Thidathip Wongsurawat

PLoS One· January 2015

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Senataxin plays an essential role with DNA damage response proteins in meiotic recombination and gene silencing.
Olivier J Becherel, Abrey J Yeo, Alissa Stellati, Evelyn Y H Heng, John Luff

PLoS Genet· April 2013

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Smg1 haploinsufficiency predisposes to tumor formation and inflammation.
Tara L Roberts, Uda Ho, John Luff, C Soon Lee, Simon H Apte

Proc Natl Acad Sci U S A· January 2013

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Myeloma-induced alloreactive T cells arising in myeloma-infiltrated bones include double-positive CD8+CD4+ T cells: evidence from myeloma-bearing mouse model.
Lisa M Freeman, Alfred Lam, Eugene Petcu, Robert Smith, Ali Salajegheh, John Luff

J Immunol· October 2011

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Dramatic extension of tumor latency and correction of neurobehavioral phenotype in Atm-mutant mice with a nitroxide antioxidant.
Nuri Gueven, John Luff, Cheng Peng, Kazuyuki Hosokawa, Steven E Bottle

Free Radic Biol Med· September 2006

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Regulation of the Atm promoter in vivo.
Nuri Gueven, Toshiyuki Fukao, John Luff, Carol Paterson, Graham Kay

Genes Chromosomes Cancer· January 2006

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Oxidative stress is responsible for deficient survival and dendritogenesis in purkinje neurons from ataxia-telangiectasia mutated mutant mice.
Philip Chen, Cheng Peng, John Luff, Kevin Spring, Dianne Watters

J Neurosci· December 2003

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