Publications by authors named "Hazel Stevens"

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Multi-omics integration at cell type resolution uncovers gene-metabolite mechanisms underlying osteoarthritis heterogeneity.
Abhishek Ojha, Paramita Chatterjee, Linda E Kippner, Hazel Y Stevens, Scott D Boden

bioRxiv· September 2025

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On-chip 3D potency assay for prediction of clinical outcomes for cell therapy candidates for osteoarthritis.
Rebecca S Schneider, Elisa B Nieves, Bhavay Aggarwal, Annie C Bowles-Welch, Hazel Y Stevens

Nat Commun· May 2025

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Single-cell transcriptome and crosstalk analysis reveals immune alterations and key pathways in the bone marrow of knee OA patients.
Paramita Chatterjee, Hazel Y Stevens, Linda E Kippner, Annie C Bowles-Welch, Hicham Drissi

iScience· September 2024

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Mesenchymal Stromal Cell (MSC) Functional Analysis-Macrophage Activation and Polarization Assays.
Hazel Y Stevens, Angela C Jimenez, Bryan Wang, Ye Li, Shivaram Selvam

Bio Protoc· March 2024

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Streamlined Methods for Processing and Cryopreservation of Cell Therapy Products Using Automated Systems.
Ye Li, Hazel Y Stevens, Srikanth Sivaraman, Logan N Porter, Allison R Hoffman

Bio Protoc· December 2023

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Intra-articular delivery of micronized dehydrated human amnion/chorion membrane reduces degenerative changes after onset of post-traumatic osteoarthritis.
Angela S P Lin, David S Reece, Tanushree Thote, Sanjay Sridaran, Hazel Y Stevens

Front Bioeng Biotechnol· September 2023

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Mesenchymal stromal cells for bone trauma, defects, and disease: Considerations for manufacturing, clinical translation, and effective treatments.
Annie C Bowles-Welch, Angela C Jimenez, Hazel Y Stevens, David A Frey Rubio, Linda E Kippner

Bone Rep· June 2023

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Patient-Specific iPSC-Derived Models Link Aberrant Endoplasmic Reticulum Stress Sensing and Response to Juvenile Osteochondritis Dissecans Etiology.
Giuliana E Salazar-Noratto, Catriana C Nations, Hazel Y Stevens, Maojia Xu, Sean Gaynard

Stem Cells Transl Med· May 2023

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Single-cell RNA-seq of out-of-thaw mesenchymal stromal cells shows tissue-of-origin differences and inter-donor cell-cycle variations.
Camila Medrano-Trochez, Paramita Chatterjee, Pallab Pradhan, Hazel Y Stevens, Molly E Ogle

Stem Cell Res Ther· November 2021

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Molecular Crosstalk Between Macrophages and Mesenchymal Stromal Cells.
Hazel Y Stevens, Annie C Bowles, Carolyn Yeago, Krishnendu Roy

Front Cell Dev Biol· December 2020

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Chondroitin Sulfate Glycosaminoglycan Scaffolds for Cell and Recombinant Protein-Based Bone Regeneration.
Seth Andrews, Albert Cheng, Hazel Stevens, Meghan T Logun, Robin Webb

Stem Cells Transl Med· June 2019

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Effects of BMP-2 dose and delivery of microvascular fragments on healing of bone defects with concomitant volumetric muscle loss.
Marissa A Ruehle, Laxminarayanan Krishnan, Casey E Vantucci, Yuyan Wang, Hazel Y Stevens

J Orthop Res· March 2019

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The Effects of Age and Dose on Gene Expression and Segmental Bone Defect Repair After BMP-2 Delivery.
Albert Cheng, Laxminarayanan Krishnan, Lisa Tran, Hazel Y Stevens, Boao Xia

JBMR Plus· February 2019

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Dynamic mass spectrometry probe for electrospray ionization mass spectrometry monitoring of bioreactors for therapeutic cell manufacturing.
Mason A Chilmonczyk, Peter A Kottke, Hazel Y Stevens, Robert E Guldberg, Andrei G Fedorov

Biotechnol Bioeng· January 2019

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Aggregate mesenchymal stem cell delivery ameliorates the regenerative niche for muscle repair.
Marissa A Ruehle, Hazel Y Stevens, Aaron M Beedle, Robert E Guldberg, Jarrod A Call

J Tissue Eng Regen Med· August 2018

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Human platelet lysate supplementation of mesenchymal stromal cell delivery: issues of xenogenicity and species variability.
Ashley B Allen, Emily B Butts, Ian B Copland, Hazel Y Stevens, Robert E Guldberg

J Tissue Eng Regen Med· October 2017

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Skeletal Myoblast-Seeded Vascularized Tissue Scaffolds in the Treatment of a Large Volumetric Muscle Defect in the Rat Biceps Femoris Muscle.
Mon-Tzu Li, Marissa A Ruehle, Hazel Y Stevens, Nick Servies, Nick J Willett

Tissue Eng Part A· September 2017

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Enhanced in vivo retention of low dose BMP-2 via heparin microparticle delivery does not accelerate bone healing in a critically sized femoral defect.
Marian H Hettiaratchi, Tel Rouse, Catherine Chou, Laxminarayanan Krishnan, Hazel Y Stevens

Acta Biomater· September 2017

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Delivery vehicle effects on bone regeneration and heterotopic ossification induced by high dose BMP-2.
Laxminarayanan Krishnan, Lauren B Priddy, Camden Esancy, Brett S Klosterhoff, Hazel Y Stevens

Acta Biomater· February 2017

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Do Surface Porosity and Pore Size Influence Mechanical Properties and Cellular Response to PEEK?
F Brennan Torstrick, Nathan T Evans, Hazel Y Stevens, Ken Gall, Robert E Guldberg

Clin Orthop Relat Res· November 2016

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Osteogenic Differentiation of Mesenchymal Stem Cells by Mimicking the Cellular Niche of the Endochondral Template.
Fiona E Freeman, Hazel Y Stevens, Peter Owens, Robert E Guldberg, Laoise M McNamara

Tissue Eng Part A· October 2016

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Environmental manipulation to promote stem cell survival in vivo: use of aggregation, oxygen carrier, and BMP-2 co-delivery strategies.
Ashley B Allen, Josh A Zimmermann, Olivia A Burnsed, Doron Cohn Yakubovich, Hazel Y Stevens

J Mater Chem B· May 2016

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Effects of in vitro endochondral priming and pre-vascularisation of human MSC cellular aggregates in vivo.
Fiona E Freeman, Ashley B Allen, Hazel Y Stevens, Robert E Guldberg, Laoise M McNamara

Stem Cell Res Ther· November 2015

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Hydrogel-based Delivery of rhBMP-2 Improves Healing of Large Bone Defects Compared With Autograft.
Laxminarayanan Krishnan, Lauren B Priddy, Camden Esancy, Mon-Tzu Alice Li, Hazel Y Stevens

Clin Orthop Relat Res· September 2015

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Effect of cell origin and timing of delivery for stem cell-based bone tissue engineering using biologically functionalized hydrogels.
Christopher R Dosier, Brent A Uhrig, Nick J Willett, Laxminarayanan Krishnan, Mon-Tzu Alice Li, Hazel Y Stevens

Tissue Eng Part A· January 2015

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