Publications by authors named "Heather Durham"

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Targeting lipid droplets in FUS-linked amyotrophic lateral sclerosis mitigates neuronal and astrocytic lipotoxicity.
Laetitia Marcadet, Mari Carmen Pelaez, Antoine Desmeules, Jeanne Serrano, Zhan Cheng, Heather D Durham

Brain· September 2025

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Iridium-Bismuth-Oxide Coatings for Use in Neural Stimulating Electrodes: The Influence of Ir/Bi Ratio.
Xingge Xu, Irshad Ali, Sandra Minotti, Heather D Durham, Sasha Omanovic

J Biomed Mater Res A· July 2025

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Bone Anchored Hearing Aid With Headband Over Cranial Orthosis: A Pilot Study.
Ana E Meza-Rochin, Gwendolyn E Daly, Miracle Uzoekwe, Lyndsay Duffus, Kristin Knight, Heather Durham

Cleft Palate Craniofac J· July 2025

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Localized molecular chaperone synthesis maintains neuronal dendrite proteostasis.
Célia Alecki, Javeria Rizwan, Phuong Le, Suleima Jacob-Tomas, Mario Fernandez Comaduran, Heather D Durham

Nat Commun· December 2024

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Localized synthesis of molecular chaperones sustains neuronal proteostasis.
Celia Alecki, Javeria Rizwan, Phuong Le, Suleima Jacob-Tomas, Mario Fernandez-Comaduran, Heather Durham

bioRxiv· October 2024

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Reversal of cognitive deficits in FUS amyotrophic lateral sclerosis mice by arimoclomol and a class I histone deacetylase inhibitor independent of heat shock protein induction.
Mari Carmen Pelaez, Frédéric Fiore, Nancy Larochelle, Afrooz Dabbaghizadeh, Mario Fernández Comaduran, Heather D Durham

Neurotherapeutics· September 2024

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Impact of histone deacetylase inhibition and arimoclomol on heat shock protein expression and disease biomarkers in primary culture models of familial ALS.
Mario Fernández Comaduran, Sandra Minotti, Suleima Jacob-Tomas, Javeria Rizwan, Nancy Larochelle, Heather D Durham

Cell Stress Chaperones· June 2024

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Localized molecular chaperone synthesis maintains neuronal dendrite proteostasis.
Maria Vera Ugalde, Célia Alecki, Javeria Rizwan, Phuong Le, Suleima Jacob-Tomas, Heather Durham

Res Sq· December 2023

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The J Domain of Sacsin Disrupts Intermediate Filament Assembly.
Afrooz Dabbaghizadeh, Alexandre Paré, Zacharie Cheng-Boivin, Robin Dagher, Sandra Minotti, Heather D Durham

Int J Mol Sci· December 2022

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Editorial: The Role of Heat Shock Proteins in Neuroprotection.
Miklos Santha, Heather D Durham, Laszlo Vigh, Chrisostomos Prodromou

Front Pharmacol· August 2020

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Neurofilaments: neurobiological foundations for biomarker applications.
Arie R Gafson, Nicolas R Barthélemy, Pascale Bomont, Roxana O Carare, Heather D Durham

Brain· July 2020

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Functional Characterization of Neurofilament Light Splicing and Misbalance in Zebrafish.
Doris Lou Demy, Maria Letizia Campanari, Raphael Munoz-Ruiz, Heather D Durham, Benoit J Gentil

Cells· May 2020

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Depending on the stress, histone deacetylase inhibitors act as heat shock protein co-inducers in motor neurons and potentiate arimoclomol, exerting neuroprotection through multiple mechanisms in ALS models.
Rachel Kuta, Nancy Larochelle, Mario Fernandez, Arun Pal, Sandra Minotti, Heather D Durham

Cell Stress Chaperones· January 2020

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Sacsin, mutated in the ataxia ARSACS, regulates intermediate filament assembly and dynamics.
Benoit J Gentil, Gia-Thanh Lai, Marie Menade, Roxanne Larivière, Sandra Minotti, Heather D Durham

FASEB J· February 2019

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TDP-43 regulation of stress granule dynamics in neurodegenerative disease-relevant cell types.
Yousra Khalfallah, Rachel Kuta, Camille Grasmuck, Alexandre Prat, Heather D Durham

Sci Rep· May 2018

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Dysregulation of chromatin remodelling complexes in amyotrophic lateral sclerosis.
Michael Tibshirani, Beibei Zhao, Benoit J Gentil, Sandra Minotti, Christine Marques, Heather D Durham

Hum Mol Genet· November 2017

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A New Mutation in FIG4 Causes a Severe Form of CMT4J Involving TRPV4 in the Pathogenic Cascade.
Benoit J Gentil, Erin O'Ferrall, Colin Chalk, Luis F Santana, Heather D Durham

J Neuropathol Exp Neurol· September 2017

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Altered organization of the intermediate filament cytoskeleton and relocalization of proteostasis modulators in cells lacking the ataxia protein sacsin.
Emma J Duncan, Roxanne Larivière, Teisha Y Bradshaw, Fabiana Longo, Nicolas Sgarioto, Heather D Durham

Hum Mol Genet· August 2017

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Effect of gentamicin and levels of ambient sound on hearing screening outcomes in the neonatal intensive care unit: A pilot study.
Angela C Garinis, Selena Liao, Campbell P Cross, Johnathan Galati, Jessica L Middaugh, Heather Durham

Int J Pediatr Otorhinolaryngol· June 2017

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The central role of heat shock factor 1 in synaptic fidelity and memory consolidation.
Philip L Hooper, Heather D Durham, Zsolt Török, Paul L Hooper, Tim Crul

Cell Stress Chaperones· September 2016

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Neurofilament dynamics and involvement in neurological disorders.
Benoit J Gentil, Michael Tibshirani, Heather D Durham

Cell Tissue Res· June 2015

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Sacs knockout mice present pathophysiological defects underlying autosomal recessive spastic ataxia of Charlevoix-Saguenay.
Roxanne Larivière, Rébecca Gaudet, Benoit J Gentil, Martine Girard, Talita Cristiane Conte, Heather D Durham

Hum Mol Genet· February 2015

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Cytoplasmic sequestration of FUS/TLS associated with ALS alters histone marks through loss of nuclear protein arginine methyltransferase 1.
Michael Tibshirani, Miranda L Tradewell, Katie R Mattina, Sandra Minotti, Wencheng Yang, Heather D Durham

Hum Mol Genet· February 2015

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A two-hybrid screen identifies an unconventional role for the intermediate filament peripherin in regulating the subcellular distribution of the SNAP25-interacting protein, SIP30.
Benoit J Gentil, Jesse R McLean, Shangxi Xiao, Beibei Zhao, Heather D Durham

J Neurochem· December 2014

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The voltage-gated calcium channel blocker lomerizine is neuroprotective in motor neurons expressing mutant SOD1, but not TDP-43.
Luan T Tran, Benoit J Gentil, Kathleen E Sullivan, Heather D Durham

J Neurochem· August 2014

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