Publications by authors named "Heather Judge"

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Pharmacodynamic effects of early aspirin withdrawal after percutaneous coronary intervention in patients with atrial fibrillation treated with ticagrelor or prasugrel.
Mark A Sammut, Mohammed E F Rahman, Claire Bridge, Jessica Hanson, Heather Judge

Platelets· December 2025

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Pre-treatment lysis time of plasma-derived fibrin clots and bleeding in patients on oral anticoagulants for atrial fibrillation in the ARISTOTLE trial.
William A E Parker, Thomas A Nelson, Justin Lee, Heather M Judge, Ramzi A Ajjan

Eur Heart J· May 2025

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Influence of body weight and body mass index on the chronic pharmacokinetic and pharmacodynamic responses to clinically available doses of ticagrelor in patients with chronic coronary syndromes.
William A E Parker, Dominick J Angiolillo, Fabiana Rollini, Francesco Franchi, Marc P Bonaca, Heather M Judge

Vascul Pharmacol· April 2023

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Prolonged enoxaparin therapy compared with standard-of-care antithrombotic therapy in opiate-treated patients undergoing primary percutaneous coronary intervention.
Wael Sumaya, William A E Parker, Heather M Judge, Ian R Hall, Rachel C Orme

Platelets· May 2021

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Offset of ticagrelor prior to coronary artery bypass graft surgery for acute coronary syndromes: effects on platelet function and cellular adenosine uptake.
Kok Weng Ow, William A E Parker, Mark M Porter, Jessica Hanson, Heather M Judge

Platelets· October 2020

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Circulating MicroRNA Levels Indicate Platelet and Leukocyte Activation in Endotoxemia Despite Platelet P2Y Inhibition.
Aitana Braza-Boïls, Temo Barwari, Clemens Gutmann, Mark R Thomas, Heather M Judge

Int J Mol Sci· April 2020

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Very-low-dose twice-daily aspirin maintains platelet inhibition and improves haemostasis during dual-antiplatelet therapy for acute coronary syndrome.
William A E Parker, Rachel C Orme, Jessica Hanson, Hannah M Stokes, Claire M Bridge, Heather M Judge

Platelets· April 2019

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Study of Two Dose Regimens of Ticagrelor Compared With Clopidogrel in Patients Undergoing Percutaneous Coronary Intervention for Stable Coronary Artery Disease.
Rachel C Orme, William A E Parker, Mark R Thomas, Heather M Judge, Kathleen Baster

Circulation· September 2018

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Pharmacodynamic Effects of a 6-Hour Regimen of Enoxaparin in Patients Undergoing Primary Percutaneous Coronary Intervention (PENNY PCI Study).
Wael Sumaya, William A E Parker, Rebekah Fretwell, Ian R Hall, David S Barmby, Heather M Judge

Thromb Haemost· July 2018

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Consistent platelet inhibition with ticagrelor 60 mg twice-daily following myocardial infarction regardless of diabetes status.
Mark R Thomas, Dominick J Angiolillo, Marc P Bonaca, Ramzi A Ajjan, Heather M Judge

Thromb Haemost· May 2017

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Monitoring Antiplatelet Therapy.
Rachel Orme, Heather M Judge, Robert F Storey

Semin Thromb Hemost· April 2017

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Cangrelor inhibits the binding of the active metabolites of clopidogrel and prasugrel to P2Y12 receptors in vitro.
Heather M Judge, Robert J Buckland, Joseph A Jakubowski, Robert F Storey

Platelets· December 2016

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Morphine delays the onset of action of prasugrel in patients with prior history of ST-elevation myocardial infarction.
Mark R Thomas, Allison C Morton, Rashed Hossain, Beining Chen, Lei Luo, Heather M Judge

Thromb Haemost· July 2016

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Platelet Inhibition With Ticagrelor 60 mg Versus 90 mg Twice Daily in the PEGASUS-TIMI 54 Trial.
Robert F Storey, Dominick J Angiolillo, Marc P Bonaca, Mark R Thomas, Heather M Judge

J Am Coll Cardiol· March 2016

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Stability of VerifyNow P2Y12 assay results with citrate anticoagulation as compared to hirudin anticoagulation over 20-min period.
Wael Sumaya, Rajiv R Joshi, Heather M Judge, Rosemary Ecob, Allison C Morton

Platelets· December 2015

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PAR1 antagonists inhibit thrombin-induced platelet activation whilst leaving the PAR4-mediated response intact.
Heather M Judge, Lisa K Jennings, David J Moliterno, Edward Hord, Rosemary Ecob

Platelets· December 2015

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Platelet P2Y12 Inhibitors Reduce Systemic Inflammation and Its Prothrombotic Effects in an Experimental Human Model.
Mark R Thomas, Samuel N Outteridge, Ramzi A Ajjan, Fladia Phoenix, Gurpreet K Sangha, Heather M Judge

Arterioscler Thromb Vasc Biol· December 2015

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Ticagrelor potentiates adenosine-induced stimulation of neutrophil chemotaxis and phagocytosis.
Khalaf F Alsharif, Mark R Thomas, Heather M Judge, Haroon Khan, Lynne R Prince

Vascul Pharmacol· August 2015

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Evolving pattern of platelet P2Y12 inhibition in patients with acute coronary syndromes.
Rajiv R Joshi, Rashed Hossain, Allison C Morton, Rosemary Ecob, Heather M Judge

Platelets· March 2015

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Vessel wall, not platelet, P2Y12 potentiates early atherogenesis.
Laura E West, Tanja Steiner, Heather M Judge, Sheila E Francis, Robert F Storey

Cardiovasc Res· June 2014

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Effects of vorapaxar on platelet reactivity and biomarker expression in non-ST-elevation acute coronary syndromes. The TRACER Pharmacodynamic Substudy.
Robert F Storey, Jayaprakash Kotha, Susan S Smyth, David J Moliterno, Tyrus L Rorick, Heather M Judge

Thromb Haemost· May 2014

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Hirudin anticoagulation allows more rapid determination of P2Y₁₂ inhibition by the VerifyNow P2Y12 assay.
Wael Sumaya, Rebecca L Daly, Sonal Mehra, Amrita J Dhutia, Kate E Howgego, Heather M Judge

Thromb Haemost· March 2013

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Ticagrelor effectively and reversibly blocks murine platelet P2Y12-mediated thrombosis and demonstrates a requirement for sustained P2Y12 inhibition to prevent subsequent neointima.
Shankar B Patil, Laura E Jackman, Sheila E Francis, Heather M Judge, Sven Nylander

Arterioscler Thromb Vasc Biol· December 2010

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Relationship between degree of P2Y12 receptor blockade and inhibition of P2Y12-mediated platelet function.
Heather M Judge, Robert J Buckland, Atsuhiro Sugidachi, Joseph A Jakubowski, Robert F Storey

Thromb Haemost· June 2010

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The active metabolite of prasugrel effectively blocks the platelet P2Y12 receptor and inhibits procoagulant and pro-inflammatory platelet responses.
Heather M Judge, Robert J Buckland, Atsuhiro Sugidachi, Joseph A Jakubowski, Robert F Storey

Platelets· March 2008

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