Publications by authors named "Heather Lynaugh"

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Design of orthogonal constant domain interfaces to aid proper heavy/light chain pairing of bispecific antibodies.
Kyle A Barlow, Michael B Battles, Michael E Brown, Kaleigh Canfield, Xiaojun Lu, Heather Lynaugh

MAbs· December 2025

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Assessing the binding properties of the anti-PD-1 antibody landscape using label-free biosensors.
Michael E Brown, Daniel Bedinger, Asparouh Lilov, Palaniswami Rathanaswami, Maximiliano Vásquez, Heather Lynaugh

PLoS One· June 2020

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Affinity Maturation Enhances Antibody Specificity but Compromises Conformational Stability.
Laila Shehata, Daniel P Maurer, Anna Z Wec, Asparouh Lilov, Elizabeth Champney, Heather Lynaugh

Cell Rep· September 2019

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Deamidation and isomerization liability analysis of 131 clinical-stage antibodies.
Xiaojun Lu, R Paul Nobrega, Heather Lynaugh, Tushar Jain, Kyle Barlow

MAbs· January 2019

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Rapid assessment of oxidation via middle-down LCMS correlates with methionine side-chain solvent-accessible surface area for 121 clinical stage monoclonal antibodies.
Rong Yang, Tushar Jain, Heather Lynaugh, R Paul Nobrega, Xiaojun Lu

MAbs· February 2018

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Purification of common light chain IgG-like bispecific antibodies using highly linear pH gradients.
Beth Sharkey, Sarat Pudi, Ian Wallace Moyer, Lihui Zhong, Bianka Prinz, Heather Lynaugh

MAbs· November 2017

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Database-Centric Method for Automated High-Throughput Deconvolution and Analysis of Kinetic Antibody Screening Data.
R Paul Nobrega, Michael Brown, Cody Williams, Chris Sumner, Patricia Estep, Heather Lynaugh

SLAS Technol· October 2017

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Broad epitope coverage of a human in vitro antibody library.
Arvind Sivasubramanian, Patricia Estep, Heather Lynaugh, Yao Yu, Adam Miles

MAbs· January 2017

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Biophysical properties of the clinical-stage antibody landscape.
Tushar Jain, Tingwan Sun, Stéphanie Durand, Amy Hall, Nga Rewa Houston, Heather Lynaugh

Proc Natl Acad Sci U S A· January 2017

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Target-independent variable region mediated effects on antibody clearance can be FcRn independent.
Ryan L Kelly, Yao Yu, Tingwan Sun, Isabelle Caffry, Heather Lynaugh

MAbs· October 2016

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An alternative assay to hydrophobic interaction chromatography for high-throughput characterization of monoclonal antibodies.
Patricia Estep, Isabelle Caffry, Yao Yu, Tingwan Sun, Yuan Cao, Heather Lynaugh

MAbs· March 2016

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High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in mice.
Ryan L Kelly, Tingwan Sun, Tushar Jain, Isabelle Caffry, Yao Yu, Heather Lynaugh

MAbs· March 2016

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Understanding ForteBio's Sensors for High-Throughput Kinetic and Epitope Screening for Purified Antibodies and Yeast Culture Supernatant.
Yao Yu, Scott Mitchell, Heather Lynaugh, Michael Brown, R Paul Nobrega

J Biomol Screen· January 2016

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Rapid Fc glycosylation analysis of Fc fusions with IdeS and liquid chromatography mass spectrometry.
Heather Lynaugh, Huijuan Li, Bing Gong

MAbs· May 2014

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Elimination of diaminopeptidase activity in Pichia pastoris for therapeutic protein production.
Daniel Hopkins, Sujatha Gomathinayagam, Heather Lynaugh, Terrance A Stadheim, Stephen R Hamilton

Appl Microbiol Biotechnol· March 2014

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O-linked glycosylation analysis of recombinant human granulocyte colony-stimulating factor produced in glycoengineered Pichia pastoris by liquid chromatography and mass spectrometry.
Bing Gong, Irina Burnina, Heather Lynaugh, Huijuan Li

J Chromatogr B Analyt Technol Biomed Life Sci· January 2014

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A cost-effective plate-based sample preparation for antibody N-glycan analysis.
Irina Burnina, Erik Hoyt, Heather Lynaugh, Huijuan Li, Bing Gong

J Chromatogr A· September 2013

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N-glycosylamine-mediated isotope labeling for mass spectrometry-based quantitative analysis of N-linked glycans.
Bing Gong, Erik Hoyt, Heather Lynaugh, Irina Burnina, Renee Moore

Anal Bioanal Chem· July 2013

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High-throughput screening and selection of yeast cell lines expressing monoclonal antibodies.
Gavin C Barnard, Angela R Kull, Nathan S Sharkey, Seemab S Shaikh, Alissa M Rittenhour, Heather Lynaugh

J Ind Microbiol Biotechnol· September 2010

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Production of monoclonal antibodies by glycoengineered Pichia pastoris.
Thomas I Potgieter, Michael Cukan, James E Drummond, Nga Rewa Houston-Cummings, Youwei Jiang, Heather Lynaugh

J Biotechnol· February 2009

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