Publications by authors named "Heather Maecker"

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Exploration of the antibody-drug conjugate clinical landscape.
Heather Maecker, Vidya Jonnalagadda, Sunil Bhakta, Vasu Jammalamadaka, Jagath R Junutula

MAbs· November 2023

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Corrigendum: Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer.
Khaled Ali, Dalya R Soond, Roberto Piñeiro, Thorsten Hagemann, Wayne Pearce, Heather Maecker

Nature· July 2016

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MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade.
Peter J R Ebert, Jeanne Cheung, Yagai Yang, Erin McNamara, Rebecca Hong, Heather Maecker

Immunity· March 2016

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Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer.
Khaled Ali, Dalya R Soond, Roberto Pineiro, Thorsten Hagemann, Wayne Pearce, Heather Maecker

Nature· June 2014

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ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.
Andrew J Souers, Joel D Leverson, Erwin R Boghaert, Scott L Ackler, Nathaniel D Catron, Heather L Maecker

Nat Med· February 2013

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Cellular inhibitors of apoptosis are global regulators of NF-κB and MAPK activation by members of the TNF family of receptors.
Eugene Varfolomeev, Tatiana Goncharov, Heather Maecker, Kerry Zobel, László G Kömüves

Sci Signal· March 2012

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The Bcl-2/Bcl-X(L)/Bcl-w inhibitor, navitoclax, enhances the activity of chemotherapeutic agents in vitro and in vivo.
Jun Chen, Sha Jin, Vivek Abraham, Xiaoli Huang, Bernard Liu, Heather Maecker

Mol Cancer Ther· December 2011

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USP1 deubiquitinates ID proteins to preserve a mesenchymal stem cell program in osteosarcoma.
Samuel A Williams, Heather L Maecker, Dorothy M French, Jinfeng Liu, Andrew Gregg

Cell· September 2011

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Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
Ingrid E Wertz, Saritha Kusam, Cynthia Lam, Toru Okamoto, Wendy Sandoval, Heather Maecker

Nature· March 2011

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Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival.
Martin Schwickart, Xiaodong Huang, Jennie R Lill, Jinfeng Liu, Ronald Ferrando, Heather Maecker

Nature· January 2010

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Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand.
Eugene Varfolomeev, Heather Maecker, Darcie Sharp, David Lawrence, Mark Renz

J Biol Chem· December 2005

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TWEAK attenuates the transition from innate to adaptive immunity.
Heather Maecker, Eugene Varfolomeev, Frank Kischkel, David Lawrence, Heidi LeBlanc

Cell· December 2005

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Epigenetic changes in tumor Fas levels determine immune escape and response to therapy.
Heather L Maecker, Zhong Yun, Holden T Maecker, Amato J Giaccia

Cancer Cell· August 2002

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Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia.
Zhong Yun, Heather L Maecker, Randall S Johnson, Amato J Giaccia

Dev Cell· March 2002

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