Publications by authors named "Hege Christensen"

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A multi-omics microbiome signature is associated with the benefits of gastric bypass surgery and is differentiated from diet induced weight loss through 2 years of follow-up.
Vancheswaran Gopalakrishnan, Chanchal Kumar, Ida Robertsen, Christopher Morehouse, Ben Sparklin, Hege Christensen

Mucosal Immunol· August 2025

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Oral Drug Dosing After Gastric Bypass and Diet-Induced Weight Loss: Simpler Than We Think? Lessons Learned From the COCKTAIL Study.
Kine Eide Kvitne, Jøran Hjelmesæth, Markus Hovd, Rune Sandbu, Line Kristin Johnson, Hege Christensen

Clin Pharmacol Ther· September 2024

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Gastric Bypass vs Diet and Cardiovascular Risk Factors: A Nonrandomized Controlled Trial.
Cecilia Karlsson, Line Kristin Johnson, Peter J Greasley, Kjetil Retterstøl, Jonatan Hedberg, Hege Christensen

JAMA Surg· September 2024

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Digoxin Pharmacokinetics in Patients with Obesity Before and After a Gastric Bypass or a Strict Diet Compared with Normal Weight Individuals.
Kine Eide Kvitne, Markus Hovd, Line Kristin Johnson, Christine Wegler, Cecilia Karlsson, Hege Christensen

Clin Pharmacokinet· January 2024

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Neither Gastric Bypass Surgery Nor Diet-Induced Weight-Loss Affect OATP1B1 Activity as Measured by Rosuvastatin Oral Clearance.
Markus Hovd, Ida Robertsen, Line Kristin Johnson, Veronica Krogstad, Christine Wegler, Hege Christensen

Clin Pharmacokinet· May 2023

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Impact of type 2 diabetes on in vivo activities and protein expressions of cytochrome P450 in patients with obesity.
Kine Eide Kvitne, Anders Åsberg, Line K Johnson, Christine Wegler, Jens K Hertel, Hege Christensen

Clin Transl Sci· November 2022

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Short- and long-term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity.
Kine Eide Kvitne, Veronica Krogstad, Christine Wegler, Line Kristin Johnson, Marianne K Kringen, Hege Christensen

Br J Clin Pharmacol· September 2022

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Correlations between 4β-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range.
Kine Eide Kvitne, Kristine Hole, Veronica Krogstad, Birgit Malene Wollmann, Christine Wegler, Hege Christensen

Eur J Clin Pharmacol· August 2022

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Population pharmacokinetic modeling of CSF to blood clearance: prospective tracer study of 161 patients under work-up for CSF disorders.
Markus Herberg Hovd, Espen Mariussen, Hilde Uggerud, Aslan Lashkarivand, Hege Christensen

Fluids Barriers CNS· July 2022

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Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity.
Christine Wegler, Jacek R Wiśniewski, Ida Robertsen, Hege Christensen, Jens Kristoffer Hertel

Clin Pharmacol Ther· May 2022

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Short- and long-term effects of body weight loss following calorie restriction and gastric bypass on CYP3A-activity - a non-randomized three-armed controlled trial.
Kine Eide Kvitne, Ida Robertsen, Eva Skovlund, Hege Christensen, Veronica Krogstad

Clin Transl Sci· January 2022

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In vitro assessments predict that CYP3A4 contributes to a greater extent than CYP3A5 to prednisolone clearance.
Ragnhild Heier Skauby, Stein Bergan, Anders M Andersen, Nils Tore Vethe, Hege Christensen

Basic Clin Pharmacol Toxicol· December 2021

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Clinical application of intrathecal gadobutrol for assessment of cerebrospinal fluid tracer clearance to blood.
Per K Eide, Espen Mariussen, Hilde Uggerud, Are H Pripp, Aslan Lashkarivand, Hege Christensen

JCI Insight· May 2021

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Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes.
Christine Wegler, Pär Matsson, Veronica Krogstad, Jozef Urdzik, Hege Christensen

Mol Pharm· April 2021

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Correlation of Body Weight and Composition With Hepatic Activities of Cytochrome P450 Enzymes.
Veronica Krogstad, Alexandra Peric, Ida Robertsen, Marianne K Kringen, Maria Vistnes, Hege Christensen

J Pharm Sci· January 2021

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Chronic Inhibition of CYP3A is Temporarily Reduced by Each Hemodialysis Session in Patients With End-Stage Renal Disease.
Erlend Johannessen Egeland, Bartlomiej J Witczak, Hasse Khiabani Zaré, Hege Christensen, Anders Åsberg

Clin Pharmacol Ther· October 2020

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A Comparative Analysis of Cytochrome P450 Activities in Paired Liver and Small Intestinal Samples from Patients with Obesity.
Veronica Krogstad, Alexandra Peric, Ida Robertsen, Marianne K Kringen, Christine Wegler, Hege Christensen

Drug Metab Dispos· January 2020

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Determination of Tacrolimus Concentration and Protein Expression of P-Glycoprotein in Single Human Renal Core Biopsies.
Veronica Krogstad, Nils T Vethe, Ida Robertsen, Grete Hasvold, Anne-Marthe D Ose, Hege Christensen

Ther Drug Monit· June 2018

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Impact of body weight, low energy diet and gastric bypass on drug bioavailability, cardiovascular risk factors and metabolic biomarkers: protocol for an open, non-randomised, three-armed single centre study (COCKTAIL).
Jøran Hjelmesæth, Anders Åsberg, Shalini Andersson, Rune Sandbu, Ida Robertsen, Hege Christensen

BMJ Open· May 2018

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Closer to the Site of Action: Everolimus Concentrations in Peripheral Blood Mononuclear Cells Correlate Well With Whole Blood Concentrations.
Ida Robertsen, Nils Tore Vethe, Karsten Midtvedt, Pål Falck, Hege Christensen

Ther Drug Monit· October 2015

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The influence of CYP3A, PPARA, and POR genetic variants on the pharmacokinetics of tacrolimus and cyclosporine in renal transplant recipients.
Ingrid Lunde, Sara Bremer, Karsten Midtvedt, Beata Mohebi, Miriam Dahl, Hege Christensen

Eur J Clin Pharmacol· June 2014

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Long-term effects of gastric bypass and duodenal switch on systemic exposure of atorvastatin.
Gunn Signe Jakobsen, Ine Blankenberg Skottheim, Rune Sandbu, Hege Christensen, Jo Røislien

Surg Endosc· June 2013

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Endomyocardial, intralymphocyte, and whole blood concentrations of ciclosporin A in heart transplant recipients.
Ida Robertsen, Pål Falck, Arne K Andreassen, Nina K Næss, Niclas Lunder, Hege Christensen

Transplant Res· April 2013

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In vitro inhibition of cytochrome P450 3A4 by Aronia melanocarpa constituents.
Marie Bräunlich, Hege Christensen, Siri Johannesen, Rune Slimestad, Helle Wangensteen

Planta Med· January 2013

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Immunological response as a source to variability in drug metabolism and transport.
Hege Christensen, Monica Hermann

Front Pharmacol· October 2012

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