Publications by authors named "Helen Box"

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Assessment of Favipiravir and Remdesivir in Combination for SARS-CoV-2 Infection in Syrian Golden Hamsters.
Megan Neary, Eduardo Gallardo-Toledo, Joanne Sharp, Joanne Herriott, Edyta Kijak, Helen Box

Viruses· November 2024

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Ronapreve (REGN-CoV; casirivimab and imdevimab) reduces the viral burden and alters the pulmonary response to the SARS-CoV-2 Delta variant (B.1.617.2) in K18-hACE2 mice using an experimental design reflective of a treatment use case.
Lee Tatham, Anja Kipar, Jo Sharp, Edyta Kijak, Joanne Herriott, Helen Box

Microbiol Spectr· August 2024

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evaluation of physicochemical-dependent effects of polymeric nanoparticles on their cellular uptake and co-localization using pulmonary calu-3 cell lines.
Nashwa Osman, Paul Curley, Helen Box, Neill Liptrott, Darren Sexton

Drug Dev Ind Pharm· April 2024

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Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters.
Helen J Box, Joanne Sharp, Shaun H Pennington, Edyta Kijak, Lee Tatham

J Antimicrob Chemother· January 2024

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The experience of hospital care for older surgical patients and their carers: A mixed-methods study.
Janani Thillainadesan, Helen Box, Leanne Kearney, Vasi Naganathan, Michelle Cunich

Australas J Ageing· September 2023

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Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research.
Megan Neary, Usman Arshad, Lee Tatham, Henry Pertinez, Helen Box

J Chromatogr B Analyt Technol Biomed Life Sci· August 2023

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Evaluation of Nafamostat as Chemoprophylaxis for SARS-CoV-2 Infection in Hamsters.
Megan Neary, Joanne Sharp, Eduardo Gallardo-Toledo, Joanne Herriott, Edyta Kijak, Helen Box

Viruses· August 2023

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Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations.
Paul Curley, James J Hobson, Neill J Liptrott, Edward Makarov, Amer Al-Khouja, Helen Box

Pharmaceutics· June 2023

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Ronapreve (REGN-CoV; casirivimab and imdevimab) reduces the viral burden and alters the pulmonary response to the SARS-CoV-2 Delta variant (B.1.617.2) in K18-hACE2 mice using an experimental design reflective of a treatment use case.
Lee Tatham, Anja Kipar, Joanne Sharp, Edyta Kijak, Joanne Herriott, Helen Box

bioRxiv· March 2023

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FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2.
Teresa Brevini, Mailis Maes, Gwilym J Webb, Binu V John, Claudia D Fuchs, Helen Box

Nature· March 2023

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Lack of antiviral activity of probenecid in Vero E6 cells and Syrian golden hamsters: a need for better understanding of inter-lab differences in preclinical assays.
Helen Box, Shaun H Pennington, Edyta Kijak, Lee Tatham, Claire H Caygill

bioRxiv· March 2022

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Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research.
Megan Neary, Usman Arshad, Lee Tatham, Henry Pertinez, Helen Box

bioRxiv· May 2021

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Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.
Rajith K R Rajoli, Henry Pertinez, Usman Arshad, Helen Box, Lee Tatham

Br J Clin Pharmacol· April 2021

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Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection.
James J Hobson, Alison C Savage, Andrew B Dwyer, Catherine Unsworth, Jonathan Massam, Helen Box

Nanoscale· April 2021

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Development of a highly sensitive bioanalytical assay for the quantification of favipiravir.
Paul Curley, Megan Neary, Usman Arshad, Lee Tatham, Henry Pertinez, Helen Box

bioRxiv· February 2021

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Optimisation and validation of a sensitive bioanalytical method for niclosamide.
Usman Arshad, Henry Pertinez, Helen Box, Lee Tatham, Rajith Kr Rajoli

bioRxiv· January 2021

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Prioritization of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics.
Usman Arshad, Henry Pertinez, Helen Box, Lee Tatham, Rajith K R Rajoli

Clin Pharmacol Ther· October 2020

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Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.
Rajith Kr Rajoli, Henry Pertinez, Usman Arshad, Helen Box, Lee Tatham

medRxiv· May 2020

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Pharmacodynamics of Voriconazole for Invasive Pulmonary Scedosporiosis.
Helen Box, Clara Negri, Joanne Livermore, Sarah Whalley, Adam Johnson

Antimicrob Agents Chemother· May 2018

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Pharmacodynamics of the Novel Antifungal Agent F901318 for Acute Sinopulmonary Aspergillosis Caused by Aspergillus flavus.
Clara E Negri, Adam Johnson, Laura McEntee, Helen Box, Sarah Whalley

J Infect Dis· March 2018

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Learning health 'safety' within non-technical skills interprofessional simulation education: a qualitative study.
Morris Gordon, Christopher W R Fell, Helen Box, Michael Farrell, Alison Stewart

Med Educ Online· August 2017

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Efficacy of a Novel Tricyclic Topoisomerase Inhibitor in a Murine Model of Neisseria gonorrhoeae Infection.
Victoria J Savage, Cédric Charrier, Anne-Marie Salisbury, Helen Box, Nathan Chaffer-Malam

Antimicrob Agents Chemother· September 2016

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Unexpected medical undergraduate simulation training (UMUST): can unexpected medical simulation scenarios help prepare medical students for the transition to foundation year doctor?
Simon Watmough, Helen Box, Nick Bennett, Alison Stewart, Michael Farrell

BMC Med Educ· April 2016

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Pharmacodynamics of Isavuconazole in a Dynamic In Vitro Model of Invasive Pulmonary Aspergillosis.
Helen Box, Joanne Livermore, Adam Johnson, Laura McEntee, Timothy W Felton

Antimicrob Agents Chemother· January 2016

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