Publications by authors named "Helen Rollison"

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Survey of Pharmaceutical Industry's Best Practices around In Vitro Transporter Assessment and Implications for Drug Development: Considerations from the International Consortium for Innovation and Quality for Pharmaceutical Development Transporter Working Group.
Helen E Rollison, Pallabi Mitra, Hugues Chanteux, Zhizhou Fang, Xiaomin Liang

Drug Metab Dispos· June 2024

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HepG2 (C3A) spheroids show higher sensitivity compared to HepaRG spheroids for drug-induced liver injury (DILI).
Aneesha Basharat, Helen E Rollison, Dominic P Williams, Delyan P Ivanov

Toxicol Appl Pharmacol· December 2020

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Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells.
Olivia Matthews, Emma E Morrison, John D Tranter, Philip Starkey Lewis, Iqbal S Toor, Helen Rollison

EBioMedicine· December 2020

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Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid.
Alison J Foster, Bhavik Chouhan, Sophie L Regan, Helen Rollison, Sara Amberntsson

Arch Toxicol· April 2019

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Complete Substrate Inhibition of Cytochrome P450 2C8 by AZD9496, an Oral Selective Estrogen Receptor Degrader.
Tashinga E Bapiro, Andy Sykes, Scott Martin, Michael Davies, James W T Yates, Helen E Rollison

Drug Metab Dispos· September 2018

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Effects of Tenapanor on Cytochrome P450-Mediated Drug-Drug Interactions.
Susanne Johansson, David P Rosenbaum, Marie Ahlqvist, Helen Rollison, Mikael Knutsson

Clin Pharmacol Drug Dev· September 2017

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Managing the Risk of CYP3A Induction in Drug Development: A Strategic Approach.
Barry C Jones, Helen Rollison, Susanne Johansson, Kajsa P Kanebratt, Craig Lambert

Drug Metab Dispos· January 2017

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In vitro exploration of potential mechanisms of toxicity of the human hepatotoxic drug fenclozic acid.
Alison V M Rodrigues, Helen E Rollison, Scott Martin, Sunil Sarda, Timothy Schulz-Utermoehl

Arch Toxicol· August 2013

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In vitro hepatic metabolism of cediranib, a potent vascular endothelial growth factor tyrosine kinase inhibitor: interspecies comparison and human enzymology.
Timothy Schulz-Utermoehl, Michael Spear, Christopher R J Pollard, Christine Pattison, Helen Rollison

Drug Metab Dispos· October 2010

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