Publications by authors named "Helena Liang"

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Large-scale drug screening in iPSC-derived motor neurons from sporadic ALS patients identifies a potential combinatorial therapy.
Christopher R Bye, Elizabeth Qian, Katherine Lim, Maciej Daniszewski, Fleur C Garton, Helena H Liang

Nat Neurosci· November 2025

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Growth factor independent 1B is a metabolic regulator that exerts pleiotropic effects on platelet function.
Marie-Christine Morel-Kopp, Marie Levade, Lucinda Beutler, Qiang Chen, Jad Othman, Helena P H Liang

J Thromb Haemost· October 2025

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A semi-automated pipeline for quantifying drusen-like deposits in human induced pluripotent stem cell-derived retinal pigment epithelium cells.
Jenna Hall, Maciej Daniszewski, Shane Cheung, Kalyan Shobhana, Himeesh Kumar, Helena H Liang

SLAS Technol· June 2024

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High throughput functional profiling of genes at intraocular pressure loci reveals distinct networks for glaucoma.
Connor J Greatbatch, Qinyi Lu, Sandy Hung, Alexander J Barnett, Kristof Wing, Helena Liang

Hum Mol Genet· April 2024

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Deep Learning-Based Identification of Intraocular Pressure-Associated Genes Influencing Trabecular Meshwork Cell Morphology.
Connor J Greatbatch, Qinyi Lu, Sandy Hung, Son N Tran, Kristof Wing, Helena Liang

Ophthalmol Sci· March 2024

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A recombinant signalling-selective activated protein C that lacks anticoagulant activity is efficacious and safe in cutaneous wound preclinical models.
Ruilong Zhao, Meilang Xue, Haiyan Lin, Margaret Smith, Helena Liang

Wound Repair Regen· January 2024

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Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration.
Anne Senabouth, Maciej Daniszewski, Grace E Lidgerwood, Helena H Liang, Damián Hernández

Nat Commun· July 2022

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Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma.
Maciej Daniszewski, Anne Senabouth, Helena H Liang, Xikun Han, Grace E Lidgerwood

Cell Genom· June 2022

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Culture Variabilities of Human iPSC-Derived Cerebral Organoids Are a Major Issue for the Modelling of Phenotypes Observed in Alzheimer's Disease.
Damián Hernández, Louise A Rooney, Maciej Daniszewski, Lerna Gulluyan, Helena H Liang

Stem Cell Rev Rep· February 2022

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Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells.
Drew Neavin, Quan Nguyen, Maciej S Daniszewski, Helena H Liang, Han Sheng Chiu

Genome Biol· March 2021

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OXPHOS bioenergetic compensation does not explain disease penetrance in Leber hereditary optic neuropathy.
M Isabel G Lopez Sanchez, Nicole J Van Bergen, Lisa S Kearns, Mark Ziemann, Helena Liang

Mitochondrion· September 2020

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Screening of CRISPR/Cas base editors to target the AMD high-risk Y402H complement factor H variant.
Minh Thuan Nguyen Tran, Mohd Khairul Nizam Mohd Khalid, Alice Pébay, Anthony L Cook, Helena H Liang

Mol Vis· August 2019

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A Need for Better Understanding Is the Major Determinant for Public Perceptions of Human Gene Editing.
Tristan McCaughey, David M Budden, Paul G Sanfilippo, George E C Gooden, Li Fan, Helena Hai Liang

Hum Gene Ther· January 2019

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Single-Cell Profiling Identifies Key Pathways Expressed by iPSCs Cultured in Different Commercial Media.
Maciej Daniszewski, Quan Nguyen, Hun S Chy, Vikrant Singh, Duncan E Crombie, Helena H Liang

iScience· September 2018

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Automated Cell Culture Systems and Their Applications to Human Pluripotent Stem Cell Studies.
Maciej Daniszewski, Duncan E Crombie, Rachael Henderson, Helena H Liang, Raymond C B Wong

SLAS Technol· August 2018

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Role of lysophosphatidic acid in the retinal pigment epithelium and photoreceptors.
Grace E Lidgerwood, Andrew J Morris, Alison Conquest, Maciej Daniszewski, Louise A Rooney, Helena H Liang

Biochim Biophys Acta Mol Cell Biol Lipids· July 2018

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Development of a Modular Automated System for Maintenance and Differentiation of Adherent Human Pluripotent Stem Cells.
Duncan E Crombie, Maciej Daniszewski, Helena H Liang, Tejal Kulkarni, Fan Li

SLAS Discov· September 2017

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Generation of a human induced pluripotent stem cell line CERAi001-A-6 using episomal vectors.
Raymond C B Wong, Sandy S Hung, Stacey Jackson, Vikrant Singh, Shahnaz Khan, Helena H Liang

Stem Cell Res· July 2017

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DNA methylation landscape of ocular tissue relative to matched peripheral blood.
Alex W Hewitt, Vania Januar, Alexandra Sexton-Oates, Jihoon E Joo, Maria Franchina, Helena Liang

Sci Rep· April 2017

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Mitochondrial replacement in an iPSC model of Leber's hereditary optic neuropathy.
Raymond C B Wong, Shiang Y Lim, Sandy S C Hung, Stacey Jackson, Shahnaz Khan, Helena H Liang

Aging (Albany NY)· April 2017

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Inflammation in Chronic Wounds.
Ruilong Zhao, Helena Liang, Elizabeth Clarke, Christopher Jackson, Meilang Xue

Int J Mol Sci· December 2016

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Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells.
Sandy S C Hung, Nicole J Van Bergen, Stacey Jackson, Helena Liang, David A Mackey

Aging (Albany NY)· May 2016

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A Global Social Media Survey of Attitudes to Human Genome Editing.
Tristan McCaughey, Paul G Sanfilippo, George E C Gooden, David M Budden, Li Fan, Helena Hai Liang

Cell Stem Cell· May 2016

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An Interactive Multimedia Approach to Improving Informed Consent for Induced Pluripotent Stem Cell Research.
Tristan McCaughey, Helena H Liang, Christine Chen, Eva Fenwick, Gwyneth Rees

Cell Stem Cell· March 2016

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Electrical Stimulation Promotes Cardiac Differentiation of Human Induced Pluripotent Stem Cells.
Damián Hernández, Rodney Millard, Priyadharshini Sivakumaran, Raymond C B Wong, Duncan E Crombie, Helena Liang

Stem Cells Int· January 2016

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