Publications by authors named "Helena Posteri"

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Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515.
Gianluca Papeo, Paolo Orsini, Nilla R Avanzi, Daniela Borghi, Elena Casale, Helena Posteri

ACS Med Chem Lett· April 2019

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Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy.
Gianluca Papeo, Helena Posteri, Daniela Borghi, Alina A Busel, Francesco Caprera

J Med Chem· September 2015

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Synthesis and SAR of new pyrazolo[4,3-h]quinazoline-3-carboxamide derivatives as potent and selective MPS1 kinase inhibitors.
Marina Caldarelli, Mauro Angiolini, Teresa Disingrini, Daniele Donati, Marco Guanci, Helena Posteri

Bioorg Med Chem Lett· August 2011

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NMS-P937, a 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivative as potent and selective Polo-like kinase 1 inhibitor.
Italo Beria, Roberto T Bossi, Maria Gabriella Brasca, Michele Caruso, Walter Ceccarelli, Helena Posteri

Bioorg Med Chem Lett· May 2011

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4,5-Dihydro-1H-pyrazolo[4,3-h]quinazolines as potent and selective Polo-like kinase 1 (PLK1) inhibitors.
Italo Beria, Barbara Valsasina, Maria Gabriella Brasca, Walter Ceccarelli, Maristella Colombo, Helena Posteri

Bioorg Med Chem Lett· November 2010

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Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors.
Italo Beria, Dario Ballinari, Jay Aaron Bertrand, Daniela Borghi, Roberto Tiberio Bossi, Helena Posteri

J Med Chem· May 2010

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Poly(ADP-ribose) polymerase inhibition in cancer therapy: are we close to maturity?
Gianluca Papeo, Barbara Forte, Paolo Orsini, Claudia Perrera, Helena Posteri

Expert Opin Ther Pat· October 2009

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A new glycociamidine ring precursor: syntheses of (Z)-hymenialdisine, (Z)-2-debromohymenialdisine, and (+/-)-endo-2-debromohymenialdisine.
Gianluca Papeo, Helena Posteri, Daniela Borghi, Mario Varasi

Org Lett· December 2005

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Mimics of ganglioside GM1 as cholera toxin ligands: replacement of the GalNAc residue.
Anna Bernardi, Daniela Arosio, Leonardo Manzoni, Diego Monti, Helena Posteri

Org Biomol Chem· March 2003

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