Publications by authors named "Helene Bon"

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The effect of TG2-inhibitory monoclonal antibody zampilimab on tissue fibrosis in human in vitro and primate in vivo models of chronic kidney disease.
Linghong Huang, Helene Bon, Mabrouka Maamra, Toby Holmes, John Atkinson

PLoS One· May 2024

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Transglutaminase 2: Development of therapeutic antibodies reveals four inhibitory epitopes and confirms extracellular function in fibrotic remodelling.
Mabrouka Maamra, Osama Mehdi Benayad, David Matthews, Catherine Kettleborough, John Atkinson, Helene Bon

Br J Pharmacol· June 2022

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Spontaneous Extracellular Matrix Accumulation in a Human in vitro Model of Renal Fibrosis Is Mediated by αV Integrins.
Hélène Bon, Paul Hales, Simon Lumb, Gill Holdsworth, Tim Johnson

Nephron· September 2020

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Publisher Correction: Quantitative and organisational changes in mature extracellular matrix revealed through high-content imaging of total protein fluorescently stained in situ.
Gill Holdsworth, Hélène Bon, Marianne Bergin, Omar Qureshi, Ross Paveley

Sci Rep· December 2017

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An immunofluorescence assay for extracellular matrix components highlights the role of epithelial cells in producing a stable, fibrillar extracellular matrix.
Omar S Qureshi, Hélène Bon, Breda Twomey, Gill Holdsworth, Kirsty Ford

Biol Open· October 2017

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Quantitative and organisational changes in mature extracellular matrix revealed through high-content imaging of total protein fluorescently stained in situ.
Gill Holdsworth, Hélène Bon, Marianne Bergin, Omar Qureshi, Ross Paveley

Sci Rep· August 2017

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Salt-inducible kinase 2 regulates mitotic progression and transcription in prostate cancer.
Hélène Bon, Karan Wadhwa, Alexander Schreiner, Michelle Osborne, Thomas Carroll

Mol Cancer Res· April 2015

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The ETS family member GABPα modulates androgen receptor signalling and mediates an aggressive phenotype in prostate cancer.
Naomi L Sharma, Charlie E Massie, Falk Butter, Matthias Mann, Helene Bon

Nucleic Acids Res· June 2014

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HES6 drives a critical AR transcriptional programme to induce castration-resistant prostate cancer through activation of an E2F1-mediated cell cycle network.
Antonio Ramos-Montoya, Alastair D Lamb, Roslin Russell, Thomas Carroll, Sarah Jurmeister, Helene Bon

EMBO Mol Med· May 2014

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The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis.
Charles E Massie, Andy Lynch, Antonio Ramos-Montoya, Joan Boren, Rory Stark, Helene Bon

EMBO J· May 2011

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