Publications by authors named "Helin Yu"

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CRISPR-Cas12a2-based rapid and sensitive detection system for target nucleic acid.
Helin Yu, Meng Feng, Chuncao Liu, Feifei Wang, Shaokun Pan

Int J Biol Macromol· February 2025

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Accelerating the speed of innovative anti-tumor drugs to first-in-human trials incorporating key de-risk strategies.
Yuqi Wang, Quan Quan, Camille Gleason, Helin Yu, Lujia Peng, Yue Zheng, Yuanyuan Xie

MAbs· December 2023

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Systematic identification of the lysine lactylation in the protozoan parasite Toxoplasma gondii.
Wei Zhao, Helin Yu, Xiaona Liu, Tingting Wang, Yinning Yao

Parasit Vectors· May 2022

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TgAtg8-TgAtg3 Interaction Primarily Contributes to Apicoplast Inheritance and Parasite Growth in Tachyzoite.
Linyan Cheng, Yuan Tian, Yan Wang, Tingting Wang, Yinning Yao, Helin Yu

Microbiol Spectr· February 2022

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Two old drugs, NVP-AEW541 and GSK-J4, repurposed against the Toxoplasma gondii RH strain.
Shuxian Liu, Mimi Wu, Qianqian Hua, Daiqiang Lu, Yuan Tian, Helin Yu

Parasit Vectors· May 2020

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Conjugation of DM1 to anti-CD30 antibody has potential antitumor activity in CD30-positive hematological malignancies with lower systemic toxicity.
Yijun Shen, Tong Yang, Xuemei Cao, Yifan Zhang, Li Zhao, Helin Yu, Lingyu Guan

MAbs· January 2020

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Three transcriptional regulators positively regulate the biosynthesis of polycyclic tetramate macrolactams in Streptomyces xiamenensis 318.
Xu-Liang Bu, Jing-Yi Weng, He-Lin Yu, Min-Juan Xu, Jun Xu

Appl Microbiol Biotechnol· January 2020

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Correction to: 'Dynamical modelling of secondary metabolism and metabolic switches in 318'.
Xiao-Mei Zhu, Xing-Xing Zhang, Run-Tan Cheng, He-Lin Yu, Ruo-Shi Yuan

R Soc Open Sci· June 2019

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Dynamical modelling of secondary metabolism and metabolic switches in 318.
Xiao-Mei Zhu, Xing-Xing Zhang, Run-Tan Cheng, He-Lin Yu, Ruo-Shi Yuan

R Soc Open Sci· April 2019

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Structural diversity of anti-pancreatic cancer capsimycins identified in mangrove-derived Streptomyces xiamenensis 318 and post-modification via a novel cytochrome P450 monooxygenase.
He-Lin Yu, Shu-Heng Jiang, Xu-Liang Bu, Jia-Hua Wang, Jing-Yi Weng

Sci Rep· January 2017

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Endogenous network states predict gain or loss of functions for genetic mutations in hepatocellular carcinoma.
Gaowei Wang, Hang Su, Helin Yu, Ruoshi Yuan, Xiaomei Zhu

J R Soc Interface· February 2016

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Deciphering the streamlined genome of Streptomyces xiamenensis 318 as the producer of the anti-fibrotic drug candidate xiamenmycin.
Min-Juan Xu, Jia-Hua Wang, Xu-Liang Bu, He-Lin Yu, Peng Li, Hong-Yu Ou

Sci Rep· January 2016

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