Publications by authors named "Helmout Modjtahedi"

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Advancements in Targeted Therapies for Colorectal Cancer: Overcoming Challenges and Exploring Future Directions.
Said A Khelwatty, Soozana Puvanenthiran, Alan M Seddon, Izhar Bagwan, Sharadah Essapen, Helmout Modjtahedi

Cancers (Basel)· August 2025

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Co-expression of HER2/EGFRvIII/CD44 and Claudin 18.2/CD109 as Novel Prognostic Indicators in Stomach Adenocarcinoma.
Tina Al Janaby, Said Khelwatty, Izhar Bagwan, Nima Abbassi-Ghadi, Helmout Modjtahedi

World J Oncol· June 2025

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The Co-Expression and Cellular Location of HER Family Members, EGFRvIII, Putative Cancer Stem Cell Biomarkers CD44 and CD109 in Patients with Glioblastoma, and Their Impacts on Prognosis.
Ermira Mulliqi, Said Khelwatty, Izhar Bagwan, Ahmad Kamaludin, Anna Morgan, Helmout Modjtahedi

Cancers (Basel)· April 2025

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Development and Characterization of Three Novel FGFR Inhibitor Resistant Cervical Cancer Cell Lines to Help Drive Cervical Cancer Research.
Nauf Bou Antoun, Hiba-Tun-Noor Afshan Mahmood, Anthony J Walker, Helmout Modjtahedi, Richard P Grose

Int J Mol Sci· February 2025

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Expression of EGFRvIII and its co‑expression with wild‑type EGFR, or putative cancer stem cell biomarkers CD44 or EpCAM are associated with poorer prognosis in patients with hepatocellular carcinoma.
Ozlem Sherif, Said A Khelwatty, Izhar Bagwan, Alan M Seddon, Angus Dalgleish, Helmout Modjtahedi

Oncol Rep· December 2024

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Synergistic Effects of Neratinib in Combination With Palbociclib or Miransertib in Brain Cancer Cells.
Ermira Mulliqi, Said Khelwatty, Anna Morgan, Keyoumars Ashkan, Helmout Modjtahedi

World J Oncol· June 2024

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The Combination of Afatinib With Dasatinib or Miransertib Results in Synergistic Growth Inhibition of Stomach Cancer Cells.
Tina Al-Janaby, Narmin Nahi, Alan Seddon, Izhar Bagwan, Said Khelwatty, Helmout Modjtahedi

World J Oncol· April 2024

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Description of PTPRG genetic variants identified in a cohort of Chronic Myeloid Leukemia patients and their ability to influence response to Tyrosine kinase Inhibitors.
Mohamed A Ismail, Gheyath K Nasrallah, Maria Monne, Ali AlSayab, Mohamed A Yassin, Helmout Modjtahedi

Gene· March 2022

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Cytokine/Chemokine Release Patterns and Transcriptomic Profiles of LPS/IFNγ-Activated Human Macrophages Differentiated with Heat-Killed , M-CSF, or GM-CSF.
Samer Bazzi, Emale El-Darzi, Tina McDowell, Helmout Modjtahedi, Satvinder Mudan

Int J Mol Sci· July 2021

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Predictive value of tyrosine phosphatase receptor gamma for the response to treatment tyrosine kinase inhibitors in chronic myeloid leukemia patients.
Mohamed A Ismail, Marzia Vezzalini, Hisham Morsi, Ahmad Abujaber, Ali Al Sayab, Helmout Modjtahedi

Sci Rep· April 2021

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Therapeutic Application of Monoclonal Antibodies in Pancreatic Cancer: Advances, Challenges and Future Opportunities.
Gustavo A Arias-Pinilla, Helmout Modjtahedi

Cancers (Basel)· April 2021

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HER2 Expression Is Predictive of Survival in Cetuximab Treated Patients with Wild Type Metastatic Colorectal Cancer.
Said A Khelwatty, Soozana Puvanenthiran, Sharadah Essapen, Izhar Bagwan, Alan M Seddon, Helmout Modjtahedi

Cancers (Basel)· February 2021

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Synergistic activity of agents targeting growth factor receptors, CDKs and downstream signaling molecules in a panel of pancreatic cancer cell lines and the identification of antagonistic combinations: Implications for future clinical trials in pancreatic cancer.
Tanzeel Khan, Alan M Seddon, Angus G Dalgleish, Said Khelwatty, Nikolaos Ioannou, Helmout Modjtahedi

Oncol Rep· December 2020

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Aberrant DNA methylation of PTPRG as one possible mechanism of its under-expression in CML patients in the State of Qatar.
Mohamed A Ismail, Muthanna Samara, Ali Al Sayab, Mohamed Alsharshani, Mohamed A Yassin, Helmout Modjtahedi

Mol Genet Genomic Med· October 2020

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Development and application of two novel monoclonal antibodies against overexpressed CD26 and integrin α3 in human pancreatic cancer.
Gustavo A Arias-Pinilla, Angus G Dalgleish, Satvinder Mudan, Izhar Bagwan, Anthony J Walker, Helmout Modjtahedi

Sci Rep· January 2020

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Co-expression and prognostic significance of putative CSC markers CD44, CD133, wild-type EGFR and EGFRvIII in metastatic colorectal cancer.
Said Abdullah Khelwatty, Sharadah Essapen, Izhar Bagwan, Margaret Green, Alan M Seddon, Helmout Modjtahedi

Oncotarget· March 2019

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Construction of a Recombinant Phage-vaccine Capable of Reducing the Growth Rate of an Established LL2 Tumor Model.
Majid Asadi-Ghalehni, Mohamad Javad Rasaee, Nabiollah Namvar Asl, Masood Khosravani, Masoumeh Rajabibazl, Helmout Modjtahedi

Iran J Allergy Asthma Immunol· June 2018

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Co-expression and prognostic significance of the HER family members, EGFRvIII, c-MET, CD44 in patients with ovarian cancer.
Soozana Puvanenthiran, Sharadah Essapen, Ben Haagsma, Izhar Bagwan, Margaret Green, Helmout Modjtahedi

Oncotarget· April 2018

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Development of novel monoclonal antibodies against CD109 overexpressed in human pancreatic cancer.
Gustavo A Arias-Pinilla, Angus G Dalgleish, Satvinder Mudan, Izhar Bagwan, Anthony J Walker, Helmout Modjtahedi

Oncotarget· April 2018

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Targeted delivery of doxorubicin into tumor cells by nanostructured lipid carriers conjugated to anti-EGFRvIII monoclonal antibody.
Saeideh Abdolahpour, Tayebeh Toliyat, Kobra Omidfar, Helmout Modjtahedi, Albert J Wong

Artif Cells Nanomed Biotechnol· February 2018

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A novel recombinant anti-epidermal growth factor receptor peptide vaccine capable of active immunization and reduction of tumor volume in a mouse model.
Majid Asadi-Ghalehni, Mohamad Javad Rasaee, Masoumeh RajabiBazl, Masood Khosravani, Majid Motaghinejad, Helmout Modjtahedi

Microbiol Immunol· December 2017

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Immunomodulatory effects of heat-killed Mycobacterium obuense on human blood dendritic cells.
Samer Bazzi, Helmout Modjtahedi, Satvinder Mudan, Marcel Achkar, Charles Akle

Innate Immun· October 2017

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Defining Genome-Wide Expression and Phenotypic Contextual Cues in Macrophages Generated by Granulocyte/Macrophage Colony-Stimulating Factor, Macrophage Colony-Stimulating Factor, and Heat-Killed Mycobacteria.
Samer Bazzi, Emale El-Darzi, Tina McDowell, Helmout Modjtahedi, Satvinder Mudan

Front Immunol· October 2017

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Inhibitory Effects of Culinary Herbs and Spices on the Growth of HCA-7 Colorectal Cancer Cells and Their COX-2 Expression.
Andrius Jaksevicius, Mark Carew, Calli Mistry, Helmout Modjtahedi, Elizabeth I Opara

Nutrients· September 2017

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Synergistic effects of various Her inhibitors in combination with IGF-1R, C-MET and Src targeting agents in breast cancer cell lines.
Aryan Stanley, G Hossein Ashrafi, Alan M Seddon, Helmout Modjtahedi

Sci Rep· June 2017

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