Publications by authors named "Helmut Jonuleit"

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Impaired PTEN Expression in T Cells Drives Resistance to Treg-Mediated Immune Regulation in Multiple Sclerosis.
Janine Schlöder, Bettina Trinschek, Felix Luessi, Helmut Jonuleit

Cells· September 2025

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ERK5 modulates IL-6 secretion and contributes to tumor-induced immune suppression.
Kristina Riegel, Hajime Yurugi, Janine Schlöder, Helmut Jonuleit, Manuel Kaulich

Cell Death Dis· October 2021

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Novel anti-GARP antibody DS-1055a augments anti-tumor immunity by depleting highly suppressive GARP+ regulatory T cells.
Kazuki Satoh, Yoichi Kobayashi, Kaori Fujimaki, Shinko Hayashi, Saori Ishida, Helmut Jonuleit

Int Immunol· July 2021

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ERK3/MAPK6 is required for KRAS-mediated NSCLC tumorigenesis.
Katarzyna Bogucka, Federico Marini, Sebastian Rosigkeit, Janine Schloeder, Helmut Jonuleit

Cancer Gene Ther· May 2021

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Correction: ERK3/MAPK6 is required for KRAS-mediated NSCLC tumorigenesis.
Katarzyna Bogucka, Federico Marini, Sebastian Rosigkeit, Janine Schloeder, Helmut Jonuleit

Cancer Gene Ther· May 2021

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In-Depth Immune-Oncology Studies of the Tumor Microenvironment in a Humanized Melanoma Mouse Model.
Jonathan Schupp, Arne Christians, Niklas Zimmer, Lukas Gleue, Helmut Jonuleit

Int J Mol Sci· January 2021

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Using immuno-PET imaging to monitor kinetics of T cell-mediated inflammation and treatment efficiency in a humanized mouse model for GvHD.
Stefanie Pektor, Janine Schlöder, Benedikt Klasen, Nicole Bausbacher, Daniel-Christoph Wagner, Helmut Jonuleit

Eur J Nucl Med Mol Imaging· May 2020

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RAF kinases are stabilized and required for dendritic cell differentiation and function.
Kristina Riegel, Janine Schlöder, Marco Sobczak, Helmut Jonuleit, Bernd Thiede

Cell Death Differ· April 2020

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Humanized mice in cutaneous leishmaniasis-Suitability analysis of human PBMC transfer into immunodeficient mice.
Michael R Fischer, Anja I Schermann, Trix Twelkmeyer, Beate Lorenz, Joanna Wegner, Helmut Jonuleit

Exp Dermatol· September 2019

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TCR signalling network organization at the immunological synapses of murine regulatory T cells.
Marco van Ham, René Teich, Lars Philipsen, Jana Niemz, Nicole Amsberg, Helmut Jonuleit

Eur J Immunol· December 2017

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Novel Concept of CD4-Mediated Activation of Regulatory T Cells for the Treatment of Graft-Versus-Host Disease.
Janine Schlöder, Carsten Berges, Andrea Tuettenberg, Helmut Jonuleit

Front Immunol· November 2017

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Immunization with a Synthetic Human MUC1 Glycopeptide Vaccine against Tumor-Associated MUC1 Breaks Tolerance in Human MUC1 Transgenic Mice.
Natascha Stergiou, Markus Glaffig, Helmut Jonuleit, Edgar Schmitt, Horst Kunz

ChemMedChem· September 2017

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Dendritic Mesoporous Silica Nanoparticles for pH-Stimuli-Responsive Drug Delivery of TNF-Alpha.
Arne Kienzle, Sven Kurch, Janine Schlöder, Carsten Berges, Robert Ose, Helmut Jonuleit

Adv Healthc Mater· July 2017

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Bioconjugation of Small Molecules to RNA Impedes Its Recognition by Toll-Like Receptor 7.
Isabell Hellmuth, Isabel Freund, Janine Schlöder, Salifu Seidu-Larry, Kathrin Thüring, Helmut Jonuleit

Front Immunol· March 2017

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Dimethyl Fumarate Therapy Significantly Improves the Responsiveness of T Cells in Multiple Sclerosis Patients for Immunoregulation by Regulatory T Cells.
Janine Schlöder, Carsten Berges, Felix Luessi, Helmut Jonuleit

Int J Mol Sci· January 2017

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Treg cells as potential cellular targets for functionalized nanoparticles in cancer therapy.
Helmut Jonuleit, Tobias Bopp, Christian Becker

Nanomedicine (Lond)· October 2016

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Pillars Article: Induction of Tolerance by IL-10-Treated Dendritic Cells. J. Immunol. 1997. 159: 4772-4780.
Kerstin Steinbrink, Matthias Wölfl, Helmut Jonuleit, Jürgen Knop, Alexander H Enk

J Immunol· September 2016

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Kinome Profiling of Regulatory T Cells: A Closer Look into a Complex Intracellular Network.
Andrea Tuettenberg, Susanne A Hahn, Johanna Mazur, Aslihan Gerhold-Ay, Jetse Scholma, Helmut Jonuleit

PLoS One· July 2016

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A key role of GARP in the immune suppressive tumor microenvironment.
Susanne A Hahn, Annemarie Neuhoff, Jenny Landsberg, Jonathan Schupp, Daniela Eberts, Helmut Jonuleit

Oncotarget· July 2016

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Editorial: Current Concepts of Cellular and Biological Drugs to Modulate Regulatory T Cell Activity in the Clinic.
Helmut Jonuleit, Tobias Bopp

Front Immunol· May 2016

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FTY720 (fingolimod) treatment tips the balance towards less immunogenic antigen-presenting cells in patients with multiple sclerosis.
Felix Luessi, Stefan Kraus, Bettina Trinschek, Steffen Lerch, Robert Ploen, Helmut Jonuleit

Mult Scler· December 2015

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Interferon-Beta Therapy of Multiple Sclerosis Patients Improves the Responsiveness of T Cells for Immune Suppression by Regulatory T Cells.
Bettina Trinschek, Felix Luessi, Catharina C Gross, Heinz Wiendl, Helmut Jonuleit

Int J Mol Sci· July 2015

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A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway.
Bianca Helling, Martin König, Benjamin Dälken, Andre Engling, Wolfgang Krömer, Helmut Jonuleit

Immunol Cell Biol· April 2015

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Protein kinase CK2 enables regulatory T cells to suppress excessive TH2 responses in vivo.
Alexander Ulges, Matthias Klein, Sebastian Reuter, Bastian Gerlitzki, Markus Hoffmann, Helmut Jonuleit

Nat Immunol· March 2015

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IgG1 anti-epidermal growth factor receptor antibodies induce CD8-dependent antitumor activity.
Jan Kubach, Mario Hubo, Christiane Amendt, Christopher Stroh, Helmut Jonuleit

Int J Cancer· February 2015

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