Publications by authors named "Hengjing Cui"

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Novel PREP ligand, HUP-46, ameliorates behavioral deficits in an alpha-synuclein based Parkinson's disease model.
Tommi Kilpeläinen, Rui Yang, Jyri Toivio, Tony Eteläinen, Francesca De Lorenzo, Hengjing Cui

Exp Neurol· December 2025

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5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein-Protein Interaction-Derived Functions.
Henri T Pätsi, Tommi P Kilpeläinen, Mikael Jumppanen, Johanna Uhari-Väänänen, Pieter Van Wielendaele, Hengjing Cui

J Med Chem· April 2024

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Nigrostriatal 6-hydroxydopamine lesions increase alpha-synuclein levels and permeability in rat colon.
Hengjing Cui, Joshua D Elford, Okko Alitalo, Paula Perez-Pardo, Janne Tampio

Neurobiol Aging· September 2023

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Nonpeptidic Oxazole-Based Prolyl Oligopeptidase Ligands with Disease-Modifying Effects on α-Synuclein Mouse Models of Parkinson's Disease.
Tommi P Kilpeläinen, Henri T Pätsi, Reinis Svarcbahs, Ulrika H Julku, Tony S Eteläinen, Hengjing Cui

J Med Chem· June 2023

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A prolyl oligopeptidase inhibitor reduces tau pathology in cellular models and in mice with tauopathy.
Tony S Eteläinen, M Catarina Silva, Johanna K Uhari-Väänänen, Francesca De Lorenzo, Maria H Jäntti, Hengjing Cui

Sci Transl Med· April 2023

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Deletion or inhibition of prolyl oligopeptidase blocks lithium-induced phosphorylation of GSK3b and Akt by activation of protein phosphatase 2A.
Timo T Myöhänen, Freke Mertens, Susanna Norrbacka, Hengjing Cui

Basic Clin Pharmacol Toxicol· October 2021

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Prolyl oligopeptidase inhibition reduces alpha-synuclein aggregation in a cellular model of multiple system atrophy.
Hengjing Cui, Tommi Kilpeläinen, Lydia Zouzoula, Samuli Auno, Kalevi Trontti

J Cell Mol Med· October 2021

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Corrigendum to "Prolyl oligopeptidase inhibition by KYP-2407 increases alpha-synuclein fibril degradation in neuron-like cells" [Biomed. Pharmacother. 131 (2020) 110788].
Jinar Rostami, Maria Jäntti, Hengjing Cui, Maiju K Rinne, Jyrki P Kukkonen

Biomed Pharmacother· January 2021

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Prolyl oligopeptidase inhibition by KYP-2407 increases alpha-synuclein fibril degradation in neuron-like cells.
Jinar Rostami, Maria Jäntti, Hengjing Cui, Maiju K Rinne, Jyrki P Kukkonen

Biomed Pharmacother· November 2020

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N-stearoyltyrosine protects primary cortical neurons against oxygen-glucose deprivation-induced apoptosis through inhibiting anandamide inactivation system.
Heng-Jing Cui, Sha Liu, Rui Yang, Guo-Hui Fu, Yang Lu

Neurosci Res· October 2017

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Dipotassium N-stearoyltyrosinate ameliorated pathological injuries in triple-transgenic mouse model of Alzheimer's disease.
Sha Liu, Shuang-Qi Tang, Heng-Jing Cui, Sha Yin, Ming Yin

J Pharmacol Sci· September 2016

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N-Stearoyltyrosine protects primary cortical neurons against Aβ(1-40)-induced injury through inhibiting endocannabinoid degradation.
Hengjing Cui, Rui Yang, Sha Liu, Guohui Fu, Yang Lu

Life Sci· March 2015

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N-stearoyltyrosine protects against glutamate-induced oxidative toxicity by an apoptosis-inducing factor (AIF)-mediated caspase-independent cell death pathway.
Rui Yang, Heng-Jing Cui, Hua Wang, Yan Wang, Jian-Hua Liu

J Pharmacol Sci· October 2014

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Gastrin inhibits a novel, pathological colon cancer signaling pathway involving EGR1, AE2, and P-ERK.
Ling-Jun Song, Rui-Jun Liu, Zhi Zeng, Seth L Alper, Heng-Jing Cui

J Mol Med (Berl)· June 2012

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