Publications by authors named "Henner Farin"

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Synergistic targeting of cancer cells through simultaneous inhibition of key metabolic enzymes.
Jan Dreute, Julia Stengel, Jonas Becher, David van den Borre, Maximilian Pfisterer, Henner F Farin

Cell Death Differ· December 2025

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Establishment of Patient-Derived Organoids from Colorectal Cancer Resection Samples.
Didem Seven, Szilvia Baron, Henner F Farin

Methods Mol Biol· July 2025

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Head and neck tumor organoid biobank for modelling individual responses to radiation therapy according to the TP53/HPV status.
Christian Issing, Constantin Menche, Mara Romero Richter, Mohammed H Mosa, Jens von der Grün, Henner F Farin

J Exp Clin Cancer Res· March 2025

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Toward target 2035: EUbOPEN - a public-private partnership to enable & unlock biology in the open.
Claudia Tredup, Suzanne Ackloo, Hartmut Beck, Peter J Brown, Alex N Bullock, Henner F Farin

RSC Med Chem· February 2025

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Author Correction: Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways.
Naziia Kurmasheva, Aida Said, Boaz Wong, Priscilla Kinderman, Xiaoying Han, Henner F Farin

Nat Commun· December 2024

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ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer.
Constantin Menche, Harald Schuhwerk, Isabell Armstark, Pooja Gupta, Kathrin Fuchs, Henner F Farin

EMBO Rep· August 2024

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Downregulation of V-ATPase V Sector Induces Microvillus Atrophy Independently of Apical Trafficking in the Mammalian Intestine.
Aurélien Bidaud-Meynard, Anne Bourdais, Ophélie Nicolle, Maela Duclos, Jad Saleh, Henner F Farin

Cell Mol Gastroenterol Hepatol· May 2024

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Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways.
Naziia Kurmasheva, Aida Said, Boaz Wong, Priscilla Kinderman, Xiaoying Han, Henner F Farin

Nat Commun· May 2024

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Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer.
Christina Plattner, Giorgia Lamberti, Peter Blattmann, Alexander Kirchmair, Dietmar Rieder, Henner F Farin

iScience· December 2023

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Actin dynamics regulation by TTC7A/PI4KIIIα limits DNA damage and cell death under confinement.
Tania Gajardo, Mathilde Bernard, Marie Lô, Elisa Turck, Claire Leveau, Henner F Farin

J Allergy Clin Immunol· October 2023

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Colorectal Cancer Organoid-Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses.
Henner F Farin, Mohammed H Mosa, Benardina Ndreshkjana, Britta M Grebbin, Birgit Ritter

Cancer Discov· October 2023

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Immune escape of colorectal tumours via local LRH-1/Cyp11b1-mediated synthesis of immunosuppressive glucocorticoids.
Asma Ahmed, Cindy Reinhold, Eileen Breunig, Truong San Phan, Lea Dietrich, Henner F Farin

Mol Oncol· August 2023

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Deep Annotation of Donated Chemical Probes (DCP) in Organotypic Human Liver Cultures and Patient-Derived Organoids from Tumor and Normal Colorectum.
Claudia Tredup, Benardina Ndreshkjana, Natalie S Schneider, Amelie Tjaden, Aurino M Kemas, Henner F Farin

ACS Chem Biol· April 2023

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Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy.
Larsen Vornholz, Sophie E Isay, Zsuzsanna Kurgyis, Daniel C Strobl, Patricia Loll, Henner F Farin

Sci Adv· March 2023

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Loss of SUV420H2-Dependent Chromatin Compaction Drives Right-Sided Colon Cancer Progression.
Verawan Boonsanay, Mohammed H Mosa, Mario Looso, Dieter Weichenhan, Fatih Ceteci, Henner F Farin

Gastroenterology· February 2023

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Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy.
Dominic Denk, Valentina Petrocelli, Claire Conche, Moritz Drachsler, Paul K Ziegler, Henner F Farin

Immunity· November 2022

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Strategies for genetic manipulation of adult stem cell-derived organoids.
Constantin Menche, Henner F Farin

Exp Mol Med· October 2021

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A Wnt-Induced Phenotypic Switch in Cancer-Associated Fibroblasts Inhibits EMT in Colorectal Cancer.
Mohammed H Mosa, Birgitta E Michels, Constantin Menche, Adele M Nicolas, Tahmineh Darvishi, Henner F Farin

Cancer Res· December 2020

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AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer.
Julia Varga, Adele Nicolas, Valentina Petrocelli, Marina Pesic, Abdelrahman Mahmoud, Henner F Farin

J Exp Med· October 2020

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STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis.
Christina Heichler, Kristina Scheibe, Anabel Schmied, Carol I Geppert, Benjamin Schmid, Henner F Farin

Gut· July 2020

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Cellular and Molecular Changes of Brain Metastases-Associated Myeloid Cells during Disease Progression and Therapeutic Response.
Michael Schulz, Birgitta Michels, Katja Niesel, Stefan Stein, Henner Farin

iScience· June 2020

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Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids.
Birgitta E Michels, Mohammed H Mosa, Barbara I Streibl, Tianzuo Zhan, Constantin Menche, Henner F Farin

Cell Stem Cell· May 2020

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Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids.
Svenja Wiechmann, Pierre Maisonneuve, Britta M Grebbin, Meike Hoffmeister, Manuel Kaulich, Henner F Farin

J Biol Chem· April 2020

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Cancer-induced inflammation and inflammation-induced cancer in colon: a role for S1P lyase.
Anja Schwiebs, Martina Herrero San Juan, Katrin G Schmidt, Eliza Wiercinska, Martin Anlauf, Henner F Farin

Oncogene· June 2019

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3D model for CAR-mediated cytotoxicity using patient-derived colorectal cancer organoids.
Theresa E Schnalzger, Marnix Hp de Groot, Congcong Zhang, Mohammed H Mosa, Birgitta E Michels, Henner F Farin

EMBO J· June 2019

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