Publications by authors named "Henrik Graden"

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Discovery of AZD4144, a Selective and Potent NLRP3 Inhibitor for the Treatment of Inflammatory Diseases.
Anders Johansson, Hiroshi Sugama, Niklas Larsson, Susanne Winiwarter, Kosuke Yoshida

J Med Chem· July 2025

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Discovery of Clinical Candidate AZD5462, a Selective Oral Allosteric RXFP1 Agonist for Treatment of Heart Failure.
Kenneth L Granberg, Shigeki Sakamaki, Niklas Larsson, Fredrik Bergström, Ryuichi Fuchigami

J Med Chem· March 2024

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Identification of novel GPR81 agonist lead series for target biology evaluation.
Öjvind Davidsson, Kristina Nilsson, Jonas Brånalt, Terese Andersson, Kristina Berggren

Bioorg Med Chem Lett· February 2020

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Lighting Up DNA with the Environment-Sensitive Bright Adenine Analogue qAN4.
Anders F Füchtbauer, Moa S Wranne, Sangamesh Sarangamath, Mattias Bood, Afaf H El-Sagheer

Chempluschem· February 2020

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Synthesis, oligonucleotide incorporation and fluorescence properties in DNA of a bicyclic thymine analogue.
Christopher P Lawson, Anders F Füchtbauer, Moa S Wranne, Tristan Giraud, Thomas Floyd

Sci Rep· September 2018

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Toward Complete Sequence Flexibility of Nucleic Acid Base Analogue FRET.
Moa S Wranne, Anders Foller Füchtbauer, Blaise Dumat, Mattias Bood, Afaf H El-Sagheer

J Am Chem Soc· July 2017

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Development of bright fluorescent quadracyclic adenine analogues: TDDFT-calculation supported rational design.
Anders Foller Larsen, Blaise Dumat, Moa S Wranne, Christopher P Lawson, Søren Preus

Sci Rep· July 2015

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Second-generation fluorescent quadracyclic adenine analogues: environment-responsive probes with enhanced brightness.
Blaise Dumat, Mattias Bood, Moa S Wranne, Christopher P Lawson, Anders Foller Larsen

Chemistry· March 2015

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Synthesis and functionalization of cyclic sulfonimidamides: a novel chiral heterocyclic carboxylic Acid bioisostere.
Nils Pemberton, Henrik Graden, Emma Evertsson, Emma Bratt, Matti Lepistö

ACS Med Chem Lett· July 2012

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Optimization of 2-piperidin-4-yl-acetamides as melanin-concentrating hormone receptor 1 (MCH-R1) antagonists: Designing out hERG inhibition.
Susanne Berglund, Bryan J Egner, Henrik Gradén, Joakim Gradén, David G A Morgan

Bioorg Med Chem Lett· August 2009

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Optimization of piperidin-4-yl-urea-containing melanin-concentrating hormone receptor 1 (MCH-R1) antagonists: Reducing hERG-associated liabilities.
Susanne Berglund, Bryan J Egner, Henrik Gradén, Joakim Gradén, David G A Morgan

Bioorg Med Chem Lett· August 2009

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Synthetic applications of cationic iron and cobalt carbonyl complexes.
Karen M Bromfield, Henrik Gradén, Natalie Ljungdahl, Nina Kann

Dalton Trans· July 2009

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Discovery of 1,3-disubstituted-1H-pyrrole derivatives as potent melanin-concentrating hormone receptor 1 (MCH-R1) antagonists.
Susanne Berglund, Bryan J Egner, Henrik Gradén, Joakim Gradén, David G A Morgan

Bioorg Med Chem Lett· September 2008

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Carbohydrate functionalization using cationic iron carbonyl complexes.
Anders Bergh, Henrik Gradén, Núria Parera Pera, Thomas Olsson, Ulf J Nilsson

Carbohydr Res· July 2008

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An iron carbonyl approach to the influenza neuraminidase inhibitor oseltamivir.
Karen M Bromfield, Henrik Gradén, Daniel P Hagberg, Thomas Olsson, Nina Kann

Chem Commun (Camb)· August 2007

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Iron carbonyl-mediated parallel solution-phase synthesis of cyclohexadienoic acid amides.
Henrik Gradén, Jesper Hallberg, Nina Kann, Thomas Olsson

J Comb Chem· January 2006

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Carbon-carbon and carbon-heteroatom bond formation on solid phase using cationic iron carbonyl complexes.
Henrik Gradén, Thomas Olsson, Nina Kann

Org Lett· August 2005

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