Publications by authors named "Hester Bange"

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A Patient-Derived 3D Cyst Model of Polycystic Kidney Disease That Mimics Disease Development and Responds to Repurposing Candidates.
Alina Meyer, Bola Khalil, Margarita Iljin, Hester Bange, Leo S Price

Clin Transl Sci· April 2025

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Computational drug discovery approaches identify mebendazole as a candidate treatment for autosomal dominant polycystic kidney disease.
Philip W Brownjohn, Azedine Zoufir, Daniel J O'Donovan, Saatviga Sudhahar, Alexander Syme, Hester Bange

Front Pharmacol· May 2024

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A novel direct adenosine monophosphate kinase activator ameliorates disease progression in preclinical models of Autosomal Dominant Polycystic Kidney Disease.
Pascale Gluais Dagorn, Bjoern Buchholz, Andre Kraus, Battsetseg Batchuluun, Hester Bange

Kidney Int· May 2023

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In vitro 3D phenotypic drug screen identifies celastrol as an effective in vivo inhibitor of polycystic kidney disease.
Tijmen H Booij, Wouter N Leonhard, Hester Bange, Kuan Yan, Michiel Fokkelman

J Mol Cell Biol· August 2020

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Renal cyst growth is attenuated by a combination treatment of tolvaptan and pioglitazone, while pioglitazone treatment alone is not effective.
Anish A Kanhai, Hester Bange, Lotte Verburg, Kyra L Dijkstra, Leo S Price

Sci Rep· February 2020

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Prioritization of novel ADPKD drug candidates from disease-stage specific gene expression profiles.
Tareq B Malas, Wouter N Leonhard, Hester Bange, Zoraide Granchi, Kristina M Hettne

EBioMedicine· January 2020

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High-Throughput Phenotypic Screening of Kinase Inhibitors to Identify Drug Targets for Polycystic Kidney Disease.
Tijmen H Booij, Hester Bange, Wouter N Leonhard, Kuan Yan, Michiel Fokkelman

SLAS Discov· September 2017

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