Publications by authors named "Hideya Hayashi"

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Successful shrinkage of a recurrent partially thrombosed symptomatic large basilar tip aneurysm using a Target 3D Coil.
Noriaki Ashida, Atsushi Fujita, Hideya Hayashi, Masashi Higashino, Yusuke Ikeuchi

Surg Neurol Int· March 2024

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Acute Occlusion of the Ventriculoperitoneal Shunt Due to Factor XIII Deficiency-related Postoperative Hemorrhage: A Case Report.
Shunsuke Yamanishi, Hidehito Kimura, Hideya Hayashi, Yoji Yamaguchi, Yuichi Fujita

NMC Case Rep J· August 2021

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Structure-activity relationships of novel HIV-1 protease inhibitors containing the 3-amino-2-chlorobenzoyl-allophenylnorstatine structure.
Tsutomu Mimoto, Satoshi Nojima, Keisuke Terashima, Haruo Takaku, Makoto Shintani, Hideya Hayashi

Bioorg Med Chem· February 2008

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Structure-activity and structure-metabolism relationships of HIV protease inhibitors containing the 3-hydroxy-2-methylbenzoyl-allophenylnorstatine structure.
Tsutomu Mimoto, Keisuke Terashima, Satoshi Nojima, Haruo Takaku, Mitsunobu Nakayama, Hideya Hayashi

Bioorg Med Chem· January 2004

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Structure and activity relationships of novel uracil derivatives as topical anti-inflammatory agents.
Yoshiaki Isobe, Masanori Tobe, Yoshifumi Inoue, Masakazu Isobe, Masami Tsuchiya, Hideya Hayashi

Bioorg Med Chem· November 2003

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A novel structural class of potent inhibitors of NF-kappa B activation: structure-activity relationships and biological effects of 6-aminoquinazoline derivatives.
Masanori Tobe, Yoshiaki Isobe, Hideyuki Tomizawa, Takahiro Nagasaki, Hirotada Takahashi, Hideya Hayashi

Bioorg Med Chem· September 2003

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Synthesis and evaluation of 6-nitro-7-(1-piperazino)quinazolines: dual-acting compounds with inhibitory activities toward both tumor necrosis factor-alpha (TNF-alpha) production and T cell proliferation.
Masanori Tobe, Yoshiaki Isobe, Hideyuki Tomizawa, Takahiro Nagasaki, Masamitsu Aoki, Hideya Hayashi

Chem Pharm Bull (Tokyo)· September 2003

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On-column refolding and characterization of soluble human interleukin-15 receptor alpha-chain produced in Escherichia coli.
Mitsuhiro Matsumoto, Satoru Misawa, Kouhei Tsumoto, Izumi Kumagai, Hideya Hayashi

Protein Expr Purif· September 2003

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Synthesis and structure-activity relationships of 2-substituted-8-hydroxyadenine derivatives as orally available interferon inducers without emetic side effects.
Yoshiaki Isobe, Masanori Tobe, Haruhisa Ogita, Ayumu Kurimoto, Tetsuhiro Ogino, Hideya Hayashi

Bioorg Med Chem· August 2003

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Inhibitory activity of CX-659S, a novel diaminouracil derivative, against the rebound phenomenon following withdrawal of corticosteroid therapy for chronic contact hypersensitivity responses.
Yoshifumi Inoue, Masakazu Isobe, Tetsuo Shiohara, Hideya Hayashi

Int Arch Allergy Immunol· June 2003

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Finding of an isoleucine derivative of a recombinant protein for pharmaceutical use.
Ryo Muramatsu, Satoru Misawa, Hideya Hayashi

J Pharm Biomed Anal· April 2003

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Inhibitory activities of novel pyrimidine derivatives on the contact hypersensitivity reaction.
Yoshiaki Isobe, Masanori Tobe, Yoshifumi Inoue, Yuso Goto, Fumihiro Obara, Hideya Hayashi

Chem Pharm Bull (Tokyo)· March 2003

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Discovery of quinazolines as a novel structural class of potent inhibitors of NF-kappa B activation.
Masanori Tobe, Yoshiaki Isobe, Hideyuki Tomizawa, Takahiro Nagasaki, Hirotada Takahashi, Hideya Hayashi

Bioorg Med Chem· February 2003

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Structure-activity relationships of 6-fluoroquinazolines: dual-acting compounds with inhibitory activities toward both TNF-alpha production and T cell proliferation.
Masanori Tobe, Yoshiaki Isobe, Hideyuki Tomizawa, Takahiro Nagasaki, Fumihiro Obara, Hideya Hayashi

Bioorg Med Chem· February 2003

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Synthesis of potent and selective inhibitors against the proliferation of human coronary artery smooth muscle cells.
Haruhisa Ogita, Yoshiaki Isobe, Haruo Takaku, Rena Sekine, Yuso Goto, Hideya Hayashi

Chem Pharm Bull (Tokyo)· February 2003

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The combined effect of topical CX-659S, a novel diaminouracil derivative, with topical corticosteroid on the three types of allergic responses in mice or guinea pigs.
Yoshifumi Inoue, Masakazu Isobe, Hideya Hayashi

J Pharmacol Sci· January 2003

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Synthesis and structure-activity relationship of diarylamide derivatives as selective inhibitors of the proliferation of human endothelial cells.
Haruhisa Ogita, Yoshiaki Isobe, Haruo Takaku, Rena Sekine, Yuso Goto, Hideya Hayashi

Bioorg Med Chem· November 2002

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Inhibition of telomerase by linear-chain fatty acids: a structural analysis.
Masako Oda, Takamasa Ueno, Nobuyuki Kasai, Hirotada Takahashi, Hiromi Yoshida, Hideya Hayashi

Biochem J· October 2002

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Synthesis and activity of a metabolite of (S)-6-amino-5-(6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamido)-3-methyl-1-phenyl-2,4-(1H,3H)-pyrimidinedione (CX-659S).
Yoshiaki Isobe, Masanori Tobe, Osamu Takahashi, Yuso Goto, Yoshifumi Inoue, Hideya Hayashi

Chem Pharm Bull (Tokyo)· October 2002

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Inhibition of hepatitis C virus NS3 protease by peptides derived from complementarity-determining regions (CDRs) of the monoclonal antibody 8D4: tolerance of a CDR peptide to conformational changes of a target.
Kouhei Tsumoto, Satoru Misawa, Yoichi Ohba, Takamasa Ueno, Hideya Hayashi

FEBS Lett· August 2002

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Structure-activity relationships of 6-nitroquinazolines: dual-acting compounds with inhibitory activities toward both TNF-alpha production and T cell proliferation.
Masanori Tobe, Yoshiaki Isobe, Hideyuki Tomizawa, Takahiro Nagasaki, Fumihiro Obara, Hideya Hayashi

Chem Pharm Bull (Tokyo)· August 2002

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Synthesis and structure-activity relationship of diarylamide urea derivatives as selective inhibitors of the proliferation of human coronary artery smooth muscle cells.
Haruhisa Ogita, Yoshiaki Isobe, Haruo Takaku, Rena Sekine, Yuso Goto, Hideya Hayashi

Bioorg Med Chem· June 2002

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CX-659S: a novel diaminouracil derivative that has antioxidative and acute anti-inflammatory activities.
Yuso Goto, Nobuo Watanabe, Noriaki Kogawa, Masami Tsuchiya, Osamu Takahashi, Hideya Hayashi

Eur J Pharmacol· March 2002

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Existence of beta-methylnorleucine in recombinant hirudin produced by Escherichia coli.
Ryo Muramatsu, Toru Negishi, Tsutomu Mimoto, Akira Miura, Satoru Misawa, Hideya Hayashi

J Biotechnol· February 2002

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