Publications by authors named "Hitesh B Mistry"

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A Pharmacokinetic and Pharmacodynamic Model of an IL-12 Anchored-Drug Conjugate for the Treatment of Solid Tumors.
Hitesh B Mistry, David Hodson, Sailaja Battula, Michael M Schmidt, Robert Tighe

Mol Cancer Ther· July 2025

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Explaining in-vitro to in-vivo efficacy correlations in oncology pre-clinical development via a semi-mechanistic mathematical model.
Heinrich J Huber, Hitesh B Mistry

J Pharmacokinet Pharmacodyn· April 2024

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Skipping a pillar does not make for strong foundations: Pharmacokinetic-pharmacodynamic reasoning behind the shape of dose-response relationships in oncology.
James W T Yates, Hitesh B Mistry

CPT Pharmacometrics Syst Pharmacol· November 2023

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Radius additivity score: a novel combination index for tumour growth inhibition in fixed-dose xenograft studies.
Nicola Melillo, Jake Dickinson, Lu Tan, Hitesh B Mistry, Heinrich J Huber

Front Pharmacol· October 2023

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Association between radiotherapy protocol variations and outcome in the CONVERT trial.
Romaana Mir, Nicki Groom, Hitesh B Mistry, Elena Wilson, Corinne Faivre-Finn

Clin Transl Radiat Oncol· March 2023

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Determining bioequivalence possibilities of long acting injectables through population PK modelling.
Parmesh Gajjar, Jake Dickinson, Harri Dickinson, Linette Ruston, Hitesh B Mistry

Eur J Pharm Sci· December 2022

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Pretreatment Lymphocyte Count Predicts Benefit From Concurrent Chemotherapy With Radiotherapy in Oropharyngeal Cancer.
James M Price, Hitesh B Mistry, Guy Betts, Eleanor J Cheadle, Lynne Dixon

J Clin Oncol· July 2022

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Simulating RTOG 0617 using Genomic Adjusted Radiation Dose: Comparing Apples With Oranges.
Hitesh B Mistry

J Thorac Oncol· May 2021

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On the reporting and analysis of a cancer evolutionary adaptive dosing trial.
Hitesh B Mistry

Nat Commun· January 2021

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Exploring a model-based analysis of patient derived xenograft studies in oncology drug development.
Jake Dickinson, Marcel de Matas, Paul A Dickinson, Hitesh B Mistry

PeerJ· January 2021

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Diffusion model comparison identifies distinct tumor sub-regions and tracks treatment response.
Damien J McHugh, Grazyna Lipowska-Bhalla, Muhammad Babur, Yvonne Watson, Isabel Peset, Hitesh B Mistry

Magn Reson Med· September 2020

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The spindle assembly checkpoint and speciation.
Robert C Jackson, Hitesh B Mistry

PeerJ· May 2020

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Small Models for Big Data.
Hitesh B Mistry, David Orrell

Clin Pharmacol Ther· April 2020

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Quantifying Preexisting Resistant and Persister Populations-Letter.
Hitesh B Mistry, James W T Yates

Cancer Res· October 2019

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Resistance models to EGFR inhibition and chemotherapy in non-small cell lung cancer via analysis of tumour size dynamics.
Hitesh B Mistry, Gabriel Helmlinger, Nidal Al-Huniti, Karthick Vishwanathan, James Yates

Cancer Chemother Pharmacol· July 2019

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Comprehensive In Vitro Proarrhythmic Assay Complexity Bias.
Hitesh B Mistry

Clin Pharmacol Ther· June 2019

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A simple model of a growing tumour.
David Orrell, Hitesh B Mistry

PeerJ· May 2019

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QSP Versus the Rest: Let the Competition Commence!
Hitesh B Mistry

CPT Pharmacometrics Syst Pharmacol· August 2018

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Model based analysis of the heterogeneity in the tumour size dynamics differentiates vemurafenib, dabrafenib and trametinib in metastatic melanoma.
Hitesh B Mistry, David Orrell, Raluca Eftimie

Cancer Chemother Pharmacol· February 2018

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Complex versus simple models: ion-channel cardiac toxicity prediction.
Hitesh B Mistry

PeerJ· February 2018

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On the relationship between tumour growth rate and survival in non-small cell lung cancer.
Hitesh B Mistry

PeerJ· November 2017

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To the Editor- Misuse of null hypothesis testing: Analysis of biophysical model simulations.
Hitesh B Mistry

Heart Rhythm· April 2017

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Optimizing Clinical Drug Product Performance: Applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid.
Paul A Dickinson, Filippos Kesisoglou, Talia Flanagan, Marilyn N Martinez, Hitesh B Mistry

J Pharm Sci· November 2016

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A new classifier-based strategy for in-silico ion-channel cardiac drug safety assessment.
Hitesh B Mistry, Mark R Davies, Giovanni Y Di Veroli

Front Pharmacol· April 2015

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The biopharmaceutics risk assessment roadmap for optimizing clinical drug product performance.
Arzu Selen, Paul A Dickinson, Anette Müllertz, John R Crison, Hitesh B Mistry

J Pharm Sci· November 2014

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