Publications by authors named "Hitomi Tsuchida"

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GPR75 signaling is dispensable for reproduction but contributes to feeding and body growth in rats on normal chow and is involved in high-fat diet-induced hyperphagia, obesity, and hyperglycemia development.
Yuki Otsuka, Naoko Inoue, Safiullah Hazim, Shunsuke Seki, Hitomi Tsuchida

Endocr J· December 2025

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Involvement of nuclear receptor corepressor 2 (NCOR2) in estrogen-induced repression of arcuate Kiss1 expression in female rats.
Marina Takizawa, Sae Miyazaki, Hitomi Tsuchida, Mayuko Nagae, Shunsuke Seki

J Reprod Dev· April 2025

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AVPV neuron-specific knockdown of purinergic P2X2 receptor suppresses LH surge and ovulation in rats.
Safiullah Hazim, Shunsuke Seki, Ryoya Yabushita, Mayuko Nagae, Hitomi Tsuchida

J Reprod Dev· December 2024

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Central δ/κ opioid receptor signaling pathways mediate chronic and/or acute suckling-induced LH suppression in rats during late lactation.
Yoshihisa Uenoyama, Miku Nonogaki, Hitomi Tsuchida, Marina Takizawa, Sena Matsuzaki

J Reprod Dev· October 2024

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Type 2 Myocardial Infarction Caused by Orthostatic Hypotension With Post-transcatheter Aortic Valve Implantation: A Case Report.
Hitomi Tsuchida, Shiho Amano, Chiaki Sano, Ryuichi Ohta

Cureus· February 2024

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Conditional Oprk1-dependent Kiss1 deletion in kisspeptin neurons caused estrogen-dependent LH pulse disruption and LH surge attenuation in female rats.
Mayuko Nagae, Koki Yamada, Yuki Enomoto, Mari Kometani, Hitomi Tsuchida

Sci Rep· November 2023

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Sex difference in developmental changes in visualized Kiss1 neurons in newly generated Kiss1-Cre rats.
Koki Yamada, Mayuko Nagae, Tetsuya Mano, Hitomi Tsuchida, Safiullah Hazim

J Reprod Dev· October 2023

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Enkephalin-δ opioid receptor signaling partly mediates suppression of LH release during early lactation in rats.
Hitomi Tsuchida, Marina Takizawa, Miku Nonogaki, Naoko Inoue, Yoshihisa Uenoyama

J Reprod Dev· August 2023

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Hindbrain Adenosine 5-Triphosphate (ATP)-Purinergic Signaling Triggers LH Surge and Ovulation via Activation of AVPV Kisspeptin Neurons in Rats.
Naoko Inoue, Safiullah Hazim, Hitomi Tsuchida, Yuri Dohi, Ren Ishigaki

J Neurosci· March 2023

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Enkephalin-δ Opioid Receptor Signaling Mediates Glucoprivic Suppression of LH Pulse and Gluconeogenesis in Female Rats.
Hitomi Tsuchida, Miku Nonogaki, Marina Takizawa, Naoko Inoue, Yoshihisa Uenoyama

Endocrinology· January 2023

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Intronic Enhancer Is Essential for Expression in the Pituitary Gonadotrope and for Postnatal Development of Male Reproductive Organs in a Mouse Model.
Yuichi Shima, Kanako Miyabayashi, Takami Mori, Koji Ono, Mizuki Kajimoto, Hitomi Tsuchida

Int J Mol Sci· December 2022

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Dynorphin-κ-opioid receptor signaling, but not µ-opioid receptor signaling, partly mediates the suppression of luteinizing hormone release during late lactation in rats.
Hitomi Tsuchida, Miku Nonogaki, Naoko Inoue, Yoshihisa Uenoyama, Hiroko Tsukamura

Neurosci Lett· November 2022

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Opioidergic pathways and kisspeptin in the regulation of female reproduction in mammals.
Yoshihisa Uenoyama, Hitomi Tsuchida, Mayuko Nagae, Naoko Inoue, Hiroko Tsukamura

Front Neurosci· August 2022

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Central somatostatin-somatostatin receptor 2 signaling mediates lactational suppression of luteinizing hormone release via the inhibition of glutamatergic interneurons during late lactation in rats.
Arisa Sugimoto, Hitomi Tsuchida, Mayuko Nagae, Naoko Inoue, Yoshihisa Uenoyama

J Reprod Dev· June 2022

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Role of KNDy Neurons Expressing Kisspeptin, Neurokinin B, and Dynorphin A as a GnRH Pulse Generator Controlling Mammalian Reproduction.
Yoshihisa Uenoyama, Mayuko Nagae, Hitomi Tsuchida, Naoko Inoue, Hiroko Tsukamura

Front Endocrinol (Lausanne)· February 2022

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Metformin action in the gut-insight provided by [F]FDG PET imaging.
Hitomi Tsuchida, Yasuko Morita, Munenobu Nogami, Wataru Ogawa

Diabetol Int· January 2022

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Central µ-Opioid Receptor Antagonism Blocks Glucoprivic LH Pulse Suppression and Gluconeogenesis/Feeding in Female Rats.
Hitomi Tsuchida, Narumi Kawai, Koki Yamada, Marina Takizawa, Naoko Inoue

Endocrinology· October 2021

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Effect of diet-induced obesity on kisspeptin-neurokinin B-dynorphin A neurons in the arcuate nucleus and luteinizing hormone secretion in sex hormone-primed male and female rats.
Shiori Minabe, Kinuyo Iwata, Hitomi Tsuchida, Hiroko Tsukamura, Hitoshi Ozawa

Peptides· August 2021

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Direct evidence that KNDy neurons maintain gonadotropin pulses and folliculogenesis as the GnRH pulse generator.
Mayuko Nagae, Yoshihisa Uenoyama, Saki Okamoto, Hitomi Tsuchida, Kana Ikegami

Proc Natl Acad Sci U S A· February 2021

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Upregulation of S100A10 in metastasized breast cancer stem cells.
Hisano Yanagi, Takashi Watanabe, Tatsunori Nishimura, Takanori Hayashi, Seishi Kono, Hitomi Tsuchida

Cancer Sci· December 2020

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Paraventricular Dynorphin A Neurons Mediate LH Pulse Suppression Induced by Hindbrain Glucoprivation in Female Rats.
Hitomi Tsuchida, Parvin Mostari, Koki Yamada, Sae Miyazaki, Yuki Enomoto

Endocrinology· November 2020

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Somatostatin-Somatostatin Receptor 2 Signaling Mediates LH Pulse Suppression in Lactating Rats.
Arisa Sugimoto, Hitomi Tsuchida, Nahoko Ieda, Kana Ikegami, Naoko Inoue

Endocrinology· February 2019

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