Publications by authors named "Mayuko Nagae"

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GPR75 signaling is dispensable for reproduction but contributes to feeding and body growth in rats on normal chow and is involved in high-fat diet-induced hyperphagia, obesity, and hyperglycemia development.
Yuki Otsuka, Naoko Inoue, Safiullah Hazim, Shunsuke Seki, Hitomi Tsuchida, Mayuko Nagae

Endocr J· December 2025

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Nociceptin-Opioid-Related Nociceptin Receptor 1 Signaling Partly Mediates Glucoprivic Suppression of Luteinizing Hormone Pulses in Female Rats: Arcuate Kiss1 Neurons as a Possible Target for Nociceptin.
Marina Takizawa, Koki Yamada, Mayuko Nagae, Shunsuke Seki, Sena Matsuzaki

Neuroendocrinology· September 2025

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Kisspeptin-dependent puberty onset triggered by increased Kiss1 and Pdyn expression in arcuate Tac3 neurons under reduced estrogen negative feedback and sufficient energy balance in female rats.
Mayuko Nagae, Sutisa Majarune, Takuma Kobayashi, Pelden Nima, Kei Horihata

Neuroendocrinology· September 2025

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Involvement of nuclear receptor corepressor 2 (NCOR2) in estrogen-induced repression of arcuate Kiss1 expression in female rats.
Marina Takizawa, Sae Miyazaki, Hitomi Tsuchida, Mayuko Nagae, Shunsuke Seki

J Reprod Dev· April 2025

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AVPV neuron-specific knockdown of purinergic P2X2 receptor suppresses LH surge and ovulation in rats.
Safiullah Hazim, Shunsuke Seki, Ryoya Yabushita, Mayuko Nagae, Hitomi Tsuchida

J Reprod Dev· December 2024

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Conditional Oprk1-dependent Kiss1 deletion in kisspeptin neurons caused estrogen-dependent LH pulse disruption and LH surge attenuation in female rats.
Mayuko Nagae, Koki Yamada, Yuki Enomoto, Mari Kometani, Hitomi Tsuchida

Sci Rep· November 2023

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Sex difference in developmental changes in visualized Kiss1 neurons in newly generated Kiss1-Cre rats.
Koki Yamada, Mayuko Nagae, Tetsuya Mano, Hitomi Tsuchida, Safiullah Hazim

J Reprod Dev· October 2023

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Opioidergic pathways and kisspeptin in the regulation of female reproduction in mammals.
Yoshihisa Uenoyama, Hitomi Tsuchida, Mayuko Nagae, Naoko Inoue, Hiroko Tsukamura

Front Neurosci· August 2022

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Central somatostatin-somatostatin receptor 2 signaling mediates lactational suppression of luteinizing hormone release via the inhibition of glutamatergic interneurons during late lactation in rats.
Arisa Sugimoto, Hitomi Tsuchida, Mayuko Nagae, Naoko Inoue, Yoshihisa Uenoyama

J Reprod Dev· June 2022

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Generation of Tfap2c-T2A-tdTomato knock-in reporter rats via adeno-associated virus-mediated efficient gene targeting.
Mami Oikawa, Mayuko Nagae, Naoaki Mizuno, Kenyu Iwatsuki, Fumika Yoshida

Mol Reprod Dev· March 2022

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Role of KNDy Neurons Expressing Kisspeptin, Neurokinin B, and Dynorphin A as a GnRH Pulse Generator Controlling Mammalian Reproduction.
Yoshihisa Uenoyama, Mayuko Nagae, Hitomi Tsuchida, Naoko Inoue, Hiroko Tsukamura

Front Endocrinol (Lausanne)· February 2022

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Direct evidence that KNDy neurons maintain gonadotropin pulses and folliculogenesis as the GnRH pulse generator.
Mayuko Nagae, Yoshihisa Uenoyama, Saki Okamoto, Hitomi Tsuchida, Kana Ikegami

Proc Natl Acad Sci U S A· February 2021

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Conditional kisspeptin neuron-specific Kiss1 knockout with newly generated Kiss1-floxed and Kiss1-Cre mice replicates a hypogonadal phenotype of global Kiss1 knockout mice.
Kana Ikegami, Teppei Goto, Sho Nakamura, Youki Watanabe, Arisa Sugimoto, Mayuko Nagae

J Reprod Dev· August 2020

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Ad libitum feeding triggers puberty onset associated with increases in arcuate Kiss1 and Pdyn expression in growth-retarded rats.
Sutisa Majarune, Pelden Nima, Arisa Sugimoto, Mayuko Nagae, Naoko Inoue

J Reprod Dev· October 2019

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