Publications by authors named "Hitoshi Sakuraba"

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Evaluation of variants detected in newborn screening for Fabry disease using biomarker analysis.
Takaaki Sawada, Jun Kido, Takahiro Tsukimura, Keishin Sugawara, Tomoko Shiga, Hitoshi Sakuraba

Mol Genet Metab Rep· September 2025

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Enzyme replacement therapy using a modified α-N-acetylgalactosaminidase to suppress progressive glycolipid accumulation and escape from antidrug antibody formation in young human NAGA-transgenic/Gla-knockout mice.
Hitoshi Sakuraba, Takahiro Tsukimura, Tomoko Shiga, Seiji Saito, Youichi Tajima

Mol Genet Metab· August 2025

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Use of a mouse-human chimeric anti-α-galactosidase A monoclonal antibody as a reference for measuring serum antidrug antibody titers in patients with Fabry disease.
Takahiro Tsukimura, Daisuke Kami, Tomoko Shiga, Tadayasu Togawa, Satoshi Gojo, Hitoshi Sakuraba

Mol Genet Metab· January 2025

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Comparative study on incorporation of three recombinant human α-galactosidase A drugs (agalsidases) into cultured fibroblasts and organs/tissues of Fabry mice.
Takahiro Tsukimura, Tomoko Shiga, Tadayasu Togawa, Hitoshi Sakuraba

Mol Genet Metab Rep· September 2024

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Effects of switching from agalsidase-α to agalsidase-β on biomarkers, renal and cardiac parameters, and disease severity in fabry disease forming neutralizing antidrug antibodies: a case report.
Hisato Shima, Takahiro Tsukimura, Tomoko Shiga, Tadayasu Togawa, Hitoshi Sakuraba

CEN Case Rep· August 2024

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Profiles of Globotriaosylsphingosine Analogs and Globotriaosylceramide Isoforms Accumulated in Body Fluids from Various Phenotypic Fabry Patients.
Tomoko Shiga, Takahiro Tsukimura, Takao Kubota, Tadayasu Togawa, Hitoshi Sakuraba

Intern Med· June 2024

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Does administration of hydroxychloroquine/amiodarone affect the efficacy of enzyme replacement therapy for Fabry mice?
Takahiro Tsukimura, Koki Saito, Tomoko Shiga, Yasuhiro Ogawa, Hitoshi Sakuraba

Mol Genet Metab Rep· June 2024

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Potential Usefulness of Lifetime Globotriaosylsphingosine Exposure at Diagnosis and Baseline Modified Disease Severity Score in Early-Diagnosed Patients With Fabry Disease.
Junko Hotta, Yukiko Jogu, Haruka Bamba, Yasuhiro Izumiya, Masaharu Kudo, Hitoshi Sakuraba

Cureus· May 2024

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Monitoring of anti-drug antibodies and disease-specific biomarkers in three patients from a Japanese Fabry family treated with enzyme replacement therapy.
Takao Kubota, Takahiro Tsukimura, Tomoko Shiga, Tadayasu Togawa, Hitoshi Sakuraba

CEN Case Rep· May 2023

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Delivery of Therapeutic Molecules by Transplantation of Genome-Edited Induced Pluripotent Stem Cells.
Ittetsu Nakajima, Takahiro Tsukimura, Terumi Ono, Tomoko Shiga, Hiroshi Shitara, Hitoshi Sakuraba

Cell Transplant· May 2023

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Globotriaosylceramide Immunostaining of Myocardium in a Patient With Fabry Disease.
Satoru Yoshida, Hiroaki Kawano, Satoshi Ikeda, Hitoshi Sakuraba, Shinji Okano

Circ J· August 2022

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Genetically Modified Cell Transplantation Through Macroencapsulated Spheroids with Scaffolds to Treat Fabry Disease.
Daisuke Kami, Yosuke Suzuki, Masashi Yamanami, Takahiro Tsukimura, Tadayasu Togawa, Hitoshi Sakuraba

Cell Transplant· March 2022

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Fabry disease associated with multiple myeloma: a case report.
Keika Adachi, Hirobumi Tokuyama, Yoichi Oshima, Tomoaki Itoh, Akinori Hashiguchi, Hitoshi Sakuraba

CEN Case Rep· February 2022

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Screening of Fabry disease in patients with chronic kidney disease in Japan.
Akiko Nagata, Makoto Nasu, Yusuke Kaida, Yosuke Nakayama, Yuka Kurokawa, Hitoshi Sakuraba

Nephrol Dial Transplant· December 2021

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Comparative urinary globotriaosylceramide analysis by thin-layer chromatography-immunostaining and liquid chromatography-tandem mass spectrometry in patients with Fabry disease.
Tomoko Shiga, Takahiro Tsukimura, Yurie Namai, Tadayasu Togawa, Hitoshi Sakuraba

Mol Genet Metab Rep· December 2021

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Erratum to: Screening of Fabry disease in patients with chronic kidney disease in Japan.
Akiko Nagata, Makoto Nasu, Yusuke Kaida, Yosuke Nakayama, Yuka Kurokawa, Hitoshi Sakuraba

Nephrol Dial Transplant· November 2021

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Does administration of hydroxychloroquine/amiodarone accelerate accumulation of globotriaosylceramide and globotriaosylsphingosine in Fabry mice?
Takahiro Tsukimura, Tomoko Shiga, Koki Saito, Yasuhiro Ogawa, Hitoshi Sakuraba

Mol Genet Metab Rep· September 2021

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Cell Transplantation Combined with Recombinant Collagen Peptides for the Treatment of Fabry Disease.
Daisuke Kami, Masashi Yamanami, Takahiro Tsukimura, Hideki Maeda, Tadayasu Togawa, Hitoshi Sakuraba

Cell Transplant· July 2021

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[Glial cells and pharmacological targets in Sandhoff disease].
Yasuhiro Ogawa, Hitoshi Sakuraba, Kazuhiko Oishi

Nihon Yakurigaku Zasshi· July 2021

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Surface plasmon resonance analysis of complex formation of therapeutic recombinant lysosomal enzymes with domain 9 of human cation-independent mannose 6-phosphate receptor.
Minori Kanzaki, Takahiro Tsukimura, Yasunori Chiba, Hitoshi Sakuraba, Tadayasu Togawa

Mol Genet Metab Rep· December 2020

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Anti-drug antibody formation in Japanese Fabry patients following enzyme replacement therapy.
Takahiro Tsukimura, Yuya Tayama, Tomoko Shiga, Kanako Hirai, Tadayasu Togawa, Hitoshi Sakuraba

Mol Genet Metab Rep· December 2020

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A cDNA analysis disclosed the discordance of genotype-phenotype correlation in a patient with attenuated MPS II and a 76-base deletion in the gene for iduronate-2-sulfatase.
Yasuyuki Fukuhara, Ai Miura, Narutoshi Yamazaki, Tetsumin So, Motomichi Kosuga, Hitoshi Sakuraba

Mol Genet Metab Rep· December 2020

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Abnormal organization during neurodevelopment in a mouse model of Sandhoff disease.
Yasuhiro Ogawa, Yayoi Sasanuma, Shuhei Shitara, Asuna Koshizuka, Rieko Okada, Hitoshi Sakuraba

Neurosci Res· June 2020

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Effectiveness of immunosuppressive therapy for nephrotic syndrome in a patient with late-onset Fabry disease: a case report and literature review.
Hironobu Fujisawa, Yosuke Nakayama, Shoichiro Nakao, Ryo Yamamoto, Yuka Kurokawa, Hitoshi Sakuraba

BMC Nephrol· December 2019

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Fabry disease in a Japanese population-molecular and biochemical characteristics.
Hitoshi Sakuraba, Takahiro Tsukimura, Tadayasu Togawa, Toshie Tanaka, Tomoko Ohtsuka

Mol Genet Metab Rep· December 2018

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