Publications by authors named "Tomoko Shiga"

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Evaluation of variants detected in newborn screening for Fabry disease using biomarker analysis.
Takaaki Sawada, Jun Kido, Takahiro Tsukimura, Keishin Sugawara, Tomoko Shiga

Mol Genet Metab Rep· September 2025

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Enzyme replacement therapy using a modified α-N-acetylgalactosaminidase to suppress progressive glycolipid accumulation and escape from antidrug antibody formation in young human NAGA-transgenic/Gla-knockout mice.
Hitoshi Sakuraba, Takahiro Tsukimura, Tomoko Shiga, Seiji Saito, Youichi Tajima

Mol Genet Metab· August 2025

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Use of a mouse-human chimeric anti-α-galactosidase A monoclonal antibody as a reference for measuring serum antidrug antibody titers in patients with Fabry disease.
Takahiro Tsukimura, Daisuke Kami, Tomoko Shiga, Tadayasu Togawa, Satoshi Gojo

Mol Genet Metab· January 2025

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Comparative study on incorporation of three recombinant human α-galactosidase A drugs (agalsidases) into cultured fibroblasts and organs/tissues of Fabry mice.
Takahiro Tsukimura, Tomoko Shiga, Tadayasu Togawa, Hitoshi Sakuraba

Mol Genet Metab Rep· September 2024

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Effects of switching from agalsidase-α to agalsidase-β on biomarkers, renal and cardiac parameters, and disease severity in fabry disease forming neutralizing antidrug antibodies: a case report.
Hisato Shima, Takahiro Tsukimura, Tomoko Shiga, Tadayasu Togawa, Hitoshi Sakuraba

CEN Case Rep· August 2024

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Profiles of Globotriaosylsphingosine Analogs and Globotriaosylceramide Isoforms Accumulated in Body Fluids from Various Phenotypic Fabry Patients.
Tomoko Shiga, Takahiro Tsukimura, Takao Kubota, Tadayasu Togawa, Hitoshi Sakuraba

Intern Med· June 2024

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Does administration of hydroxychloroquine/amiodarone affect the efficacy of enzyme replacement therapy for Fabry mice?
Takahiro Tsukimura, Koki Saito, Tomoko Shiga, Yasuhiro Ogawa, Hitoshi Sakuraba

Mol Genet Metab Rep· June 2024

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Monitoring of anti-drug antibodies and disease-specific biomarkers in three patients from a Japanese Fabry family treated with enzyme replacement therapy.
Takao Kubota, Takahiro Tsukimura, Tomoko Shiga, Tadayasu Togawa, Hitoshi Sakuraba

CEN Case Rep· May 2023

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Delivery of Therapeutic Molecules by Transplantation of Genome-Edited Induced Pluripotent Stem Cells.
Ittetsu Nakajima, Takahiro Tsukimura, Terumi Ono, Tomoko Shiga, Hiroshi Shitara

Cell Transplant· May 2023

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Comparative urinary globotriaosylceramide analysis by thin-layer chromatography-immunostaining and liquid chromatography-tandem mass spectrometry in patients with Fabry disease.
Tomoko Shiga, Takahiro Tsukimura, Yurie Namai, Tadayasu Togawa, Hitoshi Sakuraba

Mol Genet Metab Rep· December 2021

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Does administration of hydroxychloroquine/amiodarone accelerate accumulation of globotriaosylceramide and globotriaosylsphingosine in Fabry mice?
Takahiro Tsukimura, Tomoko Shiga, Koki Saito, Yasuhiro Ogawa, Hitoshi Sakuraba

Mol Genet Metab Rep· September 2021

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Simultaneous self-monitoring comparison of a supine algorithm-equipped wrist nocturnal home blood pressure monitoring device with an upper arm device.
Kazuomi Kario, Naoko Tomitani, Chie Iwashita, Tomoko Shiga, Hiroshi Kanegae

J Clin Hypertens (Greenwich)· April 2021

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Anti-drug antibody formation in Japanese Fabry patients following enzyme replacement therapy.
Takahiro Tsukimura, Yuya Tayama, Tomoko Shiga, Kanako Hirai, Tadayasu Togawa

Mol Genet Metab Rep· December 2020

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Urinary afamin levels are associated with the progression of diabetic nephropathy.
Yasushi Kaburagi, Eri Takahashi, Hiroshi Kajio, Shigeo Yamashita, Ritsuko Yamamoto-Honda, Tomoko Shiga

Diabetes Res Clin Pract· January 2019

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Fabry disease in a Japanese population-molecular and biochemical characteristics.
Hitoshi Sakuraba, Takahiro Tsukimura, Tadayasu Togawa, Toshie Tanaka, Tomoko Ohtsuka, Tomoko Shiga

Mol Genet Metab Rep· December 2018

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Proteomic analysis of serum biomarkers for prediabetes using the Long-Evans Agouti rat, a spontaneous animal model of type 2 diabetes mellitus.
Eri Takahashi, Hiroyuki Unoki-Kubota, Yukiko Shimizu, Tadashi Okamura, Wakiko Iwata, Tomoko Shiga

J Diabetes Investig· September 2017

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[Obesity, metabolic syndrome].
Tomoko Shiga

Nihon Rinsho· August 2016

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Multicenter investigation of lifestyle-related diseases and visceral disorders in thalidomide embryopathy at around 50 years of age.
Tomoko Shiga, Takuro Shimbo, Atsuto Yoshizawa

Birth Defects Res A Clin Mol Teratol· September 2015

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Increased serum leukocyte cell-derived chemotaxin 2 (LECT2) levels in obesity and fatty liver.
Akinori Okumura, Hiroyuki Unoki-Kubota, Yumi Matsushita, Tomoko Shiga, Yuriko Moriyoshi

Biosci Trends· December 2013

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Nonalcoholic fatty liver is a risk factor for postprandial hyperglycemia, but not for impaired fasting glucose.
Tomoko Shiga, Yuriko Moriyoshi, Hikaru Nagahara, Keiko Shiratori

J Gastroenterol· August 2009

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An analysis of risk factors for asymptomatic cerebral infarction.
Tomoko Shiga, Kiyoshi Owada, Tatsuo Hoshino, Hikaru Nagahara, Keiko Shiratori

Intern Med· January 2008

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