Publications by authors named "Hitoshi Toyoda"

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Combination therapy with levofloxacin and the probiotic Clostridium butyricum MIYAIRI 588 enhances immune checkpoint inhibitor efficacy.
Kohei Tajima, Masahiro Hosonuma, Eiji Funayama, Junya Isobe, Yuta Baba, Hitoshi Toyoda

Int J Cancer· September 2025

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Inosine shapes PD-1 blockade responses and synergizes with dual PD-1/CTLA-4 immunotherapy to enhance antitumor immunity.
Yoichiro Narikawa, Atsuo Kuramasu, Masahiro Hosonuma, Masakazu Murayama, Eiji Funayama, Hitoshi Toyoda

Cancer Immunol Immunother· August 2025

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Combination therapy with cetirizine and anti-PD-1 antibody suppresses colitis-induced colon tumor formation in mice.
Yuki Maruyama, Masahiro Hosonuma, Hitoshi Toyoda, Eiji Funayama, Akiko Sasaki

Eur J Pharmacol· July 2025

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and are associated with aging of the gut microbiota and affect the efficacy of immune checkpoint inhibitors.
Yuya Hirasawa, Junya Isobe, Masahiro Hosonuma, Toshiaki Tsurui, Yuta Baba, Hitoshi Toyoda

Front Immunol· June 2025

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Ki-67 expression in anti-programmed cell death protein-1 antibody-bound CD8 T cells as a predictor of clinical benefit.
Toshiaki Tsurui, Masahiro Hosonuma, Aya Sasaki, Yuuki Maruyama, Yasunobu Amari, Hitoshi Toyoda

Discov Oncol· March 2025

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Oral administration of Bifidobacterium longum and Bifidobacterium infantis ameliorates cefcapene pivoxil-induced attenuation of anti-programmed cell death protein-1 antibody action in mice.
Eiji Funayama, Masahiro Hosonuma, Kohei Tajima, Junya Isobe, Yuta Baba, Hitoshi Toyoda

Biomed Pharmacother· January 2025

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MHC class I polypeptide-related sequence B shedding modulates pancreatic tumor immunity via the activation of NKG2D T cells.
Hitoshi Toyoda, Atsuo Kuramasu, Masahiro Hosonuma, Masakazu Murayama, Yoichiro Narikawa

Sci Rep· October 2024

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Isobutyric acid enhances the anti-tumour effect of anti-PD-1 antibody.
Masakazu Murayama, Masahiro Hosonuma, Atsuo Kuramasu, Sei Kobayashi, Akiko Sasaki, Hitoshi Toyoda

Sci Rep· May 2024

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Nivolumab receptor occupancy on effector regulatory T cells predicts clinical benefit.
Masahiro Hosonuma, Yuya Hirasawa, Atsuo Kuramasu, Masakazu Murayama, Yoichiro Narikawa, Hitoshi Toyoda

Cancer Sci· March 2024

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Butyricimonas is a key gut microbiome component for predicting postoperative recurrence of esophageal cancer.
Koji Otsuka, Junya Isobe, Yoshiyuki Asai, Tomohisa Nakano, Kouya Hattori, Hitoshi Toyoda

Cancer Immunol Immunother· January 2024

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and predict immune-related adverse events and efficacy of immune checkpoint inhibitor.
Kazuyuki Hamada, Junya Isobe, Kouya Hattori, Masahiro Hosonuma, Yuta Baba, Hitoshi Toyoda

Front Immunol· May 2023

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A novel homocysteine-responsive gene, smap8, modulates mitogenesis in rat vascular smooth muscle cells.
Shinichi Nishimoto, Junko Tawara, Hitoshi Toyoda, Kunihiro Kitamura, Toshi Komurasaki

Eur J Biochem· June 2003

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Identification of a novel smooth muscle associated protein, smap2, upregulated during neointima formation in a rat carotid endarterectomy model.
Shinichi Nishimoto, Yuko Hamajima, Yoshihisa Toda, Hitoshi Toyoda, Kunihiro Kitamura

Biochim Biophys Acta· June 2002

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Mechanism of growth promoting activity of epiregulin in primary cultures of rat hepatocytes.
Toshi Komurasaki, Hitoshi Toyoda, Daisuke Uchida, Nobuo Nemoto

Growth Factors· June 2002

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