Publications by authors named "Ho Pan Sham"

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The gut-skin axis: a bi-directional, microbiota-driven relationship with therapeutic potential.
Maira Jimenez-Sanchez, Larissa S Celiberto, Hyungjun Yang, Ho Pan Sham, Bruce A Vallance

Gut Microbes· December 2025

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TYK2 inhibition enhances Treg differentiation and function while preventing Th1 and Th17 differentiation.
Karoliina Tuomela, Rosa V Garcia, Dominic A Boardman, Pedram Tavakoli, Maria Ancheta-Schmit, Ho Pan Sham

Cell Rep Med· September 2025

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Multiomics profiling and parenteral nutrition weaning in pediatric patients with intestinal failure: A longitudinal cohort study.
Niklas Tappauf, Yvonne Lamers, Ho Pan Sham, Hannah G Piper

JPEN J Parenter Enteral Nutr· May 2025

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Distinct inactivated bacterial-based immune modulators vary in their therapeutic efficacies for treating disease based on the organ site of pathology.
Shirin Kalyan, Mark Bazett, Ho Pan Sham, Momir Bosiljcic, Beryl Luk

Sci Rep· April 2020

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Immune Stimulation Using a Gut Microbe-Based Immunotherapy Reduces Disease Pathology and Improves Barrier Function in Ulcerative Colitis.
Ho Pan Sham, Mark Bazett, Momir Bosiljcic, Hyungjun Yang, Beryl Luk

Front Immunol· October 2019

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15-epi-Lipoxin A, Resolvin D2, and Resolvin D3 Induce NF-κB Regulators in Bacterial Pneumonia.
Ho Pan Sham, Katherine H Walker, Raja-Elie E Abdulnour, Nandini Krishnamoorthy, David N Douda

J Immunol· April 2018

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Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia.
Jennifer K Colby, Raja-Elie E Abdulnour, Ho Pan Sham, Jesmond Dalli, Romain A Colas

Am J Pathol· July 2016

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Goblet Cell Derived RELM-β Recruits CD4+ T Cells during Infectious Colitis to Promote Protective Intestinal Epithelial Cell Proliferation.
Kirk S B Bergstrom, Vijay Morampudi, Justin M Chan, Ganive Bhinder, Jennifer Lau, Ho Pan Sham

PLoS Pathog· August 2015

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Metalloprotease NleC suppresses host NF-κB/inflammatory responses by cleaving p65 and interfering with the p65/RPS3 interaction.
Andrea Hodgson, Eric M Wier, Kai Fu, Xin Sun, Hongbing Yu, Ho Pan Sham

PLoS Pathog· March 2015

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Intestinal epithelium-specific MyD88 signaling impacts host susceptibility to infectious colitis by promoting protective goblet cell and antimicrobial responses.
Ganive Bhinder, Martin Stahl, Ho Pan Sham, Shauna M Crowley, Vijay Morampudi

Infect Immun· September 2014

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Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens.
Leigh A Knodler, Shauna M Crowley, Ho Pan Sham, Hyungjun Yang, Marie Wrande

Cell Host Microbe· August 2014

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A novel mouse model of Campylobacter jejuni gastroenteritis reveals key pro-inflammatory and tissue protective roles for Toll-like receptor signaling during infection.
Martin Stahl, Jenna Ries, Jenny Vermeulen, Hong Yang, Ho Pan Sham

PLoS Pathog· July 2014

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SIGIRR, a negative regulator of TLR/IL-1R signalling promotes Microbiota dependent resistance to colonization by enteric bacterial pathogens.
Ho Pan Sham, Emily Yi Shan Yu, Muhammet F Gulen, Ganive Bhinder, Martin Stahl

PLoS Pathog· March 2014

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DNBS/TNBS colitis models: providing insights into inflammatory bowel disease and effects of dietary fat.
Vijay Morampudi, Ganive Bhinder, Xiujuan Wu, Chuanbin Dai, Ho Pan Sham

J Vis Exp· February 2014

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CD4+ T cells drive goblet cell depletion during Citrobacter rodentium infection.
Justin M Chan, Ganive Bhinder, Ho Pan Sham, Natasha Ryz, Tina Huang

Infect Immun· December 2013

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The Citrobacter rodentium mouse model: studying pathogen and host contributions to infectious colitis.
Ganive Bhinder, Ho Pan Sham, Justin M Chan, Vijay Morampudi, Kevan Jacobson

J Vis Exp· February 2013

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Active vitamin D (1,25-dihydroxyvitamin D3) increases host susceptibility to Citrobacter rodentium by suppressing mucosal Th17 responses.
Natasha R Ryz, Scott J Patterson, Yiqun Zhang, Caixia Ma, Tina Huang, Ho Pan Sham

Am J Physiol Gastrointest Liver Physiol· December 2012

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Regulated virulence controls the ability of a pathogen to compete with the gut microbiota.
Nobuhiko Kamada, Yun-Gi Kim, Ho Pan Sham, Bruce A Vallance, José L Puente

Science· June 2012

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Innate host responses to enteric bacterial pathogens: a balancing act between resistance and tolerance.
Kirk S Bergstrom, Ho Pan Sham, Maryam Zarepour, Bruce A Vallance

Cell Microbiol· April 2012

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Attaching and effacing bacterial effector NleC suppresses epithelial inflammatory responses by inhibiting NF-κB and p38 mitogen-activated protein kinase activation.
Ho Pan Sham, Stephanie R Shames, Matthew A Croxen, Caixia Ma, Justin M Chan

Infect Immun· September 2011

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Interleukin-11 reduces TLR4-induced colitis in TLR2-deficient mice and restores intestinal STAT3 signaling.
Deanna L Gibson, Marinieve Montero, Mark J Ropeleski, Kirk S B Bergstrom, Caixia Ma, Ho Pan Sham

Gastroenterology· October 2010

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The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling.
Stephanie R Shames, Wanyin Deng, Julian A Guttman, Carmen L de Hoog, Yuling Li, Ho Pan Sham

Cell Microbiol· September 2010

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Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice.
Hui Xiao, Weiguo Yin, Mohammed A Khan, Muhammet F Gulen, Hang Zhou, Ho Pan Sham

Gastroenterology· August 2010

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Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa.
Kirk S B Bergstrom, Vanessa Kissoon-Singh, Deanna L Gibson, Caixia Ma, Marinieve Montero, Ho Pan Sham

PLoS Pathog· May 2010

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The single IgG IL-1-related receptor controls TLR responses in differentiated human intestinal epithelial cells.
Mohammed A Khan, Theodore S Steiner, Ho Pan Sham, Kirk S Bergstrom, Jingtian T Huang

J Immunol· March 2010

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