Publications by authors named "Holly Quach"

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Significance of the Vitamin D Receptor on Crosstalk with Nuclear Receptors and Regulation of Enzymes and Transporters.
Keumhan Noh, Edwin C Y Chow, Holly P Quach, Geny M M Groothuis, Rommel G Tirona

AAPS J· June 2022

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Noteworthy idiosyncrasies of 1α,25-dihydroxyvitamin D kinetics for extrapolation from mouse to man: Commentary.
Keumhan Noh, Qi Joy Yang, Lavtej Sekhon, Holly P Quach, Edwin C Y Chow

Biopharm Drug Dispos· March 2020

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Potencies of vitamin D analogs, 1α-hydroxyvitamin D , 1α-hydroxyvitamin D and 25-hydroxyvitamin D , in lowering cholesterol in hypercholesterolemic mice in vivo.
Holly P Quach, Tamara Dzekic, Paola Bukuroshi, K Sandy Pang

Biopharm Drug Dispos· April 2018

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Alterations in gene expression in vitamin D-deficiency: Down-regulation of liver Cyp7a1 and renal Oat3 in mice.
Holly P Quach, Keumhan Noh, Stacie Y Hoi, Adrie Bruinsma, Geny M M Groothuis

Biopharm Drug Dispos· February 2018

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Highlighting Vitamin D Receptor-Targeted Activities of 1,25-Dihydroxyvitamin D in Mice via Physiologically Based Pharmacokinetic-Pharmacodynamic Modeling.
Qi Joy Yang, Paola Bukuroshi, Holly P Quach, Edwin C Y Chow, K Sandy Pang

Drug Metab Dispos· January 2018

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Disrupted Murine Gut-to-Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models.
Edwin C Y Chow, Holly P Quach, Yueping Zhang, Jason Z Y Wang, David C Evans

J Pharmacol Exp Ther· January 2017

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Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters.
Edwin C Y Chow, Jason Z Ya Wang, Holly P Quach, Hui Tang, David C Evans

Drug Metab Dispos· September 2016

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Physiologically-Based Pharmacokinetic-Pharmacodynamic Modeling of 1α,25-Dihydroxyvitamin D3 in Mice.
Vidya Ramakrishnan, Qi Joy Yang, Holly P Quach, Y Cao, Edwin C Y Chow

Drug Metab Dispos· February 2016

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PKPD modelling to predict altered disposition of 1α,25-dihydroxyvitamin D3 in mice due to dose-dependent regulation of CYP27B1 on synthesis and CYP24A1 on degradation.
Holly P Quach, Qi J Yang, Edwin C Chow, Donald E Mager, Stacie Y Hoi

Br J Pharmacol· July 2015

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Effects of 1α,25-dihydroxyvitamin D3 , the natural vitamin D receptor ligand, on the pharmacokinetics of cefdinir and cefadroxil, organic anion transporter substrates, in rat.
Yu Chul Kim, In-Bong Kim, Chi-Kyoung Noh, Holly P Quach, In-Soo Yoon

J Pharm Sci· November 2014

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Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol.
Edwin C Y Chow, Lilia Magomedova, Holly P Quach, Rucha Patel, Matthew R Durk

Gastroenterology· April 2014

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Low levels of GSTA1 expression are required for Caco-2 cell proliferation.
Humaira Adnan, Holly Quach, Kimberley MacIntosh, Monica Antenos, Gordon M Kirby

PLoS One· June 2013

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Temporal changes in tissue 1α,25-dihydroxyvitamin D3, vitamin D receptor target genes, and calcium and PTH levels after 1,25(OH)2D3 treatment in mice.
Edwin C Y Chow, Holly P Quach, Reinhold Vieth, K Sandy Pang

Am J Physiol Endocrinol Metab· May 2013

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