Publications by authors named "Holly Rees"

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CRISPR-derived genome editing therapies: Progress from bench to bedside.
Holly A Rees, Alex C Minella, Cameron A Burnett, Alexis C Komor, Nicole M Gaudelli

Mol Ther· November 2021

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Rationally Designed Base Editors for Precise Editing of the Sickle Cell Disease Mutation.
S Haihua Chu, Michael Packer, Holly Rees, Dieter Lam, Yi Yu

CRISPR J· April 2021

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Directed evolution of adenine base editors with increased activity and therapeutic application.
Nicole M Gaudelli, Dieter K Lam, Holly A Rees, Noris M Solá-Esteves, Luis A Barrera

Nat Biotechnol· July 2020

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Continuous evolution of SpCas9 variants compatible with non-G PAMs.
Shannon M Miller, Tina Wang, Peyton B Randolph, Mandana Arbab, Max W Shen, Holly A Rees

Nat Biotechnol· April 2020

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Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity.
Yi Yu, Thomas C Leete, David A Born, Lauren Young, Luis A Barrera, Holly A Rees

Nat Commun· April 2020

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A Dimmer-Switch for SpCas9 Activity.
Holly A Rees, Nicole M Gaudelli

CRISPR J· June 2019

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Analysis and minimization of cellular RNA editing by DNA adenine base editors.
Holly A Rees, Christopher Wilson, Jordan L Doman, David R Liu

Sci Adv· May 2019

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Development of hRad51-Cas9 nickase fusions that mediate HDR without double-stranded breaks.
Holly A Rees, Wei-Hsi Yeh, David R Liu

Nat Commun· May 2019

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CRISPResso2 provides accurate and rapid genome editing sequence analysis.
Kendell Clement, Holly Rees, Matthew C Canver, Jason M Gehrke, Rick Farouni

Nat Biotechnol· March 2019

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Base editing: precision chemistry on the genome and transcriptome of living cells.
Holly A Rees, David R Liu

Nat Rev Genet· December 2018

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Publisher Correction: Base editing: precision chemistry on the genome and transcriptome of living cells.
Holly A Rees, David R Liu

Nat Rev Genet· December 2018

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Green fluorescent proteins engineered for cartilage-targeted drug delivery: Insights for transport into highly charged avascular tissues.
Yamini Krishnan, Holly A Rees, Christina P Rossitto, Si-Eun Kim, Han-Hwa K Hung

Biomaterials· November 2018

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Publisher Correction: Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran

Nature· July 2018

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In vivo base editing of post-mitotic sensory cells.
Wei-Hsi Yeh, Hao Chiang, Holly A Rees, Albert S B Edge, David R Liu

Nat Commun· June 2018

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Mechanism of Nonsense-Mediated mRNA Decay Stimulation by Splicing Factor SRSF1.
Isabel Aznarez, Tomoki T Nomakuchi, Jaclyn Tetenbaum-Novatt, Mohammad Alinoor Rahman, Oliver Fregoso, Holly Rees

Cell Rep· May 2018

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Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.
Johnny H Hu, Shannon M Miller, Maarten H Geurts, Weixin Tang, Liwei Chen, Holly A Rees

Nature· April 2018

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Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran

Nature· November 2017

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Phage-assisted continuous evolution of proteases with altered substrate specificity.
Michael S Packer, Holly A Rees, David R Liu

Nat Commun· October 2017

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Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery.
Holly A Rees, Alexis C Komor, Wei-Hsi Yeh, Joana Caetano-Lopes, Matthew Warman

Nat Commun· June 2017

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Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles.
Ming Wang, John A Zuris, Fantao Meng, Holly Rees, Shuo Sun

Proc Natl Acad Sci U S A· March 2016

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Structural and evolutionary versatility in protein complexes with uneven stoichiometry.
Joseph A Marsh, Holly A Rees, Sebastian E Ahnert, Sarah A Teichmann

Nat Commun· March 2015

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