Publications by authors named "Michael Packer"

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Base-editing corrects metabolic abnormalities in a humanized mouse model for glycogen storage disease type-Ia.
Irina Arnaoutova, Yvonne Aratyn-Schaus, Lisa Zhang, Michael S Packer, Hung-Dar Chen

Nat Commun· November 2024

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Cytosine base editing inhibits hepatitis B virus replication and reduces HBsAg expression and .
Elena M Smekalova, Maria G Martinez, Emmanuel Combe, Anuj Kumar, Selam Dejene, Michael S Packer

Mol Ther Nucleic Acids· March 2024

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Identification of Bioactive Peptides from a Protein Hydrolysate Using In Silico and In Vitro Methods to Identify Angiotensin-1-Converting Enzyme (ACE-1) Inhibitory Peptides.
Diane Purcell, Michael A Packer, Maria Hayes

Mar Drugs· January 2023

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Angiotensin-I-Converting Enzyme Inhibitory Activity of Protein Hydrolysates Generated from the Macroalga (Hudson) JV Lamouroux 1813.
Diane Purcell, Michael A Packer, Maria Hayes

Foods· June 2022

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Evaluation of cytosine base editing and adenine base editing as a potential treatment for alpha-1 antitrypsin deficiency.
Michael S Packer, Vivek Chowdhary, Genesis Lung, Lo-I Cheng, Yvonne Aratyn-Schaus

Mol Ther· April 2022

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Adenine base editing reduces misfolded protein accumulation and toxicity in alpha-1 antitrypsin deficient patient iPSC-hepatocytes.
Rhiannon B Werder, Joseph E Kaserman, Michael S Packer, Jonathan Lindstrom-Vautrin, Carlos Villacorta-Martin

Mol Ther· November 2021

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Transvesical robotic excision of a Müllerian duct remnant.
Laura C Kidd, Chinonyerem Okoro, Michael Packer, Gregory Dean, Daniel D Eun

Urol Case Rep· September 2021

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An Enlarged and Infected Prostatic Utricle as a Rare Cause of Lower Urinary Tract Symptoms in Adolescent Males.
Rashida Shakir, Michael G Packer, Zarine R Balsara

Case Rep Pediatr· June 2021

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Rationally Designed Base Editors for Precise Editing of the Sickle Cell Disease Mutation.
S Haihua Chu, Michael Packer, Holly Rees, Dieter Lam, Yi Yu

CRISPR J· April 2021

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Phage-assisted evolution of botulinum neurotoxin proteases with reprogrammed specificity.
Travis R Blum, Hao Liu, Michael S Packer, Xiaozhe Xiong, Pyung-Gang Lee

Science· February 2021

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Aquaculture Production of the Brown Seaweeds and : Applications in Food and Pharmaceuticals.
Diane Purcell-Meyerink, Michael A Packer, Thomas T Wheeler, Maria Hayes

Molecules· February 2021

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Directed evolution of adenine base editors with increased activity and therapeutic application.
Nicole M Gaudelli, Dieter K Lam, Holly A Rees, Noris M Solá-Esteves, Luis A Barrera, Michael S Packer

Nat Biotechnol· July 2020

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A critical control point approach to the removal of chemicals of concern from water for reuse.
Peter J Scales, Kaushalya Wijekoon, Christian Ladwig, Adrian Knight, Mayumi Allinson, Michael Packer

Water Res· September 2019

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Publisher Correction: Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran

Nature· July 2018

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Greenshell™ Mussels: A Review of Veterinary Trials and Future Research Directions.
Charles T Eason, Serean L Adams, Jonathan Puddick, Donato Romanazzi, Matthew R Miller, Michael A Packer

Vet Sci· March 2018

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Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran

Nature· November 2017

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Phage-assisted continuous evolution of proteases with altered substrate specificity.
Michael S Packer, Holly A Rees, David R Liu

Nat Commun· October 2017

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Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.
Alexis C Komor, Kevin T Zhao, Michael S Packer, Nicole M Gaudelli, Amanda L Waterbury

Sci Adv· August 2017

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The biosynthesis of nitrous oxide in the green alga Chlamydomonas reinhardtii.
Maxence Plouviez, David Wheeler, Andy Shilton, Michael A Packer, Patricia A McLenachan

Plant J· July 2017

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Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions.
Y Bill Kim, Alexis C Komor, Jonathan M Levy, Michael S Packer, Kevin T Zhao

Nat Biotechnol· April 2017

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The use of a mucus trap by Dinophysis acuta for the capture of Mesodinium rubrum prey under culture conditions.
Gemma Giménez Papiol, Veronica Beuzenberg, Andrew I Selwood, Lincoln MacKenzie, Michael A Packer

Harmful Algae· September 2016

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Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu

Nature· May 2016

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New insights into the molecular mechanism of the Rab GTPase Sec4p activation.
Fabio C Rinaldi, Michael Packer, Ruth Collins

BMC Struct Biol· August 2015

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Methods for the directed evolution of proteins.
Michael S Packer, David R Liu

Nat Rev Genet· July 2015

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A system for the continuous directed evolution of proteases rapidly reveals drug-resistance mutations.
Bryan C Dickinson, Michael S Packer, Ahmed H Badran, David R Liu

Nat Commun· October 2014

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