Publications by authors named "Hong-May Sim"

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ABC Transporter-Mediated Multidrug-Resistant Cancer.
Haneen Amawi, Hong-May Sim, Amit K Tiwari, Suresh V Ambudkar, Suneet Shukla

Adv Exp Med Biol· October 2019

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A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53.
Jin Huei Wong, Mohammad Alfatah, Mei Fang Sin, Hong May Sim, Chandra S Verma

BMC Biol· November 2017

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Molecular basis of the polyspecificity of P-glycoprotein (ABCB1): recent biochemical and structural studies.
Eduardo E Chufan, Hong-May Sim, Suresh V Ambudkar

Adv Cancer Res· October 2015

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Multiple transport-active binding sites are available for a single substrate on human P-glycoprotein (ABCB1).
Eduardo E Chufan, Khyati Kapoor, Hong-May Sim, Satyakam Singh, Tanaji T Talele

PLoS One· October 2014

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ARRY-334543 reverses multidrug resistance by antagonizing the activity of ATP-binding cassette subfamily G member 2.
De-Shen Wang, Atish Patel, Hong-May Sim, Yun-Kai Zhang, Yi-Jun Wang

J Cell Biochem· August 2014

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Human ABCB1 (P-glycoprotein) and ABCG2 mediate resistance to BI 2536, a potent and selective inhibitor of Polo-like kinase 1.
Chung-Pu Wu, Sung-Han Hsiao, Hong-May Sim, Shi-Yu Luo, Wei-Cherng Tuo

Biochem Pharmacol· October 2013

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Conserved Walker A cysteines 431 and 1074 in human P-glycoprotein are accessible to thiol-specific agents in the apo and ADP-vanadate trapped conformations.
Hong-May Sim, Jaya Bhatnagar, Eduardo E Chufan, Khyati Kapoor, Suresh V Ambudkar

Biochemistry· October 2013

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Overexpression of ATP-binding cassette transporter ABCG2 as a potential mechanism of acquired resistance to vemurafenib in BRAF(V600E) mutant cancer cells.
Chung-Pu Wu, Hong-May Sim, Yang-Hui Huang, Yen-Chen Liu, Sung-Han Hsiao

Biochem Pharmacol· February 2013

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Saracatinib (AZD0530) is a potent modulator of ABCB1-mediated multidrug resistance in vitro and in vivo.
Ke-Jun Liu, Jie-Hua He, Xiao-Dong Su, Hong-May Sim, Jing-Dun Xie

Int J Cancer· January 2013

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Neratinib reverses ATP-binding cassette B1-mediated chemotherapeutic drug resistance in vitro, in vivo, and ex vivo.
Xiao-qin Zhao, Jing-dun Xie, Xing-gui Chen, Hong May Sim, Xu Zhang

Mol Pharmacol· July 2012

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In vitro and in vivo modulation of ABCG2 by functionalized aurones and structurally related analogs.
Hong-May Sim, Chung-Pu Wu, Suresh V Ambudkar, Mei-Lin Go

Biochem Pharmacol· December 2011

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Synthesis and antimicrobial activity of N¹-benzyl or N¹-benzyloxy-1,6-dihydro-1,3,5-triazine-2,4-diamines.
Xiang Ma, Soo-Tong Tan, Chai-Ling Khoo, Hong-May Sim, Lai-Wah Chan

Bioorg Med Chem Lett· September 2011

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Aurones as modulators of ABCG2 and ABCB1: synthesis and structure-activity relationships.
Hong May Sim, Ker Yun Loh, Wee Kiang Yeo, Chong Yew Lee, Mei Lin Go

ChemMedChem· April 2011

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Dimethoxyaurones: Potent inhibitors of ABCG2 (breast cancer resistance protein).
Hong-May Sim, Chong-Yew Lee, Pui Lai Rachel Ee, Mei-Lin Go

Eur J Pharm Sci· November 2008

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