Publications by authors named "Hong-Sheng Lee"

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Role of C/EBPβ/STAT3/AP-1 transcriptional complex formation in thrombin-induced connective tissue growth factor expression in human lung fibroblasts.
Hung-Sheng Hua, Yi-Ting Huang, Hong-Sheng Lee, Chia-Hao Liu, Wei Chao

Eur J Pharmacol· November 2025

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Involvement of ADAM17-dependent MUC1-CT activation in TGF-β-induced EZH2 expression in human lung fibroblasts and in ovalbumin-induced airway fibrosis in mice.
Hung-Sheng Hua, Jing-Jing You, Yu-Chih Wu, Jing-Yun Chen, Hong-Sheng Lee

Biochem Pharmacol· September 2025

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MPT0E028, a novel pan-HDAC inhibitor, prevents pulmonary fibrosis through inhibition of TGF-β-induced CTGF expression in human lung fibroblasts: Involvement of MKP-1 activation.
Chia-Hao Liu, Hong-Sheng Lee, Jing-Ping Liou, Hung-Sheng Hua, Wun-Hao Cheng

Eur J Pharmacol· August 2024

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Endothelin-1 induces connective tissue growth factor expression in human lung fibroblasts by disrupting HDAC2/Sin3A/MeCP2 corepressor complex.
Hung-Sheng Hua, Heng-Ching Wen, Hong-Sheng Lee, Chih-Ming Weng, Fara Silvia Yuliani

J Biomed Sci· June 2023

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A Potent Histone Deacetylase Inhibitor MPT0E028 Mitigates Emphysema Severity via Components of the Hippo Signaling Pathway in an Emphysematous Mouse Model.
Lu-Yang Yeh, Yu-Ting Fang, Hong-Sheng Lee, Chia-Hao Liu, You-Yin Chen

Front Med (Lausanne)· May 2022

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Synthesis and biological evaluation of phenothiazine derivative-containing hydroxamic acids as potent class II histone deacetylase inhibitors.
Kai-Cheng Hsu, Jung-Chun Chu, Hui-Ju Tseng, Chia-I Liu, Hao-Ching Wang, Hong-Sheng Lee

Eur J Med Chem· July 2021

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Histone deacetylase 7 mediates endothelin-1-induced connective tissue growth factor expression in human lung fibroblasts through p300 and activator protein-1 activation.
Hung-Sheng Hua, Heng-Ching Wen, Chih-Ming Weng, Hong-Sheng Lee, Bing-Chang Chen

J Biomed Sci· May 2021

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induces connective tissue growth factor expression through the TLR2-JNK-AP-1 pathway in human lung fibroblasts.
Hong-Sheng Lee, Hung-Sheng Hua, Cheng-Hui Wang, Ming-Chih Yu, Bing-Chang Chen

FASEB J· November 2019

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