Publications by authors named "Hui-Ju Tseng"

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Exploring diarylheptanoid derivatives to target LIMK1 as potential agents against colorectal cancer.
Liang-Chieh Chen, Tung-Cheng Chang, Hui-Ju Tseng, Jung-Chun Chu, Yun-Yi Huang

J Enzyme Inhib Med Chem· December 2025

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Combined HDAC8 and checkpoint kinase inhibition induces tumor-selective synthetic lethality in preclinical models.
Ting-Yu Chang, Yan Yan, Zih-Yao Yu, Moeez Rathore, Nian-Zhe Lee, Hui-Ju Tseng

J Clin Invest· October 2024

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Synthesis and biological evaluation of C-4 substituted phenoxazine-bearing hydroxamic acids with potent class II histone deacetylase inhibitory activities.
Jung-Chun Chu, Hui-Ju Tseng, Sung-Bau Lee, Kai-Cheng Hsu, Ling-Wei Hsin

J Enzyme Inhib Med Chem· December 2023

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Design, synthesis, and biological activity of dual monoamine oxidase A and heat shock protein 90 inhibitors, N-Methylpropargylamine-conjugated 4-isopropylresorcinol for glioblastoma.
Hui-Ju Tseng, Suddhasatwa Banerjee, Bin Qian, Mei-Jung Lai, Tung-Yun Wu

Eur J Med Chem· August 2023

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Design, synthesis, and biological evaluation of indolin-2-one derivatives as novel cyclin-dependent protein kinase 8 (CDK8) inhibitors.
Jui-Yi Hsu, Kai-Cheng Hsu, Ching Sun, Ching-Hsuan Chou, Tony Eight Lin, Hui-Ju Tseng

Biomed Pharmacother· March 2023

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Pharmacological and mechanistic study of PS1, a Pdia4 inhibitor, in β-cell pathogenesis and diabetes in db/db mice.
Hui-Ju Tseng, Wen-Chu Chen, Tien-Fen Kuo, Greta Yang, Ching-Shan Feng

Cell Mol Life Sci· March 2023

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O-methylated flavonol as a multi-kinase inhibitor of leukemogenic kinases exhibits a potential treatment for acute myeloid leukemia.
Shih-Chung Yen, Yi-Wen Wu, Cheng-Chiao Huang, Min-Wu Chao, Huang-Ju Tu, Hui-Ju Tseng

Phytomedicine· June 2022

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Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approach.
Shih-Chung Yen, Liang-Chieh Chen, Han-Li Huang, Wei-Chun HuangFu, Yi-Ying Chen, Hui-Ju Tseng

Bioorg Chem· April 2022

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Synthesis and biological evaluation of phenothiazine derivative-containing hydroxamic acids as potent class II histone deacetylase inhibitors.
Kai-Cheng Hsu, Jung-Chun Chu, Hui-Ju Tseng, Chia-I Liu, Hao-Ching Wang

Eur J Med Chem· July 2021

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Synthesis of Yakuchinone B-Inspired Inhibitors against Islet Amyloid Polypeptide Aggregation.
Jui-Yi Hsu, Ashish Rao Sathyan, Kai-Cheng Hsu, Liang-Chieh Chen, Cheng-Chung Yen, Hui-Ju Tseng

J Nat Prod· April 2021

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Investigation of Selected Flavonoid Derivatives as Potent FLT3 Inhibitors for the Potential Treatment of Acute Myeloid Leukemia.
Shih-Chung Yen, Liang-Chieh Chen, Han-Li Huang, Sin-Ting Ngo, Yi-Wen Wu, Hui-Ju Tseng

J Nat Prod· January 2021

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Biological Evaluation of Selected Flavonoids as Inhibitors of MNKs Targeting Acute Myeloid Leukemia.
Liang-Chieh Chen, Han-Li Huang, Wei-Chun HuangFu, Shih-Chung Yen, Sin-Ting Ngo, Hui-Ju Tseng

J Nat Prod· October 2020

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Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer's disease.
Hui-Ju Tseng, Mei-Hsiang Lin, Young-Ji Shiao, Ying-Chen Yang, Jung-Chun Chu

Eur J Med Chem· April 2020

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Design of Diarylheptanoid Derivatives as Dual Inhibitors Against Class IIa Histone Deacetylase and β-amyloid Aggregation.
Liang-Chieh Chen, Hui-Ju Tseng, Chang-Yi Liu, Yun-Yi Huang, Cheng-Chung Yen

Front Pharmacol· July 2018

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Total Synthesis and Metabolic Stability of Hispidulin and Its d-Labelled Derivative.
Liang-Chieh Chen, Kai-Cheng Hsu, Lih-Chu Chiou, Hui-Ju Tseng, Wei-Jan Huang

Molecules· November 2017

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Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach.
Kai-Cheng Hsu, Chang-Yi Liu, Tony Eight Lin, Jui-Hua Hsieh, Tzu-Ying Sung, Hui-Ju Tseng

Sci Rep· June 2017

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