Publications by authors named "Honghe Wan"

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Long-Acting Tumor-Activated Prodrug of a TGFβR Inhibitor.
Yong Zhang, Karen E Parrish, David R Tortolani, Michael A Poss, Audris Huang, Honghe Wan, Jesse Swanson

J Med Chem· November 2021

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Substituted diaryl ether compounds as retinoic acid-related orphan Receptor-γt (RORγt) agonists.
Zheming Ruan, Peter K Park, Donna Wei, Ashok Purandare, Honghe Wan

Bioorg Med Chem Lett· March 2021

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Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9).
Christopher P Mussari, Dharmpal S Dodd, Ratna Kumar Sreekantha, Laxman Pasunoori, Honghe Wan

ACS Med Chem Lett· September 2020

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Structure-Based Design of Selective Janus Kinase 2 Imidazo[4,5-d]pyrrolo[2,3-b]pyridine Inhibitors.
Amy C Hart, Gretchen M Schroeder, Honghe Wan, James Grebinski, Jennifer Inghrim

ACS Med Chem Lett· August 2015

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Discovery of a Highly Selective JAK2 Inhibitor, BMS-911543, for the Treatment of Myeloproliferative Neoplasms.
Honghe Wan, Gretchen M Schroeder, Amy C Hart, Jennifer Inghrim, James Grebinski

ACS Med Chem Lett· August 2015

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Pyrrolo[1,2-f]triazines as JAK2 inhibitors: achieving potency and selectivity for JAK2 over JAK3.
Lalgudi S Harikrishnan, Muthoni G Kamau, Honghe Wan, Jennifer A Inghrim, Kurt Zimmermann

Bioorg Med Chem Lett· March 2011

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Benzo[d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)--Hit to Lead studies.
Honghe Wan, Tram Huynh, Suhong Pang, Jieping Geng, Wayne Vaccaro

Bioorg Med Chem Lett· September 2009

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Core exploration in optimization of chemokine receptor CCR4 antagonists.
Ashok V Purandare, Honghe Wan, John E Somerville, Christine Burke, Wayne Vaccaro

Bioorg Med Chem Lett· February 2007

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Optimization of CCR4 antagonists: side-chain exploration.
Ashok V Purandare, Honghe Wan, Aiming Gao, John Somerville, Christine Burke

Bioorg Med Chem Lett· January 2006

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Identification of chemokine receptor CCR4 antagonist.
Ashok V Purandare, Aiming Gao, Honghe Wan, John Somerville, Christine Burke

Bioorg Med Chem Lett· May 2005

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Identification of a potent and rapidly reversible inhibitor of the 20S-proteasome.
Ashok V Purandare, Honghe Wan, Naomi Laing, Khalid Benbatoul, Wayne Vaccaro

Bioorg Med Chem Lett· September 2004

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Chiral nonracemic alpha-alkylidene and alpha-silylidene cyclopentenones from chiral allenes using an intramolecular allenic Pauson-Khand-type cycloaddition.
Kay M Brummond, Angela D Kerekes, Honghe Wan

J Org Chem· July 2002

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