Publications by authors named "Howard Leung"

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Histopathology-based assessment of the tumour microenvironment in gastrointestinal cancers: practical approaches to prognostication and treatment stratification.
Shelly Yunbi Ni, Howard Ho-Wai Leung, Anthony Wing-Hung Chan

J Pathol Clin Res· November 2025

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Contrast enhanced EUS versus conventional EUS guided fine needle biopsy with macroscopic on-site evaluation for solid pancreatic lesions: a multicenter randomized trial.
Charing C N Chong, Dario Ligresti, Tae Hyeon Kim, Ilaria Tarantino, Mario Traina, Howard H W Leung

Gastrointest Endosc· October 2025

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FADD Activation in Hepatocellular Carcinoma Potentiates CD8+ T-cell Responses and Sensitizes to Immune Checkpoint Inhibitors.
Jiahuan Lu, Thomas Ting-Hei Chan, Yun Wang, Jingya Wang, Zhewen Xiong, Howard H W Leung

Cancer Res· September 2025

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Patient-derived organoids inform pharmacogenomic vulnerabilities in liver cancer.
Alissa Michelle Wong, Hao Huang, Aikha Melissa Wong, Howard Ho Wai Leung, Winnie Wing Yan Cheung

JHEP Rep· July 2025

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Tetrandrine regulates NAADP-mediated calcium signaling through a LIMP-2-dependent and sphingosine-mediated mechanism.
Wing-Cheung Chan, Qian Zhao, Koon Ho Wong, Hok-Him Tang, Daniel Kam-Wah Mok, Howard Ho-Wai Leung, Franco King-Chi Leung

Nat Commun· July 2025

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Evaluation of breast-specific marker expression in metastatic breast cancers: Correlation with subtype switch.
Ronald Chan, Howard Leung, Joshua Li, Ivan Poon, Julia Y Tsang

Histopathology· March 2025

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Pharmacological activation of STAT1-GSDME pyroptotic circuitry reinforces epigenetic immunotherapy for hepatocellular carcinoma.
Yalin Tu, Haoran Wu, Chengpeng Zhong, Yan Liu, Zhewen Xiong, Howard Leung

Gut· March 2025

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Deep Spatio-Temporal Network for Low-SNR Cryo-EM Movie Frame Enhancement.
Xiaoya Chong, Howard Leung, Qing Li, Jianhua Yao, Niyun Zhou

IEEE/ACM Trans Comput Biol Bioinform· October 2024

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Consensus statements on endoscopic ultrasound-guided tissue acquisition. Guidelines from the Asian Endoscopic Ultrasound Group.
Charing Ching-Ning Chong, Rapat Pittayanon, Nonthalee Pausawasdi, Vikram Bhatia, Nozomi Okuno, Howard Ho Wai Leung

Dig Endosc· August 2024

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PPP1R15A-expressing monocytic MDSCs promote immunosuppressive liver microenvironment in fibrosis-associated hepatocellular carcinoma.
Xiaoyu Liu, Man Liu, Haoran Wu, Wenshu Tang, Weiqin Yang, Howard H W Leung

JHEP Rep· July 2024

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Performance of continuous controlled attenuation parameter and liver stiffness measurement by the novel SmartExam in metabolic dysfunction-associated steatotic liver disease.
Sherlot J Song, Asako Nogami, Lilian Y Liang, Masato Yoneda, Howard H W Leung

Liver Int· May 2024

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Machine-learning model comprising five clinical indices and liver stiffness measurement can accurately identify MASLD-related liver fibrosis.
Rong Fan, Ning Yu, Guanlin Li, Tamoore Arshad, Wen-Yue Liu, Howard Ho-Wai Leung

Liver Int· March 2024

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Aspiration cytology of liver abscess uncovering metastatic rectal mucosal melanoma-A case report.
Joanna K M Ng, Howard H W Leung, Joshua J X Li

Cytopathology· January 2024

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MAFLD fibrosis score: Using routine measures to identify advanced fibrosis in metabolic-associated fatty liver disease.
Johnny T K Cheung, Xinrong Zhang, Grace Lai-Hung Wong, Terry Cheuk-Fung Yip, Huapeng Lin, Howard Ho-Wai Leung

Aliment Pharmacol Ther· December 2023

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Deep learning-based phenotyping reclassifies combined hepatocellular-cholangiocarcinoma.
Julien Calderaro, Narmin Ghaffari Laleh, Qinghe Zeng, Pascale Maille, Loetitia Favre, Howard Ho Wai Leung

Nat Commun· December 2023

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Case 39-2023: A 43-Year-Old Woman with Chronic Diarrhea, Hair Loss, and Nail and Skin Changes.
Jimmy C T Lai, W K Claudia Wu, W S Agnes Chan, Louis H S Lau, Howard H W Leung

N Engl J Med· December 2023

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aMAP Score and Its Combination With Liver Stiffness Measurement Accurately Assess Liver Fibrosis in Chronic Hepatitis B Patients.
Rong Fan, Guanlin Li, Ning Yu, Xiujuan Chang, Tamoore Arshad, Howard Ho-Wai Leung

Clin Gastroenterol Hepatol· November 2023

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TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk.
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M Wong, Howard H Leung

Hepatology· September 2023

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Targeting PPAR-gamma counteracts tumour adaptation to immune-checkpoint blockade in hepatocellular carcinoma.
Zhewen Xiong, Stephen Lam Chan, Jingying Zhou, Joaquim S L Vong, Tsz Tung Kwong, Howard H W Leung

Gut· September 2023

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M-Denoiser: Unsupervised image denoising for real-world optical and electron microscopy data.
Xiaoya Chong, Min Cheng, Wenqi Fan, Qing Li, Howard Leung

Comput Biol Med· September 2023

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Steatosis, HBV-related HCC, cirrhosis, and HBsAg seroclearance: A systematic review and meta-analysis.
Xianhua Mao, Ka Shing Cheung, Chengzhi Peng, Lung-Yi Mak, Ho Ming Cheng, Howard H-W Leung

Hepatology· May 2023

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N-terminal propeptide of type 3 collagen-based sequential algorithm can identify high-risk steatohepatitis and fibrosis in MAFLD.
Liang-Jie Tang, Gang Li, Mohammed Eslam, Pei-Wu Zhu, Sui-Dan Chen, Howard Ho-Wai Leung

Hepatol Int· February 2023

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Evaluation of a group-based sensorimotor intervention programme to improve Chinese handwriting of primary school students.
Cecilia W P Li-Tsang, Tim M H Li, C N Yang, Phoebe P P Cheung, K Y Au, Howard W H Leung

Heliyon· February 2023

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Nestin as a diagnostic and prognostic marker for combined hepatocellular-cholangiocarcinoma.
Julien Calderaro, Luca Di Tommaso, Pascale Maillé, Aurélie Beaufrère, Cong Trung Nguyen, Howard Ho Wai Leung

J Hepatol· December 2022

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A Two-stream Convolutional Network for Musculoskeletal and Neurological Disorders Prediction.
Manli Zhu, Qianhui Men, Edmond S L Ho, Howard Leung, Hubert P H Shum

J Med Syst· October 2022

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