Publications by authors named "Yalin Tu"

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FADD Activation in Hepatocellular Carcinoma Potentiates CD8+ T-cell Responses and Sensitizes to Immune Checkpoint Inhibitors.
Jiahuan Lu, Thomas Ting-Hei Chan, Yun Wang, Jingya Wang, Zhewen Xiong, Yalin Tu

Cancer Res· September 2025

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Pharmacological activation of STAT1-GSDME pyroptotic circuitry reinforces epigenetic immunotherapy for hepatocellular carcinoma.
Yalin Tu, Haoran Wu, Chengpeng Zhong, Yan Liu, Zhewen Xiong, Tsz Tung Kwong

Gut· March 2025

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Targeting PPAR-gamma counteracts tumour adaptation to immune-checkpoint blockade in hepatocellular carcinoma.
Zhewen Xiong, Stephen Lam Chan, Jingying Zhou, Joaquim S L Vong, Tsz Tung Kwong, Yalin Tu

Gut· September 2023

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The mitotic regulator RCC2 promotes glucose metabolism through BACH1-dependent transcriptional upregulation of hexokinase II in glioma.
Tian Liu, Yubing Wang, Yiwei Wang, Stanley Kwok-Kuen Cheung, Penelope Mei-Yu Or, Yalin Tu

Cancer Lett· November 2022

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PT109, a novel multi-kinase inhibitor suppresses glioblastoma multiforme through cell reprogramming: Involvement of PTBP1/PKM1/2 pathway.
Yang Yang, Yalin Tu, Junfeng Lu, Qiuhe Chen, Zeyu Zhu

Eur J Pharmacol· April 2022

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Sirtuin 7 super-enhancer drives epigenomic reprogramming in hepatocarcinogenesis.
Feng Wu, Liangliang Xu, Yalin Tu, Otto Kw Cheung, Lemuel Lm Szeto

Cancer Lett· January 2022

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Design, Synthesis, and Evaluation of VHL-Based EZH2 Degraders to Enhance Therapeutic Activity against Lymphoma.
Yalin Tu, Yameng Sun, Shuang Qiao, Yao Luo, Panpan Liu

J Med Chem· July 2021

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A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinoma.
Weiqin Yang, Yu Feng, Jingying Zhou, Otto Ka-Wing Cheung, Jianquan Cao, Yalin Tu

Sci Transl Med· April 2021

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Discovery of a novel small molecule PT109 with multi-targeted effects against Alzheimer's disease in vitro and in vivo.
Qiuhe Chen, Yalin Tu, Shinghung Mak, Jingkao Chen, Junfeng Lu

Eur J Pharmacol· September 2020

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Dkk1 exacerbates doxorubicin-induced cardiotoxicity by inhibiting the Wnt/β-catenin signaling pathway.
Liying Liang, Yalin Tu, Jing Lu, Panxia Wang, Zhen Guo

J Cell Sci· May 2019

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L-F001, a novel multifunctional ROCK inhibitor, suppresses neuroinflammation in vitro and in vivo: Involvement of NF-κB inhibition and Nrf2 pathway activation.
Jingkao Chen, Wei Yin, Yalin Tu, Shengnan Wang, Xiaohong Yang

Eur J Pharmacol· July 2017

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Inhibition of AGEs/RAGE/Rho/ROCK pathway suppresses non-specific neuroinflammation by regulating BV2 microglial M1/M2 polarization through the NF-κB pathway.
Jingkao Chen, Zhaowei Sun, Minghua Jin, Yalin Tu, Shengnan Wang

J Neuroimmunol· April 2017

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IDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway.
Kaishu Li, Leping Ouyang, Mingliang He, Ming Luo, Wangqing Cai, Yalin Tu

Oncotarget· April 2017

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PT93, a novel caffeic acid amide derivative, suppresses glioblastoma cells migration, proliferation and MMP-2/-9 expression.
Kaishu Li, Yalin Tu, Qingyu Liu, Ying Ouyang, Mingliang He

Oncol Lett· March 2017

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Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease.
Ziwei Chen, Maria Digiacomo, Yalin Tu, Qiong Gu, Shengnan Wang

Eur J Med Chem· January 2017

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Effects of melatonin and its analogues on neural stem cells.
Jiaqi Chu, Yalin Tu, Jingkao Chen, Dunxian Tan, Xingguo Liu

Mol Cell Endocrinol· January 2016

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