Publications by authors named "Howard Mcleod"

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Propranolol metabolite and enantiomers affect colorectal cancer development by inhibiting MAPK pathway and downregulating PD-1 expression.
Hanying Yi, Yingying Dai, Cuiyu Chen, Wenjuan Ma, Yu Zhang, Howard L Mcleod

Int Immunopharmacol· February 2026

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A two-stage genome-wide association study to identify novel genetic loci associated with irAEs in lung cancer patients receiving PD-1/PD-L1 inhibitors.
Lei She, Juan Chen, Jun-Yan Liu, Jia-Si Liu, Xiao-Ping Tang, Howard L McLeod

Cancer Lett· November 2025

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Advancing the science of genomic learning healthcare systems.
Teri A Manolio, Renee Rider, Carol J Bult, Rex L Chisholm, Patricia A Deverka, Howard L McLeod

Learn Health Syst· October 2025

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Optimization of oncology biomarker testing in managed care: Best practices and consensus recommendations from an AMCP Market Insights program.
Diana Brixner, Terry Richardson, Catherine M Lockhart, Scott Ramsey, John Fox, Howard Mcleod

J Manag Care Spec Pharm· June 2025

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ADRB2 inhibition suppresses cancer immune evasion by regulating tumor SOX10-PD-L1 axis and T cell function.
Yu Zhang, Feng Yu, Jing Ouyang, Panpan Liu, Yingying Dai, Howard McLeod

J Immunother Cancer· June 2025

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Causal effects of immune cells on the efficacy and adverse drug reactions of platinum drugs.
Wanting Li, Bing Yu, Qi Xiao, Zhao Zhang, Hanxue Huang, Howard L McLeod

Acta Biochim Biophys Sin (Shanghai)· May 2025

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Pharmacogenomics in Oncology-Running Out of Excuses for Slow Adoption.
Howard L McLeod, D Grace Nguyen

JAMA Netw Open· December 2024

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Multicenter validation of an RNA-based assay to predict anti-PD-1 disease control in patients with recurrent or metastatic head and neck squamous cell carcinoma: the PREDAPT study.
Kevin C Flanagan, Jon Earls, Jeffrey Hiken, Rachel L Wellinghoff, Michelle M Ponder, Howard L McLeod

J Immunother Cancer· November 2024

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Recommendations for pharmacogenetic testing in clinical practice guidelines in the US.
Daniel L Hertz, Chad A Bousman, Howard L McLeod, Andrew A Monte, Deepak Voora

Am J Health Syst Pharm· August 2024

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Deceptive learning in histopathology.
Sahar Shahamatdar, Daryoush Saeed-Vafa, Drew Linsley, Farah Khalil, Katherine Lovinger, Howard T McLeod

Histopathology· July 2024

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TRPV1 inhibition suppresses non-small cell lung cancer progression by inhibiting tumour growth and enhancing the immune response.
Yang Wang, Yu Zhang, Jing Ouyang, Hanying Yi, Shiyu Wang, Howard L Mcleod

Cell Oncol (Dordr)· June 2024

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Common variation in a long non-coding RNA gene modulates variation of circulating TGF-β2 levels in metastatic colorectal cancer patients (Alliance).
Julia C F Quintanilha, Alexander B Sibley, Yingmiao Liu, Donna Niedzwiecki, Susan Halabi, Howard L McLeod

BMC Genomics· May 2024

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Overcoming Barriers to Discovery and Implementation of Equitable Pharmacogenomic Testing in Oncology.
Sharon P Shriver, Devon Adams, Brittany Avin McKelvey, Jeannine S McCune, Dale Miles, Howard L McLeod

J Clin Oncol· April 2024

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Dihydropyrimidine dehydrogenase gene variants for predicting grade 4-5 fluoropyrimidine-induced toxicity: FUSAFE individual patient data meta-analysis.
Gwénaël Le Teuff, Nathalie Cozic, Jean-Christophe Boyer, Valérie Boige, Robert B Diasio, Howard L McLeod

Br J Cancer· March 2024

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Pharmacogenetic and clinical risk factors for bevacizumab-related gastrointestinal hemorrhage in prostate cancer patients treated on CALGB 90401 (Alliance).
Jai N Patel, Chen Jiang, Kouros Owzar, Daniel L Hertz, Janey Wang, Howard L McLeod

Pharmacogenomics J· March 2024

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HerediGene Population Study IT infrastructure: A model to support genomic research recruitment and precision public health.
David P Taylor, Bret S E Heale, Benjamin Chisum, G Bryce Christensen, Darin F Wilcox, Howard L McLeod

AMIA Annu Symp Proc· January 2024

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CYP2D6-guided opioid therapy for adults with cancer pain: A randomized implementation clinical trial.
Scott A Mosley, Emily Cicali, Alex Del Cueto, Diane G Portman, Kristine A Donovan, Howard L McLeod

Pharmacotherapy· December 2023

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Common variation in a long non-coding RNA gene modulates variation of circulating TGF-2 levels in metastatic colorectal cancer patients (Alliance).
Julia C F Quintanilha, Alexander B Sibley, Yingmiao Liu, Donna Niedzwiecki, Susan Halabi, Howard L McLeod

medRxiv· December 2023

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Multidimensional biomarker predicts disease control in response to immunotherapy in recurrent or metastatic head and neck squamous-cell carcinoma.
Kevin C Flanagan, Jon Earls, Ian Schillebeeckx, Jeffrey Hiken, Rachel L Wellinghoff, Howard Mcleod

J Cancer Res Clin Oncol· November 2023

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Pharmacogenomic Analyses Implicate B Cell Developmental Status and as Determinants of Sensitivity toward Anti-CD20 Monoclonal Antibody Therapy.
George W Small, Farida S Akhtari, Adrian J Green, Tammy M Havener, Michael Sikes, Howard L McLeod

Cells· June 2023

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Testing: Time to Put Patient Safety First.
Sharyn D Baker, Susan E Bates, Gabriel A Brooks, William L Dahut, Robert B Diasio, Howard L McLeod

J Clin Oncol· May 2023

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Biomarkers for Response to Anti-PD-1/Anti-PD-L1 Immune Checkpoint Inhibitors: A Large Meta-Analysis.
Arshiya Mariam, Suneel Kamath, Kimberly Schveder, Howard L McLeod, Daniel M Rotroff

Oncology (Williston Park)· May 2023

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Gene Expression Associated with Drug Response Variation of Temozolomide and Clinical Outcomes in Glioma Patients.
Ricardo D Gonzalez, George W Small, Adrian J Green, Farida S Akhtari, Tammy M Havener, Howard L McLeod

Pharmaceuticals (Basel)· May 2023

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Gene Expression Associated with Variation in Drug Response to Oxaliplatin and Clinical Outcomes in Colorectal Cancer Patients.
Ricardo D Gonzalez, George W Small, Adrian J Green, Farida S Akhtari, Alison A Motsinger-Reif, Howard L McLeod

Pharmaceuticals (Basel)· May 2023

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The Development of an Infrastructure to Facilitate the Use of Whole Genome Sequencing for Population Health.
Nephi A Walton, Brent Hafen, Sara Graceffo, Nykole Sutherland, Melanie Emmerson, Howard L McLeod

J Pers Med· November 2022

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